ChemicalBook--->CAS DataBase List--->26172-54-3

26172-54-3

26172-54-3 Structure

26172-54-3 Structure
IdentificationMore
[Name]

2-Methyl-4-isothiazolin-3-one hydrochloride
[CAS]

26172-54-3
[Synonyms]

2-METHYL-4-ISOTHIAZOLIN-3-ONE HYDROCHLORIDE
MIT HYDROCHLORIDE
2-methyl-3(2h)-isothiazolonhydrochloride
3(2H)-Isothiazolone,2-methyl-,hydrochloride
2-methyl-2H-isothiazol-3-one hydrochloride
2-METHYL-4-ISOTHIAZOLIN-3-ONE HCL
N-MethylisothiazoloneHCl
ISO-THIAZOLINONE(KATHON)
2-METHYLISOTHIAZOLONE (MIT) HCL, 99+%
[EINECS(EC#)]

247-499-3
[Molecular Formula]

C4H6ClNOS
[MDL Number]

MFCD06804636
[Molecular Weight]

151.61
[MOL File]

26172-54-3.mol
Chemical PropertiesBack Directory
[density ]

1.551 at 21℃
[vapor pressure ]

0.777-1Pa at 20-25℃
[storage temp. ]

2-8°C
[solubility ]

DMSO (Slightly), Methanol (Slightly)
[form ]

Solid
[color ]

White to Off-White
[BRN ]

3993054
[LogP]

-0.44 at 20℃ and pH2
[Surface tension]

71.3mN/m at 1g/L and 20℃
[CAS DataBase Reference]

26172-54-3(CAS DataBase Reference)
[EPA Substance Registry System]

26172-54-3(EPA Substance)
Safety DataBack Directory
[Hazard Codes ]

C
[Risk Statements ]

R34:Causes burns.
R42/43:May cause sensitization by inhalation and skin contact .
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
[RIDADR ]

UN 1759 8/PG 2
[WGK Germany ]

3
[HS Code ]

2934100090
Hazard InformationBack Directory
[Application]

Methylisothiazolinone (MIT) has been used:
as a cytotoxic substance to investigate its effect on bronchial epithelial cells (BEAS-2B cells) and its role in apoptotic cell death
to study the effects of tyrosine phosphorylation on focal adhesion kinase (FAK) activity in the development of neural axons and dendrites
[Uses]

Methylisothiazolinone (MIT) has been used:
  • as a cytotoxic substance to investigate its effect on bronchial epithelial cells (BEAS-2B cells) and its role in apoptotic cell death
  • to study the effects of tyrosine phosphorylation on focal adhesion kinase (FAK) activity in the development of neural axons and dendrites
[Uses]

Pesticidal substituted 3-isothiazolinones
[General Description]

2-Methyl-4-isothiazolin-3-one hydrochloride (MIT) is a derivative of the synthetic isothiazolinone.
[Biochem/physiol Actions]

2-Methyl-4-isothiazolin-3-one hydrochloride (MIT) is a skin sensitizer known to cause contact dermatitis and allergy. It is extensively used in the cosmetic industry as a preservative. MIT is a neurotoxin and its prolonged exposure may lead to neuronal death and inhibition of neurite outgrowth.
[storage]

store at 2°C - 8°C,close container well.
Well-known Reagent Company Product InformationBack Directory
[Sigma Aldrich]

26172-54-3(sigmaaldrich)
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