| Chemical Properties | Back Directory | [Boiling point ]
593.3±45.0 °C(Predicted) | [density ]
1.082±0.06 g/cm3(Predicted) | [storage temp. ]
Storage temp. 2-8°C | [solubility ]
Soluble in DMSO, DCM, DMF | [form ]
Solid | [color ]
Light yellow to brown |
| Hazard Information | Back Directory | [Description]
Bis-propargyl-PEG12 has two alkyne groups at both ends of the linker. With the catalyzation of copper, the alkyne groups reacts with azide compounds to form stable triazole linkages. The PEG spacer enhances the water-solubility of the compound. | [Uses]
Bis-propargyl-PEG11 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Bis-propargyl-PEG11 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
|
| Company Name: |
Borenpharm Co., Ltd
|
| Telephone: |
027-65563561 13026317987; |
| Website: |
http://www.borenpharm.com |
| Company Name: |
Wuhan Topule
|
| Telephone: |
+86-02787215551 19945035818 |
| Website: |
http://www.topule.com/ |
| Company Name: |
Bide Pharmatech Ltd.
|
| Telephone: |
400-1647117 13681763483 |
| Website: |
https://www.bidepharm.com/ |
|