| Identification | More | [Name]
L-Menthol | [CAS]
2216-51-5 | [Synonyms]
(1alpha,2beta,5alpha)-5-methyl-2-(1-methylethyl)-cyclohexanol
1-P-MENTHAN-3-OL
(1R,2S,5R)-(-)-2-ISOPROPYL-5-METHYLCYCLOHEXANOL
(1R,2S,5R)-2-ISOPROPYL-5-METHYLCYCLOHEXANOL
(1R,2S,5R)-(-)-MENTHOL
(1R,2S,5R)-MENTHOL
3-P-METHANOL
5-METHYL-2-(1-METHYLETHYL)CYCLOHEXANOL
FEMA 2665
L-2-ISOPROPYL-5-METHYLCYCLOHEXANOL
L-4-MENTHAN-3-OL
LEVO-MENTHOL
LEVOMENTHOLUM
L-MENTHAN-3-OL
(-)-L-MENTHOL
L(-)-MENTHOL
L-MENTHOL
L-MENTHOL (NATURAL)
L-P-MENTHAN-3-OL
(-)-MENTHOL | [EINECS(EC#)]
218-690-9 | [Molecular Formula]
C10H20O | [MDL Number]
MFCD00062979 | [Molecular Weight]
156.27 | [MOL File]
2216-51-5.mol |
| Chemical Properties | Back Directory | [Appearance]
white to light yellow crystal powde | [Melting point ]
41-45 °C (lit.) | [alpha ]
-51 º (589nm, c=10, EtOH) | [Boiling point ]
212 °C (lit.) | [density ]
0.89 g/mL at 25 °C(lit.)
| [vapor pressure ]
0.8 mm Hg ( 20 °C)
| [FEMA ]
2665 | [refractive index ]
1.46
| [Fp ]
200 °F
| [storage temp. ]
−20°C
| [solubility ]
490mg/l | [form ]
Crystals or Crystalline Needles | [pka]
15.30±0.60(Predicted) | [color ]
Colorless to white | [Specific Gravity]
0.89 | [Stability:]
Stable. | [optical activity]
[α]22/D 49°, c = 10 in 95% ethanol | [Water Solubility ]
insoluble | [Detection Methods]
GC,NMR,Rotation | [Merck ]
14,5837 | [BRN ]
1902293 | [InChIKey]
NOOLISFMXDJSKH-KXUCPTDWSA-N | [CAS DataBase Reference]
2216-51-5(CAS DataBase Reference) | [NIST Chemistry Reference]
Cyclohexanol, 5-methyl-2-(1-methylethyl)-, [1R-(1«alpha»,2«beta»,5«alpha»)]-(2216-51-5) | [EPA Substance Registry System]
2216-51-5(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R37/38:Irritating to respiratory system and skin .
R41:Risk of serious damage to eyes.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S39:Wear eye/face protection .
S37/39:Wear suitable gloves and eye/face protection .
S36:Wear suitable protective clothing . | [WGK Germany ]
2
| [RTECS ]
OT0700000
| [TSCA ]
Yes | [HS Code ]
29061100 | [Safety Profile]
Poison by intravenous
route. Moderately toxic by ingestion,
intraperitoneal, and subcutaneous routes. An
eye irritant. Mutation data reported. When
heated to decomposition it emits acrid
smoke and irritating fumes. | [Hazardous Substances Data]
2216-51-5(Hazardous Substances Data) | [Toxicity]
LD50 orally in Rabbit: 3300 mg/kg LD50 dermal Rabbit > 5000 mg/kg |
| Hazard Information | Back Directory | [Chemical Properties]
white to light yellow crystal powde | [Uses]
(1R,2S,5R)-(-)-Menthol (L-Menthol) is the natural form of Menthol. L-Menthol is used as: refreshing agent, food flavor,
cool and antipruritic drug, carminative drug. Menthol crystals is used for pers
onal care and cosmetics. | [Uses]
analgesic (topical), antipruritic agent | [Definition]
ChEBI: A p-menthan-3-ol which has (1R,2S,5R)-stereochemistry. It is the most common naturally occurring enantiomer. | [General Description]
Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate. | [Flammability and Explosibility]
Nonflammable | [Biochem/physiol Actions]
Taste at 25 ppm | [Purification Methods]
Crystallise menthol from CHCl3,pet ether or EtOH/water. [Barrow & Atkinson J Chem Soc 638 1939, Beilstein 6 III 133, 6 IV 150.] |
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