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141732-76-5

141732-76-5 Structure

141732-76-5 Structure
IdentificationMore
[Name]

Exenatide acetate
[CAS]

141732-76-5
[Synonyms]

ENFUVIRTIDE ACETATE
EXENATIDE ACETATE
Exenatide
His-Gly-Gly-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH{2}
EXENATIDE ACETATE(EXENDIN-4)
[Molecular Formula]

C184H282N50O60S.C2H4O2
[MDL Number]

MFCD08704781
[MOL File]

141732-76-5.mol
[Molecular Weight]

4262.67
Hazard InformationBack Directory
[Chemical Properties]

White Solid
[Uses]

A 39-amino acid peptide originally isolated from the salivary glands of the Gila monster (Heloderma suspectum), differs from exendin-3 only in two positions close to the N-terminus. Application of exenatide causes an increase in acinar cAMP without stimulating amylase release. As an incretin mimetic, exenatide acts as agonist of the glucagon-like peptide-1 (GLP-1) receptor. As GLP-1, though with prolonged activity, exenatide augments the postprandial production of insulin and suppresses secretion of glucagon. For this reason, exenatide has found use as a medication of diabetes II.
Chemical PropertiesBack Directory
[CAS DataBase Reference]

141732-76-5(CAS DataBase Reference)
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