| Identification | More | [Name]
Antazoline hydrochloride | [CAS]
2508-72-7 | [Synonyms]
2-(N-BENZYLANILINOMETHYL)-2-IMIDAZOLINE HYDROCHLORIDE
2-(N-BENZYLANILINOMETHYL) IMIDAZOLINE HYDROCHLORIDE
2-(N-PHENYL-N-BENZYL-AMINOMETHYL)-IMIDAZOLINE HCL
4,5-DIHYDRO-N-PHENYL-N-(PHENYLMETHYL)-1H-IMIDAZOLE-2-METHANAMINE HYDROCHLORIDE
ANTAZOLINE HCL
ANTAZOLINE HYDROCHLORIDE
BENZYL-(4,5-DIHYDRO-1H-IMIDAZOL-2-YLMETHYL)-PHENYL-AMINE HCL
LABOTEST-BB LT00134672
N-BENZYL-N-(2-IMIDAZOLIN-2-YLMETHYL)ANILINE HYDROCHLORIDE
2-((n-benzylanilino)methyl)-2-imidazolinhydrochloride
2-((n-benzylanilino)methyl)-2-imidazolinmonohydrochloride
2-(n-phenyl-n-benzylaminomethyl)imidazolinehydrochloride
2-phenylbenzylaminomethylimidazolinehydrochloride
antistinehydrochloride
fenazolina
histazine
Antazolin Hcl
2-(N-Benzyl-N-phenylaminonomethyl)-2-imidazoline
N-BENZYL-N-(2-IMIDAZOLIN-2-YLMETHY)ANILINE
2-Phenyl-benzyl-amino-methylimidazolin hydrochloride | [EINECS(EC#)]
219-719-8 | [Molecular Formula]
C17H20ClN3 | [MDL Number]
MFCD00058145 | [Molecular Weight]
301.81 | [MOL File]
2508-72-7.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [RTECS ]
NJ2150000
| [HS Code ]
2933.29.4300 |
| Hazard Information | Back Directory | [Chemical Properties]
White or almost white crystalline powder | [Originator]
Antistine HCl,Ciba,US,1948 | [Uses]
Antazoline Hydrochloride acts as a histamine H1 receptor blocker, functioning as an antihistamine pharmaceutical. | [Uses]
Antihistaminic;H1 antagonist | [Uses]
Imidazoline binding site ligand and an antihistamine | [Manufacturing Process]
15.4 parts of 2-chloromethylimidazoline hydrochloride, 45.8 parts of Nbenzylaniline
and 150 parts of alcohol are heated in an oil bath at 100° to
110°C. After distilling off the alcohol, the reaction mass is maintained at this
temperature for a further 3 hours and then triturated with water and 10 parts
of sodium bicarbonate. The unconsumed benzylaniline is extracted with ether
and the aqueous solution neutralized with dilute hydrochloric acid. By
evaporating this solution and extracting the residue with alcohol there is
obtained 2-(N-phenyl-N-benzylaminomethyl)imidazoline hydrochloride in the form of colorless crystals of melting point 227° to 229°C. | [Therapeutic Function]
Antihistaminic | [Biological Activity]
Imidazoline binding site ligand; a potent inducer of insulin secretion in rat pancreas. Also an antihistamine. | [storage]
Store at -20°C |
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