| Identification | More | [Name]
2-Bromo-6-fluorobenzoic acid | [CAS]
2252-37-1 | [Synonyms]
1-(4'-IODOPHENYL)BUTANE
1-BUTYL-4-IODOBENZENE
1-N-BUTYL-4-IODOBENZENE
2-BROMO-6-FLUOROBENZOIC ACID
2-FLUORO-6-BROMOBENZOIC ACID
4-N-BUTYLIODOBENZENE
BUTTPARK 24\01-96
P-BUTYLIODOBENZENE
6-Bromo-2-Fluorobenzoic Acid 2-Fluoro-6-Bromobenzoic Acid
6-Bromo-2-Fluorobenzoic Acid
2-Bromo-6-fluorobenzoic
2-fluoro-6-bromobenzonic acid | [EINECS(EC#)]
207-259-0 | [Molecular Formula]
C7H4BrFO2 | [MDL Number]
MFCD00051927 | [Molecular Weight]
219.01 | [MOL File]
2252-37-1.mol |
| Chemical Properties | Back Directory | [Melting point ]
153-155°C | [Boiling point ]
286.1±25.0 °C(Predicted) | [density ]
1.789±0.06 g/cm3(Predicted) | [refractive index ]
1.567-1.569
| [storage temp. ]
Sealed in dry,Room Temperature | [form ]
Solid | [pka]
1.92±0.10(Predicted) | [color ]
White to Light yellow to Light orange | [InChI]
InChI=1S/C7H4BrFO2/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H,10,11) | [InChIKey]
MDAZJVAIZVUWDE-UHFFFAOYSA-N | [SMILES]
C(O)(=O)C1=C(F)C=CC=C1Br | [CAS DataBase Reference]
2252-37-1(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S37/39:Wear suitable gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [RIDADR ]
2811 | [WGK Germany ]
3 | [Hazard Note ]
Irritant | [HazardClass ]
IRRITANT | [PackingGroup ]
Ⅲ | [HS Code ]
29163990 |
| Hazard Information | Back Directory | [Chemical Properties]
White powder | [Uses]
2-Bromo-6-fluorobenzoic acid is an intermediate, mainly used in the industries such as medicine, agricultural chemicals at present. | [Synthesis]
The synthesis and preparation method of the 2-bromo-6-fluorobenzoic acid comprises the following steps: by using o-fluorobenzonitrile as an initial raw material, carrying out nitrification, nitroreduction, bromization, diazo-deamination and hydrolysis to synthesize the 2-bromo-6-fluorobenzoic acid. | [References]
[1] Organic Letters, 2009, vol. 11, # 5, p. 1051 - 1054
[2] Australian Journal of Chemistry, 2016, vol. 69, # 3, p. 307 - 313
[3] Synthesis, 2005, # 4, p. 617 - 621
[4] Tetrahedron Letters, 1996, vol. 37, # 36, p. 6551 - 6554
[5] ChemMedChem, 2010, vol. 5, # 10, p. 1693 - 1696 |
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