| Identification | More | [Name]
3-Pyridineethaneamine | [CAS]
20173-24-4 | [Synonyms]
2-(3-PYRIDYL)ETHYLAMINE
2-(PYRIDIN-3-YL)ETHANAMINE
2-PYRIDIN-3-YL-ETHYLAMINE
3-(2-AMINOETHYL)PYRIDINE
3-AMINOETHYLPYRIDINE
RARECHEM AL BW 0249
Aminoethylpyridine
3-pyridineethaneamine
2-Pyridin-3-yl-ethylamine hydrochloride
2-pyridin-3-ylethanamine dihydrochloride | [EINECS(EC#)]
671-720-6 | [Molecular Formula]
C7H10N2 | [MDL Number]
MFCD00191604 | [Molecular Weight]
122.17 | [MOL File]
20173-24-4.mol |
| Chemical Properties | Back Directory | [Boiling point ]
119-120°C 19mm | [density ]
1.04 | [refractive index ]
1.5518 | [Fp ]
119-120°C/19mm | [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [form ]
clear liquid | [pka]
9.29±0.10(Predicted) | [color ]
Colorless to Almost colorless | [Specific Gravity]
1.04 | [Water Solubility ]
Slightly soluble in water. | [Sensitive ]
Air Sensitive | [BRN ]
111288 | [CAS DataBase Reference]
20173-24-4(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R34:Causes burns. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [RIDADR ]
2735 | [WGK Germany ]
3 | [HazardClass ]
8 | [PackingGroup ]
III | [HS Code ]
29333990 |
| Hazard Information | Back Directory | [Chemical Properties]
Colorless liquid | [Uses]
3-(2-Aminoethyl)pyridine has been used in the synthesis of urea. | [Synthesis]
The general procedure for the synthesis of 3-(2-aminoethyl)pyridine from 3-pyridylacetonitrile was as follows: 2-(pyridin-3-yl)acetonitrile (1 g, 8.47 mmol, 1.00 eq.), nickel ryenne (1 g, 17.24 mmol, 1.00 eq.) and ammonium hydroxide (3 mL) were dissolved in methanol (15 mL). The mixture was stirred and reacted overnight at room temperature and 1 atm hydrogen atmosphere. Upon completion of the reaction, the catalyst was removed by filtration through a diatomaceous earth pad and washed several times with methanol. The filtrate and washings were combined and concentrated in vacuum to give 940 mg (45% yield) of 2-(pyridin-3-yl)ethylamine as a yellow oil.LC-MS analysis: (ES, m/z): 164 [M + CH3CN + H]+, 123 [M + H]+, 106. | [References]
[1] Patent: WO2013/155338, 2013, A2. Location in patent: Page/Page column 180
[2] Patent: US2015/329503, 2015, A1. Location in patent: Paragraph 0720; 0721
[3] Patent: US6017919, 2000, A
[4] Journal of the American Chemical Society, 1980, vol. 102, # 17, p. 5530 - 5538
[5] Journal of the American Chemical Society, 1955, vol. 77, p. 6554,6556 |
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