| Identification | More | [Name]
Mepivacaine hydrochloride | [CAS]
1722-62-9 | [Synonyms]
1-methyl-2',6'-pipecoloxylidine hydrochloride
1-METHYL-2',6'-PIPECOLOXYLIDINE HYDROCHLORIDE SALT
LABOTEST-BB LT00134661
MEPIVACAINE
MEPIVACAINE HCL
MEPIVACAINE HYDROCHLORIDE
n-(2,6-dimethylphenyl)-1-methyl-2-piperidinecarboxamide hydrochloride
N-(2,6-DIMETHYLPHENYL)-1-METHYL-2-PIPERIDINECARBOXAMIDE HYDROCHLORIDE SALT
(1-methyl-dl-piperidine-2-carboxylicacid)-2,6-dimethylanilidehydrochloride
1-methyl-2’,6’-pipecoloxylididehydrochloride
6’-pipecoloxylidide,1-methyl-2monohydrochloride
carbocainehydrochloride
dl-1-methyl-2’,6’-pipecoloxylididehydrochloride
dl-mepivacainehydrochloride
n-(2,6-dimethylphenyl)-1-methyl-2-piperidinecarboxamidmonohydrochloride
MEPIVACAINE HYDROCHLORIDE, USP
Mepivacaine HCl USP
2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-methyl-, monohydrochloride
2',6'-Pipecoloxylidide, 1-methyl-, monohydrochloride (6CI, 8CI)
2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-methyl-, monohydrochloride (9CI) | [EINECS(EC#)]
217-023-9 | [Molecular Formula]
C15H22N2O | [MDL Number]
MFCD00243006 | [Molecular Weight]
246.35 | [MOL File]
1722-62-9.mol |
| Chemical Properties | Back Directory | [Melting point ]
255-257°C (dec.) | [storage temp. ]
2-8°C | [solubility ]
H2O: soluble20mg/mL, clear | [form ]
powder | [color ]
white to beige | [Water Solubility ]
H2O: 20mg/mL, clear | [InChI]
InChI=1S/C15H22N2O.ClH/c1-11-7-6-8-12(2)14(11)16-15(18)13-9-4-5-10-17(13)3;/h6-8,13H,4-5,9-10H2,1-3H3,(H,16,18);1H | [InChIKey]
RETIMRUQNCDCQB-UHFFFAOYSA-N | [SMILES]
C1(=C(C)C=CC=C1C)NC(=O)C1CCCCN1C.Cl | [CAS DataBase Reference]
1722-62-9(CAS DataBase Reference) | [EPA Substance Registry System]
1722-62-9(EPA Substance) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS06 | [Signal word ]
Danger | [Hazard statements ]
H301-H336 | [Precautionary statements ]
P261-P264-P270-P271-P301+P310-P304+P340+P312 | [Hazard Codes ]
Xn | [Risk Statements ]
R22:Harmful if swallowed. | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes . | [RIDADR ]
UN 2811 6.1 / PGIII | [WGK Germany ]
WGK 3 | [RTECS ]
TK6475000 | [TSCA ]
TSCA listed | [HS Code ]
29333990 | [Storage Class]
6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | [Hazard Classifications]
Acute Tox. 3 Oral
STOT SE 3 | [Safety Profile]
skin irritant. Questionable carcinogen with | [Toxicity]
LD50 in mice, rats (mg/kg): 280, 500 s.c. (Aberg) |
| Hazard Information | Back Directory | [Chemical Properties]
White Solid | [Uses]
An anti-inflammatory and analgesic | [Uses]
anesthetic (local) | [Definition]
ChEBI: The hydrochloride salt of mepivacaine. It is used as a local anaesthetic. | [Brand name]
Arestocaine Hydrochloride (Solvay Pharmaceuticals); Carbocaine (Hospira); Isocaine Hydrochloride(Novocol); Polocaine (AstraZeneca); Polocaine (Dentsply); Scandonest (Deproco). | [Biological Functions]
Mepivacaine hydrochloride (Carbocaine) is longer
acting than lidocaine and has a more rapid onset of action
(3–5 minutes). Topical application is not effective.
It has been widely used in obstetrics, but its use has declined
recently because of the early transient neurobehavioral
effects it produces. Adverse reactions associated
with mepivacaine are generally similar to those
produced by other local anesthetics. It can be used with
epinephrine or levonordefrin (dental use only). | [General Description]
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Mepivacaine hydrochloride is a local anesthetic that is related chemically and pharmacologically to the amide-type local anesthetics. It is often administered via local infiltration, peripheral nerve block, etc. | [Biochem/physiol Actions]
Local anesthetic. Reversibly blocks transient Na+ inward current, as well as the steady-state K+ outward current. Blocks tandem pore (TASK) and Kv1.5, potassium channels in model systems. |
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