| Identification | More | [Name]
Cartap | [CAS]
15263-53-3 | [Synonyms]
2-dimethylamino-1,3-bis(carbamoylthio)propane
carbamicacid,thio-,s,s’-(2-(dimethylamino)trimethylene)ester
carbamothioicacid,s,s’-(2-(dimethylamino)-1,3-propanediyl)ester
s,s’-(2-(dimethylamino)-1,3-propanediyl)dicarbamothioate
sanvex
t-1258
thiobel
CARTAP 98%TC
SS2DIMETHYLAMINO13PROPANEDIYLDITHIOCARBAMATE
Cartap
S,S'-2-Dimethylaminopropane-1,3-diyl (dithiocarbamate)
cartap 1,3-bis(carbamoylthio)-2-(dimethylamino)propane
[2-(Dimethylamino)propane-1,3-diyl]bis(thio)bisformamide
1,3-Bis(carbamoylthio)-2-(dimethylamino)propane
TL-1258 | [EINECS(EC#)]
620-418-2 | [Molecular Formula]
C7H15N3O2S2 | [MDL Number]
29302000 | [Molecular Weight]
237.343 | [MOL File]
15263-53-3.mol |
| Safety Data | Back Directory | [Hazard Codes ]
N | [Risk Statements ]
R50/53:Very Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment . | [Safety Statements ]
S60:This material and/or its container must be disposed of as hazardous waste .
S61:Avoid release to the environment. Refer to special instructions safety data sheet . | [HS Code ]
29302000 | [Toxicity]
mouse,LD50,oral,92mg/kg (92mg/kg),Agricultural and Biological Chemistry. Vol. 34, Pg. 935, 1970. |
| Hazard Information | Back Directory | [Chemical Properties]
solid | [Uses]
Cartap is obtained by hydrolyzing 1,1-dithiocyanato-
2-dimethylaminopropane with hydrochloric acid. Cartap
is the pro-insecticide of the natural toxin nereistoxin. It
is used for the control of chewing and sucking insects, at almost all stages of development, on many crops. Its
structure is based on that of the naturally occurring neurotoxin,
nereistoxin. | [Definition]
ChEBI: Cartap is a nereistoxin analogue insecticide. | [Metabolism]
Cartap is hydrolyzed in base to the dihydronereistoxin,
which is oxidized to the insecticide, nereistoxin
(32). The conversion occurs within plants, and the
monoxide (33)was identified as aminor metabolite. In rats,
cartap was rapidly excreted in urine. It was hydrolyzed,
converted to the sulfoxide, and N-demethylated (9). | [Toxicity evaluation]
Nereistoxin does not inhibit cholinesterase. Instead, it
acts as an antagonist at the nicotinic acetylcholine receptor
and blocks neural transmission (10). |
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