| Identification | Back Directory | [Name]
Propargyl-PEG6-t-butyl ester | [CAS]
1355197-95-3 | [Synonyms]
CAS_1355197-95-3
Propargyl-PEG6-Boc
Propargyl-PEG6-COOtBu
PropargylPEG6-tBu ester
Propargyl-P5-t-butyl ester
Propargyl-PEG6-t-butyl ester
4,7,10,13,16,19-Hexaoxadocos-21-ynoic acid, 1,1-dimethylethyl ester | [Molecular Formula]
C20H36O8 | [MDL Number]
MFCD28950777 | [MOL File]
1355197-95-3.mol | [Molecular Weight]
404.49 |
| Hazard Information | Back Directory | [Description]
Propargyl-PEG6-t-butyl ester is a heterobifunctional linker consisting of an alkyne group and a t-butyl protected carboxyl group. The alkyne group can participate in copper catalyzed azide-alkyne Click Chemistry to form a stable triazole linkage. The t-butyl group can be hydrolyzed under acidic conditions. | [Uses]
Propargyl-PEG6-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Propargyl-PEG6-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | [IC 50]
PEGs; Alkyl/ether | [References]
[1] Noah Bell, et al. Compounds and methods for inhibiting phosphate transport. WO2012054110A2. |
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Henan Alfachem Co.,Ltd.
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