ChemicalBook--->CAS DataBase List--->109-07-9

109-07-9

109-07-9 Structure

109-07-9 Structure
IdentificationMore
[Name]

2-Methylpiperazine
[CAS]

109-07-9
[Synonyms]

2-METHYLDIETHYLENEDIAMINE
(+/-)-2-METHYLPIPERAZINE
2-METHYLPIPERAZINE
2MPRZ
MP
2-methyl-piperazin
2-METHYLPIPERAZINE/LOMEFLOXCIN
2-Methylpiperazine ,99%
[EINECS(EC#)]

203-644-2
[Molecular Formula]

C5H12N2
[MDL Number]

MFCD00005954
[Molecular Weight]

100.16
[MOL File]

109-07-9.mol
Chemical PropertiesBack Directory
[Appearance]

white to yellow crystalline powder and chunks
[Melting point ]

61-63 °C (lit.)
[Boiling point ]

155 °C/763 mmHg (lit.)
[density ]

0.817 g/cm
[refractive index ]

1.4378 (estimate)
[Fp ]

149 °F
[storage temp. ]

Flammables area
[solubility ]

435g/l
[form ]

Crystalline Powder, Crystals and/or Chunks
[pka]

pK1:5.62(+2);pK2:9.60(+1) (25°C)
[color ]

White to yellow
[PH]

11-12 (50g/l, H2O)
[Water Solubility ]

78 g/100 mL (25 ºC)
[Sensitive ]

Air Sensitive & Hygroscopic
[Detection Methods]

GC,NMR
[BRN ]

383566
[Henry's Law Constant]

5.0×103 mol/(m3Pa) at 25℃, Nguyen (2013)
[InChI]

1S/C5H12N2/c1-5-4-6-2-3-7-5/h5-7H,2-4H2,1H3
[InChIKey]

JOMNTHCQHJPVAZ-UHFFFAOYSA-N
[SMILES]

CC1CNCCN1
[CAS DataBase Reference]

109-07-9(CAS DataBase Reference)
[NIST Chemistry Reference]

Piperazine, 2-methyl-(109-07-9)
[EPA Substance Registry System]

109-07-9(EPA Substance)
Safety DataBack Directory
[Symbol(GHS) ]

Flame (GHS02)Corrosion (GHS05)
GHS02,GHS05
[Signal word ]

Danger
[Hazard statements ]

H228-H314
[Precautionary statements ]

P210-P240-P260-P280-P303+P361+P353-P305+P351+P338
[Hazard Codes ]

F,Xi
[Risk Statements ]

R11:Highly Flammable.
R36/37/38:Irritating to eyes, respiratory system and skin .
[Safety Statements ]

S16:Keep away from sources of ignition-No smoking .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S36:Wear suitable protective clothing .
[RIDADR ]

UN 1325 4.1/PG 2
[WGK Germany ]

2
[RTECS ]

TM1225020
[F ]

10
[TSCA ]

Yes
[REACH Registrations]

Active
[HazardClass ]

4.1
[PackingGroup ]

III
[HS Code ]

29335900
[Storage Class]

4.1B - Flammable solid hazardous materials
[Hazard Classifications]

Eye Dam. 1
Flam. Sol. 1
Skin Corr. 1B
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Ethylenediamine-->Propylene oxide-->3-Methyl-1-benzyl-piperazine-->2,5-Dimethylpiperazine-->2,6-Dimethylpiperazine-->D(+)-Glucose
[Preparation Products]

Lomefloxacin-->4-N-Boc-2-Methyl-piperazine-->Lomefloxacin hydrochloride-->TEMAFLOXACIN-->2-Methylpyrazine-->1-cyclopropyl-6-fluoro-5-methyl-7-(3-methylpiperazin-1-yl)-4-oxo-quino line-3-carboxylic acid-->(R)-(-)-2-Methylpiperazine-->DL-Alaninol-->1,2-Dimethyl-piperazine-->Piperazine
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

2-Methylpiperazine(109-07-9).msds
Hazard InformationBack Directory
[Chemical Properties]

white to yellow crystalline powder and chunks
[Uses]

2-Methylpiperazine is used as a reagent in the design, synthesis and biological evaluation of diaminoquinazolines as b-catenine/Tcell transcription factor 4 (Tcf4) pathway inhibitor.
[Purification Methods]

Purify it by zone melting and by distillation. It is hygroscopic. The picrate has m 275-276o. [Beilstein 23 II 16, 23 III/IV 393, 23/3 V 267.]
Spectrum DetailBack Directory
[Spectrum Detail]

2-Methylpiperazine(109-07-9)MS
2-Methylpiperazine(109-07-9)1HNMR
2-Methylpiperazine(109-07-9)13CNMR
2-Methylpiperazine(109-07-9)IR1
2-Methylpiperazine(109-07-9)Raman
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

2-Methylpiperazine, 98%(109-07-9)
[Alfa Aesar]

(+/-)-2-Methylpiperazine, 98%(109-07-9)
[Sigma Aldrich]

109-07-9(sigmaaldrich)
[TCI AMERICA]

2-Methylpiperazine,>99.0%(GC)(109-07-9)
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