| Identification | More | [Name]
2-Naphthyl acetate | [CAS]
1523-11-1 | [Synonyms]
2-NAPHTHYL ACETATE
ACETIC ACID 2-NAPHTHYL ESTER
ACETIC ACID NAPHTHALEN-2-YL ESTER
BETA-NAPHTHYL ACETATE
B-NAPHTHYL ACETATE
2-Acetoxynaphthalene
2-Naphthalenol, acetate
2-Naphthalenol,acetate
2-Naphthol, acetate
Acetic acid beta-naphthyl ester
beta-Naphthol acetate
Naphthalene, 2-acetoxy-
O-Acetyl-beta-naphthol
2-NAPTHYL ACETATE GR
b-NAPHTHYL ACETATE extrapure AR
Naphthalen-2-yl acetate
Acetic acid 2-naphthyl | [EINECS(EC#)]
216-194-7 | [Molecular Formula]
C12H10O2 | [MDL Number]
MFCD00004060 | [Molecular Weight]
186.21 | [MOL File]
1523-11-1.mol |
| Chemical Properties | Back Directory | [Appearance]
WHITE FLUFFY POWDER | [Melting point ]
67-70 °C (lit.) | [Boiling point ]
132 °C / 2mmHg | [density ]
1.1032 (rough estimate) | [refractive index ]
1.6010 (estimate) | [storage temp. ]
−20°C
| [solubility ]
methanol: 0.1 g/mL, clear
| [form ]
powder to crystaline | [color ]
White to Light yellow | [Sensitive ]
Moisture Sensitive | [BRN ]
1868291 | [InChI]
1S/C12H10O2/c1-9(13)14-12-7-6-10-4-2-3-5-11(10)8-12/h2-8H,1H3 | [InChIKey]
RJNPPEUAJCEUPV-UHFFFAOYSA-N | [SMILES]
CC(=O)Oc1ccc2ccccc2c1 | [CAS DataBase Reference]
1523-11-1(CAS DataBase Reference) | [NIST Chemistry Reference]
2-Naphthyl acetate(1523-11-1) | [EPA Substance Registry System]
1523-11-1(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R41:Risk of serious damage to eyes. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S39:Wear eye/face protection . | [WGK Germany ]
3
| [F ]
10-21 | [TSCA ]
Yes | [HS Code ]
2916399090 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Eye Dam. 1 |
| Hazard Information | Back Directory | [Chemical Properties]
WHITE FLUFFY POWDER | [Uses]
2-Naphthyl acetate has been used as a substrate:
- in substrate sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) to examine the composition of lipases in larvae and adult specimens
- in the preparation of zymograms to identify proteins with lipase activity
- to measure non-specific esterase activity and β-esterase enzyme activity
| [Uses]
2-Naphthyl Acetate is used in the staining of gels for esterase activity in the biological laboratories. An esterase substrate. | [Synthesis Reference(s)]
Journal of the American Chemical Society, 91, p. 2162, 1969 DOI: 10.1021/ja01036a081 | [Biological Activity]
2-Naphthyl acetate/β-naphthyl acetate (BNA) is an ester substrate. It can be used in staining gels to detect esterase activity. BNA dissolved in acetone and ethanol produces a dark and very light/no background respectively. Hence destaining is not necessary if ethanol is used to dissolve BNA for esterase staining of gels. | [Purification Methods]
Distil the acetate in a high vaccum and/or crystallise it from pet ether (b 60-80o) or dilute aqueous EtOH. The picrate has m 80o (from EtOH). [Beilstein 6 H 644, 6 I 313, 6 II 600, 5 III 2982, 6 IV 4267.] |
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