ChemicalBook--->CAS DataBase List--->2133-34-8

2133-34-8

2133-34-8 Structure

2133-34-8 Structure
IdentificationMore
[Name]

(S)-(-)-2-Azetidinecarboxylic acid
[CAS]

2133-34-8
[Synonyms]

(2S)-(-)-AZETIDINE-2-CARBOXYLIC ACID
H-AZE(2)-OH
H-AZE-OH
L-2-AZETIDINECARBOXYLIC ACID
L-AZETIDINE-2-CARBOXYLIC ACID
L-AZETIDINECARBOXYLIC ACID
L-TRIMETHYLENEIMINE-2-CARBOXYLIC ACID
(S)-(-)-2-AZETIDINECARBOXYLIC ACID
(S)-2-AZETIDINE CARBOXYLIC ACID
(S)-(-)-AZETIDINE-2-CARBOXYLIC ACID
(S)-AZETIDINE-2-CARBOXYLIC ACID
(S)-L-2-AZETIDINE CARBOXYLIC ACID
(s)-2-azetidinecarboxylicaci
acidel-azetidine-2-carboxylic
acidel-azetidine-2-carboxylic(french)
l-2-azetidinecarboxylicaci
l-azetidine-2-carboxylicaci
L-AZETIDINE-2-CARBOXYLIC ACID*CRYSTALLIN E
(S)-(-)-2-AZETIDINECARBOXYLIC ACID, 99+%
(S)-(-)-2-Azetidinecarboxylic
[EINECS(EC#)]

218-362-5
[Molecular Formula]

C4H7NO2
[MDL Number]

MFCD00005166
[Molecular Weight]

101.1
[MOL File]

2133-34-8.mol
Chemical PropertiesBack Directory
[Appearance]

white to light yellow crystal powder
[Melting point ]

~215 °C (dec.)
[alpha ]

-125 º (c=1, water 25 ºC)
[Boiling point ]

189.47°C (rough estimate)
[density ]

1.2245 (rough estimate)
[refractive index ]

-122 ° (C=4, H2O)
[storage temp. ]

2-8°C
[solubility ]

Aqueous Base (Slightly), Methanol (Slightly), Water (Slightly)
[form ]

Crystalline Powder or Crystals
[pka]

2.35±0.20(Predicted)
[color ]

White to light beige
[Water Solubility ]

5 g/100 mL
[Usage]

A four-membered ring analog of L-Proline. A useful intermediate in the synthesis of polypeptides
[Merck ]

14,908
[BRN ]

80678
[InChIKey]

IADUEWIQBXOCDZ-VKHMYHEASA-N
[CAS DataBase Reference]

2133-34-8(CAS DataBase Reference)
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
[Hazard Codes ]

Xi
[Risk Statements ]

R36/37/38:Irritating to eyes, respiratory system and skin .
[Safety Statements ]

S24/25:Avoid contact with skin and eyes .
S36:Wear suitable protective clothing .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
[WGK Germany ]

3
[RTECS ]

CM4310500
[Hazard Note ]

Irritant
[HS Code ]

29339900
[Hazardous Substances Data]

2133-34-8(Hazardous Substances Data)
[Toxicity]

LD50 scu-mus: 1000 mg/kg 85GDA2 8(1),101,82
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Hydrochloric acid-->Ethyl acetate-->Methanol-->Diethyl ether-->Tetrahydrofuran-->Dichloromethane-->Thionyl chloride-->Petroleum ether-->Potassium carbonate-->Sodium bicarbonate-->Palladium-->Ammonium chloride-->Acetonitrile-->Dimethyl sulfoxide-->Potassium tert-butoxide-->L-1-Phenylethylamine-->2-Bromoethanol-->Bromoacetonitrile
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

L-2-Azetidinecarboxylic acid(2133-34-8).msds
Hazard InformationBack Directory
[Chemical Properties]

white to light yellow crystal powder
[Uses]

(S)-(-)-2-Azetidinecarboxylic acid is a four-membered ring analog of L-Proline, It is a useful intermediate in the synthesis of polypeptides,Used in synthesis of abnormally high molecular weight polypeptides.
[Uses]

Specific proline antagonist. Used in synthesis of abnormally high molecular weight polypeptides.
[Definition]

ChEBI: The (S)-enantiomer of azetidine-2-carboxylic acid.
[General Description]

L-Azetidine-2-carboxylic acid is a non-protein amino acid and teratogenic agent. It is toxic in nature.
[Biochem/physiol Actions]

Azetidine-2-carboxylic acid (AZC) triggers protein aggregation or upregulates the expression of an aggregation-prone mutant protein, upon interference with nascent protein folding.
[Safety Profile]

Moderately toxic by subcutaneousroute. An experimental teratogen. Other experimentalreproductive effects. When heated to decomposition itemits toxic fumes of NOx.
[storage]

Store at -20°C
Spectrum DetailBack Directory
[Spectrum Detail]

(S)-(-)-2-Azetidinecarboxylic acid(2133-34-8)1HNMR
(S)-(-)-2-Azetidinecarboxylic acid(2133-34-8)FT-IR
(S)-(-)-2-Azetidinecarboxylic acid(2133-34-8)IR
(S)-(-)-2-Azetidinecarboxylic acid(2133-34-8)Raman
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

(S)-(-)-2-Azetidinecarboxylic acid, 99+%(2133-34-8)
[Alfa Aesar]

(S)-(-)-Azetidine-2-carboxylic acid, 99%(2133-34-8)
[Sigma Aldrich]

2133-34-8(sigmaaldrich)
[TCI AMERICA]

L-Azetidine-2-carboxylic Acid  [Antagonist of L-Proline],>98.0%(T)(2133-34-8)
2133-34-8 suppliers list
Company Name: Shanghai Mixiu Chemical Co., Ltd.  Gold
Telephone: 18101936766
Website: http://www.shmychem.com
Company Name: Wuhan Chuangshuo Chemical Technology Co., Ltd  Gold
Telephone: 180-62205282 18062205282
Website: www.chemicalbook.com/supplier/134320673/
Company Name: Shanghai Binma Technology Co., Ltd.  Gold
Telephone: 15262241608
Website:
Company Name: J & K SCIENTIFIC LTD.  
Telephone: 18210857532 18210857532
Website: https://www.jkchemical.com
Company Name: Meryer (Shanghai) Chemical Technology Co., Ltd.  
Telephone: 4006356688 18621169109
Website: www.x-labseek.com/
Company Name: 3B Pharmachem (Wuhan) International Co.,Ltd.  
Telephone: 18930552037
Website: www.chemicalbook.com/showsupplierproductslist13285/0_en.htm
Company Name: Alfa Aesar  
Telephone: 400-6106006
Website: http://chemicals.thermofisher.cn
Company Name: TCI (Shanghai) Development Co., Ltd.  
Telephone: 021-67121386
Website: https://www.tcichemicals.com/CN/zh/
Company Name: Capot Chemical Co., Ltd  
Telephone: +86 (0) 571 85 58 67 18
Website: www.capotchem.com
Company Name: JinYan Chemicals(ShangHai) Co.,Ltd.  
Telephone: 13817811078
Website: www.jingyan-chemical.com
Company Name: Accela ChemBio Co.,Ltd.  
Telephone: 021-50795510 4000665055
Website: http://www.shao-yuan.com/
Company Name: Shanghai Longsheng chemical Co.,Ltd.  
Telephone: 58099637 13585536065
Website: www.shlshg.com
Company Name: Shanghai Hanhong Scientific Co.,Ltd.  
Telephone: 021-54306202 13764082696
Website: https://www.hanhongsci.com
Company Name: Chemsky(shanghai)International Co.,Ltd.  
Telephone: 021-50135380
Website: www.shchemsky.com
Company Name: China DongFan Chemical Co.,LTD  
Telephone: 86-0571-85151182
Website: www.chemicalbook.com/ShowSupplierProductsList14819/0_EN.htm
Company Name: Shanghai Aobo pharmaceutical Technology Co., Ltd  
Telephone: 86-21-51320499
Website: www.chemicalbook.com/ShowSupplierProductsList4808/0_EN.htm
Company Name: Sichuan Kulinan Technology Co., Ltd  
Telephone: 400-1166-196 18981987031
Website: http://www.hx-r.com/
Company Name: China Langchem Inc.  
Telephone: 0086-21-58956006
Website: www.chemicalbook.com/ShowSupplierProductsList19141/0_EN.htm
Tags:2133-34-8 Related Product Information
36476-78-5 89-00-9 503-29-7 106-97-8 18559-94-9 513-36-0 3737-95-9 51022-70-9 2516-34-9 77-92-9 100-26-5 75-28-5 503-30-0 51077-14-6 102-82-9 18621-18-6 142253-55-2 928038-44-2