| Identification | More | [Name]
5-Amino-8-quinolinol dihydrochloride | [CAS]
21302-43-2 | [Synonyms]
5-AMINO-8-HYDROXYQUINOLINE DIHYDROCHLORIDE
5-AMINO-8-QUINOLINOL DIHYDROCHLORIDE
5-Amino-8-hydroquinoline dihydrochloride
5-Amino-8-hydroxyquinoline2HCl
8-Quinolinol, 5-amino-, dihydrochloride
5-AMINO-8-HYDROXYQUINOLINE DIHYDROCHLORIDE 97+% | [Molecular Formula]
C9H10Cl2N2O | [MDL Number]
MFCD00012737 | [Molecular Weight]
233.09 | [MOL File]
21302-43-2.mol |
| Chemical Properties | Back Directory | [Melting point ]
279 °C (dec.)(lit.) | [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [form ]
powder to crystal | [color ]
Orange to Amber to Dark red | [Water Solubility ]
almost transparency | [InChI]
1S/C9H8N2O.2ClH/c10-7-3-4-8(12)9-6(7)2-1-5-11-9;;/h1-5,12H,10H2;2*1H | [InChIKey]
VTQDJAUGGZFPOI-UHFFFAOYSA-N | [SMILES]
Cl[H].Cl[H].Nc1ccc(O)c2ncccc12 | [CAS DataBase Reference]
21302-43-2(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37/39:Wear suitable gloves and eye/face protection .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [HS Code ]
29334900 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Hazard Information | Back Directory | [Chemical Properties]
Crystalline powder | [Uses]
5-Amino-8-hydroxyquinoline dihydrochloride was used in synthesis of:
- 5-acetamido-8-hydroxyquinoline hydrochloride
- 5-(p-tolylsulfonylimino)quinolin-8-one
- 5,8-quinolinesemiquinone via ferric chloride oxidation
| [Synthesis]
Step 1: Preparation of 5-nitroso-8-hydroxyquinoline hydrochlorideA solution of NaNO2 (30 g) in water (100 ml) was added to a mixture of 8-hydroxyquinoline (58 g, 0.4 mol) in distilled water, concentrated hydrochloric acid (75 ml) and ice (200 g) at 0-4 |
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