| Identification | More | [Name]
3-Hydroxy-6-methylpyridine | [CAS]
1121-78-4 | [Synonyms]
2-METHYL-5-HYDROXY PYRIDINE
3-HYDROXY-6-METHYLPYRIDINE
5-HYDROXY-2-METHYLPYRIDINE
5-HYDROXY-2-PICOLINE
6-METHYL-3-HYDROXYPYRIDINE
6-METHYL-3-PYRIDINOL
6-METHYLPYRIDIN-3-OL
TIMTEC-BB SBB004349
6-methyl-3-pyridino
3-HYDROXY-6-METHYLPYRIDINE 99%
5-HYDROXY-2-METHYLPYRIDINE 99%
3-HYDOXY-6-METHYLPYRIDINE
5-HYDROXY-2-METHYLPYRIDINE (5-HYDROXY-2-PICOLINE)
2-Methylpyridin-5-ol
6-Methyl-3-pyridineol | [EINECS(EC#)]
214-337-8 | [Molecular Formula]
C6H7NO | [MDL Number]
MFCD00006339 | [Molecular Weight]
109.13 | [MOL File]
1121-78-4.mol |
| Chemical Properties | Back Directory | [Appearance]
beige to light tan crystalline powder | [Melting point ]
168-170 °C(lit.)
| [Boiling point ]
204.59°C (rough estimate) | [density ]
1.1143 (rough estimate) | [refractive index ]
1.5040 (estimate) | [storage temp. ]
Inert atmosphere,2-8°C | [solubility ]
dichloromethane: soluble | [form ]
Crystalline Powder | [pka]
9.49±0.10(Predicted) | [color ]
Beige to light tan | [BRN ]
107077 | [InChI]
InChI=1S/C6H7NO/c1-5-2-3-6(8)4-7-5/h2-4,8H,1H3 | [InChIKey]
DHLUJPLHLZJUBW-UHFFFAOYSA-N | [SMILES]
C1=NC(C)=CC=C1O | [LogP]
0.418 (est) | [CAS DataBase Reference]
1121-78-4(CAS DataBase Reference) | [NIST Chemistry Reference]
3-Pyridinol, 6-methyl-(1121-78-4) |
| Questions And Answer | Back Directory | [Synthesis]
solution of K₂CO₃ (0.552 g, 4 mmol) in 30 mL of methanol was added to a polysubstituted 5-(trimethylsilyl)pent-1-en-4-yn-3-ol. The mixture was stirred at room temperature. The reaction mixture was filtered through a short silica gel stopper. The mixture was concentrated and filtered. The product, 3-hydroxy-6-methylpyridine, was purified by rapid chromatography. |
| Safety Data | Back Directory | [Symbol(GHS) ]
 
GHS05,GHS07 | [Signal word ]
Danger | [Hazard statements ]
H302-H315-H318-H335 | [Precautionary statements ]
P280-P301+P312+P330-P302+P352-P305+P351+P338+P310 | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R22:Harmful if swallowed.
R37/38:Irritating to respiratory system and skin .
R41:Risk of serious damage to eyes.
R40:Limited evidence of a carcinogenic effect.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S39:Wear eye/face protection .
S24/25:Avoid contact with skin and eyes .
S36:Wear suitable protective clothing .
S22:Do not breathe dust . | [WGK Germany ]
3
| [RTECS ]
UU7714900
| [HS Code ]
29333990 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral
Eye Dam. 1
Skin Irrit. 2
STOT SE 3 | [Toxicity]
mouse,LD50,intraperitoneal,846mg/kg (846mg/kg),Toxicon. Vol. 23, Pg. 815, 1985. |
| Hazard Information | Back Directory | [Chemical Properties]
beige to light tan crystalline powder | [Uses]
- 5-Hydroxy-2-methylpyridine was used as starting reagent for the synthesis of 5-[(4-methoxybenzyl)oxy]-2-pyridinecarbaldehyde.
- It was used in synthesis of [HNC6H6OH]2[Cu(NC5H5)4(NbOF5)2].
- It was used as ligand of a platinum complex which showed protein kinase inhibitory action at nanomolar levels.
- It forms a chiral pyridinium ionic liquid on reaction with L-menthol chloromethyl ether.
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| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
|