ChemicalBook--->CAS DataBase List--->126553-00-2

126553-00-2

126553-00-2 Structure

126553-00-2 Structure
IdentificationBack Directory
[Name]

6-Ethyl-3-pyridinamine
[CAS]

126553-00-2
[Synonyms]

6-Ethyl-3-pyridinamine
6-ethylpyridin-3-amine
2-Ethylpyridin-5-amine
3-Amino-6-ethylpyridine
5-Amino-2-ethylpyridine
3-Pyridinamine, 6-ethyl-
3-Pyridinamine,6-ethyl-(9CI)
6-Ethyl-3-pyridinamine ISO 9001:2015 REACH
[EINECS(EC#)]

604-596-9
[Molecular Formula]

C7H10N2
[MDL Number]

MFCD11111131
[MOL File]

126553-00-2.mol
[Molecular Weight]

122.17
Chemical PropertiesBack Directory
[Boiling point ]

244 °C
[density ]

1.037
[Fp ]

125 °C
[storage temp. ]

Keep in dark place,Inert atmosphere,Room temperature
[pka]

6.83±0.10(Predicted)
[Appearance]

Light yellow to brown Solid-Liquid Mixture
Safety DataBack Directory
[Safety Statements ]

24/25
[RIDADR ]

2810
[HazardClass ]

6.1
[PackingGroup ]

Ⅲ
[HS Code ]

29339900
Spectrum DetailBack Directory
[Spectrum Detail]

6-Ethyl-3-pyridinamine(126553-00-2)1HNMR
Hazard InformationBack Directory
[Synthesis]

Pyridine, 2-ethenyl-5-nitro- (9CI)

119836-85-0

6-Ethyl-3-pyridinamine

126553-00-2

The general procedure for the synthesis of 6-ethyl-3-aminopyridine from 5-nitro-2-vinylpyridine is as follows:[Ref. Example 66]; 5-Amino-2-ethylpyridine; 10% palladium-carbon catalyst (50% water moistened, 90 mg) was added to an ethanol solution (30 mL) of 5-nitro-2-vinylpyridine (450 mg), and the reaction was stirred under a hydrogen atmosphere at room temperature for 15 hours. Upon completion of the reaction, the catalyst was removed by filtration. Subsequently, the solvent was evaporated under reduced pressure to afford 6-ethyl-3-aminopyridine as an oily product (359 mg, 98% yield). The product was characterized by 1H-NMR (400 MHz, CDCl3): δ 1.25 (3H, t, J=7.5 Hz), 2.71 (2H, q, J=7.5 Hz), 3.32-3.78 (2H, br), 6.91-6.98 (2H, m), 8.02-8.05 (1H, m). Mass spectrum (ESI) m/z: 123 (M+H)+.

[References]

[1] Patent: EP1591443, 2005, A1. Location in patent: Page/Page column 53
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