| Identification | More | [Name]
2-Amino-5-nitrothiazole | [CAS]
121-66-4 | [Synonyms]
2-AMINO-5-NITRO-1,3-THIAZOLE
2-AMINO-5-NITROTHIAZOLE
2-AMINO-5-NITRO-THIAZOLE HYDROCHLORIDE
5-NITRO-1,3-THIAZOL-2-AMINE
5-nitro-2-aminothiazole
AKOS 203
AKOS BBS-00006479
AURORA KA-644
ENHEPTIN
ENHEPTYNE
ENTRAMINE
LABOTEST-BB LT00129612
2-amino-5-nitro-thiazol
5-nitro-2-thiazolamin
5-nitro-2-Thiazolamine
5-nitro-2-thiazolylamine
aminonitrothiazole
aminonitrothiazolum
aminzolsoluble
amnizolsoluble | [EINECS(EC#)]
204-490-9 | [Molecular Formula]
C3H3N3O2S | [MDL Number]
MFCD00005326 | [Molecular Weight]
145.14 | [MOL File]
121-66-4.mol |
| Chemical Properties | Back Directory | [Appearance]
greenish yellow, to orange or brown powder | [Melting point ]
195-200 °C (dec.) (lit.) | [Boiling point ]
345.1±15.0 °C(Predicted) | [density ]
1.583 (estimate) | [refractive index ]
1.6740 (estimate) | [storage temp. ]
Keep in dark place,Inert atmosphere,2-8°C | [solubility ]
95% ethanol: soluble1g/150g at 20°C | [form ]
Powder | [pka]
1.26±0.10(Predicted) | [color ]
Yellow | [Stability:]
Stable. Incompatible with strong acids, strong oxidizing agents, acid chlorides, acid anhydrides. | [Water Solubility ]
<0.1 g/100 mL at 20 ºC | [Sensitive ]
Light Sensitive | [Merck ]
14,457 | [BRN ]
126797 | [Henry's Law Constant]
1.9×106 mol/(m3Pa) at 25℃, HSDB (2015) | [InChI]
1S/C3H3N3O2S/c4-3-5-1-2(9-3)6(7)8/h1H,(H2,4,5) | [InChIKey]
MIHADVKEHAFNPG-UHFFFAOYSA-N | [SMILES]
Nc1ncc(s1)[N+]([O-])=O | [CAS DataBase Reference]
121-66-4(CAS DataBase Reference) | [IARC]
3 (Vol. 31, Sup 7) 1987 | [EPA Substance Registry System]
121-66-4(EPA Substance) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H302-H315-H319-H335 | [Precautionary statements ]
P261-P264-P270-P301+P312-P302+P352-P305+P351+P338 | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin .
R40:Limited evidence of a carcinogenic effect.
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S24/25:Avoid contact with skin and eyes .
S36/37:Wear suitable protective clothing and gloves . | [WGK Germany ]
3
| [RTECS ]
XJ2800000
| [F ]
8 | [Hazard Note ]
Irritant | [TSCA ]
Yes | [REACH Registrations]
Active | [HS Code ]
29341000 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 | [Safety Profile]
Poison by intraperitoneal route. Experimental reproductive effects. Questionable carcinogen with experimental carcinogenic, tumorigenic, and neoplastigenic data. Mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and SO,. Incompatible with HNO3 and H2SO4. An antiprotozoal agent. | [Hazardous Substances Data]
121-66-4(Hazardous Substances Data) |
| Hazard Information | Back Directory | [General Description]
Greenish-yellow to orange-yellow fluffy powder or a brown chunky powder. Slightly bitter taste. Used as a veterinary medicine. | [Reactivity Profile]
2-AMINO-5-NITROTHIAZOLE(121-66-4) may be sensitive to light. Incompatible with nitric acid and sulfuric acid. Also incompatible with strong oxidizing agents, strong acids, acid chlorides and acid anhydrides. A preparative hazard . | [Air & Water Reactions]
Insoluble in water. | [Fire Hazard]
Flash point data for this chemical are not available. 2-AMINO-5-NITROTHIAZOLE is probably combustible. | [Chemical Properties]
greenish yellow, to orange or brown powder | [Definition]
ChEBI: 2-Amino-5-nitrothiazole is a member of thiazoles and a C-nitro compound. | [Production Methods]
Early production of 2-Amino-5-nitrothiazole was
based on nitration of 2-acetylaminothiazole
and careful hydrolysis. Direct nitration of
2-aminothiazole gives a cleaner product and is
best achieved by adding 2-aminothiazole nitrate [57530-25-3] to concentrated sulfuric acid
at 0 – 10 ℃. This process and the nitration of o-anisidine are the only large-scale
processes based on rearrangement of an amine
nitrate, and both are potentially hazardous due
to the possibility of runaway exothermic reactions. | [Potential Exposure]
2-Amino-5-nitrothiazole is a synthetic veterinary antiprotozoal agent used since 1950 to treat farm fowl and pigeons. It is also used as an intermediate in manufacturing a group of dyes known as disperse azo dyes. It is not known to occur as a natural product. People may be exposed to 2-amino-5-nitrothiazole through contact with birds treated with the drug, releases from poultry farms, and occupational exposures in the dye industry.
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| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
Jia Xing Isenchem Co.,Ltd
|
| Telephone: |
0573-85285100 18627885956 |
| Website: |
https://www.chemicalbook.com/ShowSupplierProductsList14265/0_EN.htm |
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