| Identification | More | [Name]
2,3-Dimethoxybenzoic acid | [CAS]
1521-38-6 | [Synonyms]
2,3-DIMETHOXYBENZOIC ACID
2-VERATRIC ACID
AKOS 233-29
DIMETHOXYBENZOIC ACID,2,3-
O-VERATRIC ACID
RARECHEM AL BO 0026
2,3-dimethoxy-benzoicaci
Benzoic acid, 2,3-dimethoxy-
DIMETHOXYBENZOIC ACID,2,3-(RG) | [EINECS(EC#)]
216-188-4 | [Molecular Formula]
C9H10O4 | [MDL Number]
MFCD00002432 | [Molecular Weight]
182.17 | [MOL File]
1521-38-6.mol |
| Chemical Properties | Back Directory | [Appearance]
LIGHT BEIGE FINE CRYSTALLINE POWDER | [Melting point ]
120-122 °C (lit.) | [Boiling point ]
275.56°C (rough estimate) | [density ]
1.2481 (rough estimate) | [refractive index ]
1.4500 (estimate) | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
5.310g/l slightly soluble | [form ]
Fine Crystalline Powder | [pka]
3.97±0.10(Predicted) | [color ]
Light beige | [Water Solubility ]
slightly soluble | [BRN ]
2210858 | [InChI]
InChI=1S/C9H10O4/c1-12-7-5-3-4-6(9(10)11)8(7)13-2/h3-5H,1-2H3,(H,10,11) | [InChIKey]
FODBVCSYJKNBLO-UHFFFAOYSA-N | [SMILES]
C(O)(=O)C1=CC=CC(OC)=C1OC | [LogP]
0.907 (est) | [CAS DataBase Reference]
1521-38-6(CAS DataBase Reference) | [NIST Chemistry Reference]
2,3-Dimethoxybenzoic acid(1521-38-6) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37/39:Wear suitable gloves and eye/face protection .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [RTECS ]
DG8598700
| [Hazard Note ]
Irritant | [HS Code ]
29189090 | [Toxicity]
mouse,LD50,intraperitoneal,> 800mg/kg (800mg/kg),Journal of Pharmacology and Experimental Therapeutics. Vol. 196, Pg. 478, 1976. |
| Raw materials And Preparation Products | Back Directory | [Raw materials]
1,2-Dimethoxybenzene-->Carbon dioxide-->Sodium-->Toluene | [Preparation Products]
methyl 2-(7-hydroxybenzofuran-3-yl)acetate-->2,3-DIMETHOXYANILINE-->6-Formyl-2,3-dimethoxybenzoic acid-->7-METHOXY-3(2H)-BENZOFURANONE-->1,3-BENZODIOXOLE-4-CARBOXYLIC ACID-->2,3,3',4'-TETRAMETHOXYBENZOPHENONE-->Hydrazine, (2,3-dimethoxyphenyl)--->2,3-DIMETHOXY-BENZOYL CHLORIDE |
| Hazard Information | Back Directory | [Chemical Properties]
LIGHT BEIGE FINE CRYSTALLINE POWDER | [Synthesis]
The general procedure for the synthesis of 2,3-dimethoxybenzoic acid from o-anisidine and carbon dioxide is as follows: an o-o-metalation reaction was carried out according to the method described in Example 1, using different substrates and CO2 as an electrophilic reagent. | [References]
[1] Angewandte Chemie - International Edition, 2002, vol. 41, # 2, p. 340 - 343
[2] Patent: US6384273, 2002, B1. Location in patent: Page column 9 |
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