ChemicalBook--->CAS DataBase List--->7305-71-7

7305-71-7

7305-71-7 Structure

7305-71-7 Structure
IdentificationMore
[Name]

2-Amino-5-methylthiazole
[CAS]

7305-71-7
[Synonyms]

2-AMINO-5-METHYLTHIAZOLE
5-METHYL-1,3-THIAZOL-2-AMINE
5-METHYL-2-THIAZOLAMINE
5-METHYL-THIAZOL-2-YLAMINE
AKOS BBS-00006638
BUTTPARK 18\10-87
LABOTEST-BB LT00080645
2-Thiazolamine, 5-methyl-
2-AMINO-5-METHYLTHIAZOLE, WACKER QUALITY
2,5-amth
2-Amino-5-methylthiazole, 98+%
2-Amino-5-methylthiazole ,99%
[EINECS(EC#)]

423-800-5
[Molecular Formula]

C4H6N2S
[MDL Number]

MFCD00078317
[Molecular Weight]

114.17
[MOL File]

7305-71-7.mol
Chemical PropertiesBack Directory
[Appearance]

white to light yellow crystal powde
[Melting point ]

93-98 °C (lit.)
[Boiling point ]

232.5±9.0 °C(Predicted)
[density ]

1.258±0.06 g/cm3(Predicted)
[vapor pressure ]

0.153-1.24Pa at 20-40℃
[storage temp. ]

2-8°C
[solubility ]

soluble in Methanol
[form ]

Powder
[pka]

5.42±0.10(Predicted)
[color ]

Brown
[Detection Methods]

GC,NMR
[BRN ]

109603
[InChI]

1S/C4H6N2S/c1-3-2-6-4(5)7-3/h2H,1H3,(H2,5,6)
[InChIKey]

GUABFMPMKJGSBQ-UHFFFAOYSA-N
[SMILES]

Cc1cnc(N)s1
[LogP]

1.61 at 38℃
[Surface tension]

72.6mN/m at 1.02g/L and 20℃
[CAS DataBase Reference]

7305-71-7(CAS DataBase Reference)
[NIST Chemistry Reference]

Thiazole, 2-amino-5-methyl-(7305-71-7)
Questions And AnswerBack Directory
[Preparation]

Using 1,2,3-trichloropropane as a starting material, it reacts with sodium hydroxide to produce 2,3-dichloro-1-propene, which then reacts with potassium thiocyanate and isomerizes to produce 2-chloro-2-propenyl isothiocyanate. This is then reacted with ammonia to give N-(2-chloro-2-propenyl)thiourea, which is subsequently cyclized in the presence of 80% sulfuric acid to give 2-amino-5-methylthiazole.

Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)Health Hazard (GHS08)Environment (GHS09)
GHS07,GHS08,GHS09
[Signal word ]

Warning
[Hazard statements ]

H302-H373-H410
[Precautionary statements ]

P260-P264-P270-P273-P301+P312-P314
[Hazard Codes ]

Xn,N,Xi
[Risk Statements ]

R22:Harmful if swallowed.
R48/22:Harmful: danger of serious damage to health by prolonged exposure if swallowed .
R50/53:Very Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment .
R36/37/38:Irritating to eyes, respiratory system and skin .
[Safety Statements ]

S60:This material and/or its container must be disposed of as hazardous waste .
S61:Avoid release to the environment. Refer to special instructions safety data sheet .
S29:Do not empty into drains .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37/39:Wear suitable gloves and eye/face protection .
[RIDADR ]

2811
[WGK Germany ]

3
[Hazard Note ]

Irritant/Keep Cold
[REACH Registrations]

Active
[HazardClass ]

9
[PackingGroup ]

III
[HS Code ]

29349990
[Storage Class]

11 - Combustible Solids
[Hazard Classifications]

Acute Tox. 4 Oral
Aquatic Acute 1
Aquatic Chronic 1
STOT RE 2
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Thiourea-->1,2-Propadiene, 1-isothiocyanato--->Meloxicam-->2-Bromopriopionaldehyde diethyl acetal-->2-Bromo-propionaldehyde-->Chloropropanal-->2-Methyl-4-hydroxy-2H-1,2-benzisothiazine-3-carboxylic acid ethyl ester-1,1-diox-->Chloroacetone-->Propionaldehyde-->Potassium thiocyanate-->Salicylaldehyde
[Preparation Products]

2-Chloro-5-methylthiazole-->5-Methylthiazole-->Thiazole, 2-fluoro-5-Methyl--->5-methyl-4-(trifluoromethyl)thiazol-2-amine-->Ethyl 2-Methyl-5-oxo-[1,3]thiazolo[3,2-a]pyridine-6-carboxylate-->Formamide, N-(5-methyl-2-thiazolyl)-
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

2-Amino-5-methylthiazole(7305-71-7).msds
Hazard InformationBack Directory
[Chemical Properties]

white to light yellow crystal powde
[Uses]

An aminothiazole derivative used in characterization and DNA-interaction studies via formation of metal complexes that bind competitively to DNA. 2-Amino-5-methylthiazole can be used in solar cells to influence the interaction with the TiO2 photoelectrode, which in turn alters the dye-sensitized solar cell performance.
[General Description]

2-Amino-5-methylthiazole is a heterocyclic building block. It is one of the major alkaline metabolite of tenoxicam (TX) and meloxicam (MX).
Spectrum DetailBack Directory
[Spectrum Detail]

2-Amino-5-methylthiazole(7305-71-7)MS
2-Amino-5-methylthiazole(7305-71-7)1HNMR
2-Amino-5-methylthiazole(7305-71-7)13CNMR
2-Amino-5-methylthiazole(7305-71-7)IR1
2-Amino-5-methylthiazole(7305-71-7)IR2
2-Amino-5-methylthiazole(7305-71-7)Raman
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

2-Amino-5-methylthiazole, 98%(7305-71-7)
[Alfa Aesar]

2-Amino-5-methylthiazole, 98+%(7305-71-7)
[Sigma Aldrich]

7305-71-7(sigmaaldrich)
[TCI AMERICA]

2-Amino-5-methylthiazole,>97.0%(T)(7305-71-7)
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