| Identification | More | [Name]
3-Hydroxy-2-methylpyridine | [CAS]
1121-25-1 | [Synonyms]
2-METHYL-3-PYRIDINOL
3-HYDROXY-2-METHYLPYRIDINE
3-HYDROXY-2-PICOLINE
2-Methyl-3-hydroxypyridine
3-Pyridinol, 2-methyl-
3-HYDROXY-2-METHYLPYRIDINE 99%
3-HYDROXY-2-METHYLPYRIDINE 2-METHYLPYRIDIN-3-OL
3-HYDROXY-2-METHYLPYRIDINE (3-HYDROXY-2-PICOLINE)
2-METHYL-3-PHENYLTHIOPHENE
6-Methylpyridin-5-ol | [EINECS(EC#)]
214-327-3 | [Molecular Formula]
C6H7NO | [MDL Number]
MFCD00082538 | [Molecular Weight]
109.13 | [MOL File]
1121-25-1.mol |
| Chemical Properties | Back Directory | [Appearance]
beige-brown powder | [Melting point ]
168-169 °C (lit.) | [Boiling point ]
204.59°C (rough estimate) | [density ]
1.1143 (rough estimate) | [refractive index ]
1.5040 (estimate) | [storage temp. ]
Inert atmosphere,Room Temperature | [solubility ]
DMSO, Methanol | [form ]
Powder | [pka]
10.38±0.10(Predicted) | [color ]
Beige-brown | [BRN ]
107937 | [InChI]
InChI=1S/C6H7NO/c1-5-6(8)3-2-4-7-5/h2-4,8H,1H3 | [InChIKey]
AQSRRZGQRFFFGS-UHFFFAOYSA-N | [SMILES]
C1(C)=NC=CC=C1O | [LogP]
0.314 (est) | [CAS DataBase Reference]
1121-25-1(CAS DataBase Reference) | [NIST Chemistry Reference]
3-Pyridinol, 2-methyl-(1121-25-1) |
| Questions And Answer | Back Directory | [Synthesis]
0.03 mol 2-acetylfuran, 35 mL methanol, a certain amount of ammonium salt, and 20.4 g 25% ammonia water were added to a 100 mL custom-made high-temperature digestion vessel. The mixture was magnetically stirred and reacted at an oil bath temperature of 170℃ for 16 h. After the reaction was complete, the mixture was filtered, and the filtrate was decolorized three times with activated carbon. The solvent was removed by rotary evaporation to obtain a gray solid, which was purified by recrystallization from 50% ethanol and water. 2-Methyl-3-hydroxypyridine, melting point 167–171℃, molar yield 33.2%. |
| Safety Data | Back Directory | [Symbol(GHS) ]
 
GHS05,GHS07 | [Signal word ]
Danger | [Hazard statements ]
H302-H315-H318-H335 | [Precautionary statements ]
P280-P301+P312+P330-P302+P352-P305+P351+P338+P310 | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R22:Harmful if swallowed.
R37/38:Irritating to respiratory system and skin .
R41:Risk of serious damage to eyes.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37/39:Wear suitable gloves and eye/face protection .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [HS Code ]
29333990 |
| Hazard Information | Back Directory | [Chemical Properties]
beige-brown powder | [Uses]
3-Hydroxy-2-methylpyridine is used in the preparation of substituted pyridine and pyrimidine derivatives and their use in treating viral infections.
| [Synthesis Reference(s)]
Journal of the American Chemical Society, 71, p. 2969, 1949 DOI: 10.1021/ja01177a007 | [General Description]
Vitamin B6 is an active 3-hydroxy-2-methylpyridine derivative. |
|
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J & K SCIENTIFIC LTD.
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18210857532 18210857532 |
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Alfa Aesar
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400-6106006 |
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Energy Chemical
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Jia Xing Isenchem Co.,Ltd
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