| Identification | More | [Name]
Cefepime hydrochloride | [CAS]
123171-59-5 | [Synonyms]
Cefepim dihydrochloride
Pyrrolidinium, 1-[[(6R,7R)-7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-1-methyl-, chloride, monohydrochloride, monohydrate
Pyrrolidinium, 1-[[7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-1-methyl-, chloride, monohydrochloride, monohydrate, [6R-[6α,7β(Z)]]-
(6R,7R)-7-[(Z)-2-(2-Amino-4-thiazolyl)-2-(methoxyimino)acetamido]-3-[1-(1-methylpyrrolidinyl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-2-carboxylic acid hydrochloride monohydrate
Cefepime hydrochloride
CEFEPIME HYDROCHLORIDE (BUFFERED WITH ARGININE)
1-[[(6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-1-methyl-pyrrolidinium Inner Salt Hydrochloride Monohydrate
Axepim
Cefepime Hydrochloride Monohydrate
Cepimex
Maxipime
Cefepime 2HCl | [EINECS(EC#)]
642-959-3 | [Molecular Formula]
C19H25ClN6O5S2 | [MDL Number]
MFCD06804606 | [Molecular Weight]
517.02 | [MOL File]
123171-59-5.mol |
| Chemical Properties | Back Directory | [Appearance]
White to pale yellow powder | [Melting point ]
150°C (dec.) | [storage temp. ]
Store at 0-5°C | [solubility ]
Soluble in DMSO | [form ]
powder | [color ]
white to faint yellow | [Sensitive ]
Light Sensitive | [Usage]
Semisynthetic, fourth generation cephalosporin antibiotic. Antibacterial | [Major Application]
pharmaceutical (small molecule) | [InChIKey]
LRAJHPGSGBRUJN-ZVMPLFRQNA-N | [SMILES]
C(C1=C(CS[C@]2([H])[C@H](NC(=O)/C(/C3N=C(N)SC=3)=N\OC)C(=O)N12)C[N+]1(CCCC1)C)(=O)O.[Cl-].Cl.O |&1:5,7,r| | [CAS DataBase Reference]
123171-59-5(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R42/43:May cause sensitization by inhalation and skin contact . | [Safety Statements ]
S22:Do not breathe dust .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [WGK Germany ]
3 | [HS Code ]
2941906000 | [Storage Class]
11 - Combustible Solids |
| Hazard Information | Back Directory | [Chemical Properties]
White to pale yellow powder | [Uses]
antipsoriatic, protein synthesis inhibitor | [Uses]
Cefepime hydrochloride monohydrate is used as a broad spectrum antibiotic targeting a wide variety of naturally antibiotic resistant Gram-positive and Gram-negative bacteria. It is resistant to hydrolysis by common plasmid and/or chromosomally-mediated β-lactamases. | [Uses]
Semisynthetic, fourth generation cephalosporin antibiotic. Antibacterial | [Definition]
ChEBI: A hydrochloride that is the monohydrate of the dihydrochloride salt of cefepime. | [Synthesis]
At room temperature (15-25°C), 171g of sodium isocaproate (1.03 mol) was dissolved in 900mL of water and 200mL of acetone, and 300g of cefepime sulfate (0.52 mol, weight by weight in anhydrous) was added in batches with effective stirring to form a wel |
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