| Identification | More | [Name]
1,5-Pentanedioic acid | [CAS]
110-94-1 | [Synonyms]
1,3-PROPANEDICARBOXYLIC ACID
1,5-PENTADIOIC ACID
1,5-PENTANEDIOIC ACID
DICARBOXYLIC ACID C5
GLUTARIC ACID
GLUTARIC ACID AND ANHYDRIDE
N-PYROTARTARIC ACID
Pentandioic acid
PENTANEDIOIC ACID
PROPANE-1,3-DICARBOXYLIC ACID
RARECHEM AL BO 0175
a,-Propanedicarboxylicacid
glutaric
Glutarsaure
Glutaric acid,(Pentanedioic acid
propane-1,3-dica
Glutaric Acid, Reagent
Propane-1,5-dicarboxylic acid
Pentanedioic acid,Glutaric acid
Glutarsure | [EINECS(EC#)]
203-817-2 | [Molecular Formula]
C5H8O4 | [MDL Number]
MFCD00004410 | [Molecular Weight]
132.11 | [MOL File]
110-94-1.mol |
| Chemical Properties | Back Directory | [Appearance]
white or off-white crystals | [Melting point ]
95-98 °C (lit.) | [Boiling point ]
200 °C/20 mmHg (lit.) | [density ]
1,429 g/cm3 | [vapor pressure ]
0.022 hPa (18.5 °C) | [refractive index ]
nD106 1.41878 | [Fp ]
200°C/20mm | [storage temp. ]
2-8°C | [solubility ]
water: soluble5mg/mL, clear to slightly hazy, colorless to faintly yellow | [form ]
Crystalline Powder | [pka]
4.31(at 25℃) | [color ]
Orange | [PH]
3.7(1 mM solution);3.17(10 mM solution);2.66(100 mM solution) | [Stability:]
Stable. Incompatible with bases, oxidizing agents, reducing agents. | [Water Solubility ]
430 g/L (20 ºC) | [Merck ]
14,4473 | [BRN ]
1209725 | [InChIKey]
JFCQEDHGNNZCLN-UHFFFAOYSA-N | [LogP]
-0.26 at 25℃ | [CAS DataBase Reference]
110-94-1(CAS DataBase Reference) | [NIST Chemistry Reference]
Pentanedioic acid(110-94-1) | [EPA Substance Registry System]
110-94-1(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36:Irritating to the eyes.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37/39:Wear suitable gloves and eye/face protection .
S36:Wear suitable protective clothing . | [WGK Germany ]
1
| [RTECS ]
MA3740000
| [TSCA ]
Yes | [HS Code ]
29171990 | [Hazardous Substances Data]
110-94-1(Hazardous Substances Data) |
| Hazard Information | Back Directory | [General Description]
Colorless crystals or white solid. | [Reactivity Profile]
GLUTARIC ACID(110-94-1) is a carboxylic acid. Carboxylic acids donate hydrogen ions if a base is present to accept them. They react in this way with all bases, both organic (for example, the amines) and inorganic. Their reactions with bases, called "neutralizations", are accompanied by the evolution of substantial amounts of heat. Neutralization between an acid and a base produces water plus a salt. Carboxylic acids with six or fewer carbon atoms are freely or moderately soluble in water; those with more than six carbons are slightly soluble in water. Soluble carboxylic acid dissociate to an extent in water to yield hydrogen ions. The pH of solutions of carboxylic acids is therefore less than 7.0. Many insoluble carboxylic acids react rapidly with aqueous solutions containing a chemical base and dissolve as the neutralization generates a soluble salt. Carboxylic acids in aqueous solution and liquid or molten carboxylic acids can react with active metals to form gaseous hydrogen and a metal salt. Such reactions occur in principle for solid carboxylic acids as well, but are slow if the solid acid remains dry. Even "insoluble" carboxylic acids may absorb enough water from the air and dissolve sufficiently in GLUTARIC ACID(110-94-1) to corrode or dissolve iron, steel, and aluminum parts and containers. Carboxylic acids, like other acids, react with cyanide salts to generate gaseous hydrogen cyanide. The reaction is slower for dry, solid carboxylic acids. Insoluble carboxylic acids react with solutions of cyanides to cause the release of gaseous hydrogen cyanide. Flammable and/or toxic gases and heat are generated by the reaction of carboxylic acids with diazo compounds, dithiocarbamates, isocyanates, mercaptans, nitrides, and sulfides. Carboxylic acids, especially in aqueous solution, also react with sulfites, nitrites, thiosulfates (to give H2S and SO3), dithionites (SO2), to generate flammable and/or toxic gases and heat. Their reaction with carbonates and bicarbonates generates a harmless gas (carbon dioxide) but still heat. Like other organic compounds, carboxylic acids can be oxidized by strong oxidizing agents and reduced by strong reducing agents. These reactions generate heat. A wide variety of products is possible. Like other acids, carboxylic acids may initiate polymerization reactions; like other acids, they often catalyze (increase the rate of) chemical reactions This compound reacts with bases, oxidizing agents and reducing agents. | [Air & Water Reactions]
Water soluble. | [Fire Hazard]
Flash point data for this chemical are not available; however, GLUTARIC ACID is probably combustible. | [Description]
Glutaric acid is a dicarboxylic acid with carboxylic acid functional groups at either either end of the molecular chain. The terminal carboxylic acid groups can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. | [Chemical Properties]
white or off-white crystals | [Occurrence]
Glutaric acid occurs in washings from fleece and, together with malonic acid, in the juice of unripened sugar beet. | [Uses]
Glutaric acid is used as the raw material for organic synthesis, pharmaceutical intermediate and synthetic resin. It serves as a precursor in the production of polyester polyols, polyamides, ester plasticizers and corrosion inhibitors. It is useful to decrease polymer elasticity and in the synthesis surfactants and metal finishing compounds. It acts as an intermediate during the catabolism of lysine in mammals. | [Application]
The applications of glutaric acid, e.g., as an intermediate, are limited. Its use as a starting material in the manufacture of maleic acid has no commercial importance. it does not usually reach the market because it is converted into dibasic esters and sold as environmentally friendly solvents. | [Definition]
ChEBI: An alpha,omega-dicarboxylic acid that is a linear five-carbon dicarboxylic acid. | [Preparation]
glutaric acid is produced as a by-product of the production process of adipic acid (about 2% of the output of an adipic acid plant is glutaric); Glutaric acid can be produced through various chemical routes, for example, from cyclopentane by oxidation with molecular oxygen and cobalt (III) catalysts or by ozonolysis; and from cyclopentanol–cyclopentanone by oxidation with oxygen and Co(CH3CO2)2, with potassium peroxide in benzene, or with N2O4 or nitric acid. Together with succinic acid, glutaric acid is formed as a by-product during oxidation of cyclohexanol–cyclohexanone in the adipic acid production process. | [Synthesis Reference(s)]
Journal of the American Chemical Society, 78, p. 2489, 1956 DOI: 10.1021/ja01592a042
Organic Syntheses, Coll. Vol. 1, p. 290, 1941
Synthetic Communications, 10, p. 205, 1980 DOI: 10.1080/00397918008064223 | [Flammability and Explosibility]
Notclassified | [Purification Methods]
Crystallise the acid from *benzene, CHCl3, distilled water or *benzene containing 10% (w/w) of diethyl ether. Dry it under vacuum. [Beilstein 2 IV 1934.] |
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