| Identification | Back Directory | [Name]
Fluopicolide | [CAS]
239110-15-7 | [Synonyms]
infinito
Fluopicolide
Fluopicolide 0
Fluopicolide [iso]
Fluopicolide Standard
Fluopicolide Solution, 1000ppm
Fluopicolide@100 μg/mL in Acetone
Fluopicolide@100 μg/mL in Acetonitrile
Fluopicolide@1000 μg/mL in Acetonitrile
Fluopicolide Solution in Methanol in Acetonitrile, 1000μg/mL
2,6-Dichloro-N-[3-chloro-5-(trifluoromethyl)-2-pyridylmethyl]benzamide
2,6-Dichloro-N-((3-chloro-5-(trifluoroMethyl)pyridin-2-yl)Methyl)benzaMide
2,6-Dichloro-N-[[3-chloro-5-(trifluoro-methyl)-2-pyridinyl]methyl]benzamide
BenzaMide,2,6-dichloro-N-[[3-chloro-5-(trifluoroMethyl)-2-pyridinyl]Methyl]- | [EINECS(EC#)]
259-565-9 | [Molecular Formula]
C14H8Cl3F3N2O | [MDL Number]
MFCD09751509 | [MOL File]
239110-15-7.mol | [Molecular Weight]
383.58 |
| Chemical Properties | Back Directory | [Melting point ]
150 °C | [Boiling point ]
432.1±45.0 °C(Predicted) | [density ]
1.515±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly, Sonicated) | [form ]
Solid | [pka]
11.14±0.46(Predicted) | [color ]
Off-White to Light Yellow | [Henry's Law Constant]
9.0×103 mol/(m3Pa) at 25℃, HSDB (2015) | [Major Application]
agriculture
environmental | [InChI]
1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23) | [InChIKey]
GBOYJIHYACSLGN-UHFFFAOYSA-N | [SMILES]
FC(F)(F)c1cnc(CNC(=O)c2c(Cl)cccc2Cl)c(Cl)c1 | [LogP]
3.820 (est) | [EPA Substance Registry System]
Benzamide, 2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]methyl]- (239110-15-7) |
| Hazard Information | Back Directory | [Description]
Fluopicolide is a fungicide used for the control of a range of Oomycete diseases including downy mildew and blight. It has a low aqueous solubility and is not highly volatile. It tends to be fairly persistent in most soil systems and stable in water-sediment systems. There is also a risk of it leaching to groundwater. No significant risks to human health have been identified. It is moderately toxic to most biodiversity but there is less of a risk to bees. | [Uses]
Fluopicolide is a useful chemical that kills oomycetes in vitro. | [Definition]
ChEBI: A member of the class of benzamides obtained by formal condensation of the carboxy group of 2,6-dichlorobenzoic acid with the amino group of [3-chloro-5-(trifluoromethyl)pyridin-2-yl]methylamine. A fungicide used for the control of a range of diseases incl
ding downy mildew and blight. | [Production Methods]
Fluopicolide is commercially produced through a multi-step chemical synthesis that constructs its acylpicolide structure, designed for high efficacy against oomycete pathogens. The process begins with the chlorination of benzene derivatives to form a 2,6-dichlorobenzamide core. This is then coupled via an amide bond with a substituted pyridine ring bearing a trifluoromethyl group and an additional chlorine atom. The key intermediate—3-chloro-5-(trifluoromethyl)pyridin-2-ylmethylamine—is synthesized separately and reacted with the benzoyl chloride derivative under controlled conditions to yield the final active ingredient: 2,6-dichloro-N-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}benzamide. | [Agricultural Uses]
Fungicide: Fluopicolide is targeted for control of oomycete fungal diseases on turf, ornamentals, and several food uses
including grapes and six crop groupings (leafy vegetables,
fruiting vegetables, brassica vegetables, root and tuber
vegetables, bulb vegetables, and cucurbits) that may be
grown throughout the U.S [83] . | [Trade name]
INFINITO®, Bayer; PRECIDIO | [Mechanism of action]
Protectant, novel mode of action as fluopicolide delocalises spectrin-like proteins | [Pesticide Type]
Fungicide |
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