ChemicalBook--->CAS DataBase List--->30924-93-7

30924-93-7

30924-93-7 Structure

30924-93-7 Structure
IdentificationMore
[Name]

Boc-L-Glutamic acid 1-benzyl ester
[CAS]

30924-93-7
[Synonyms]

1-BENZYL N-BOC-L-GLUTAMATE
1-BENZYL N-(TERT-BUTOXYCARBONYL)-L-GLUTAMATE
BOC-GLU-OBZL
BOC-GLUTAMIC ACID-OBZL
BOC-L-GLU-OBZL
BOC-L-GLUTAMIC ACID 1-BENZYL ESTER
BOC-L-GLUTAMIC ACID A-BENZYL ESTER
BOC-L-GLUTAMIC ACID-ALPHA-BENZYL ESTER
N-ALPHA-T-BOC-L-GLUTAMIC ACID ALPHA-BENZYL ESTER
N-ALPHA-T-BUTOXYCARBONYL-L-GLUTAMIC ACID ALPHA-BENZYL ESTER
N-ALPHA-TERT-BUTYLOXYCARBONYL-L-GLUTAMIC ACID ALPHA-BENZYL ESTER
N-BOC-L-GLUTAMIC ACID 1-BENZYL ESTER
N-T-BOC-L-GLUTAMIC ACID ALPHA-BENZYL ESTER
N-(TERT-BUTOXYCARBONYL)-L-GLUTAMIC ACID 1-BENZYL ESTER
Boc-Glu-OBzl (cryst.)
Butoxycarbonylglutamicacidbenzylester
N-tert-Butoxycarbonyl-L-glutamic acid 2-benzyl ester
Boc-L-glutamic acid α-benzyl ester
N-Boc-D-glutamic acid a-benzyl ester
N-T-BOC-L-GLUTAMIC ACID-A-BENZYL ESTERCR YSTALLINE
[Molecular Formula]

C17H23NO6
[MDL Number]

MFCD00065568
[Molecular Weight]

337.37
[MOL File]

30924-93-7.mol
Chemical PropertiesBack Directory
[Melting point ]

95.0 to 99.0 °C
[Boiling point ]

522.6±50.0 °C(Predicted)
[density ]

1?+-.0.06 g/cm3(Predicted)
[refractive index ]

-30 ° (C=0.7, MeOH)
[storage temp. ]

−20°C
[solubility ]

Chloroform (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

4.48±0.10(Predicted)
[color ]

White
[Optical Rotation]

-27.1°(C=0.01g/mI, MEOH, 20°C, 589nm)
[BRN ]

2482076
[InChI]

InChI=1S/C17H23NO6/c1-17(2,3)24-16(22)18-13(9-10-14(19)20)15(21)23-11-12-7-5-4-6-8-12/h4-8,13H,9-11H2,1-3H3,(H,18,22)(H,19,20)/t13-/m0/s1
[InChIKey]

CVZUKWBYQQYBTF-ZDUSSCGKSA-N
[SMILES]

C(OCC1=CC=CC=C1)(=O)[C@H](CCC(O)=O)NC(OC(C)(C)C)=O
[CAS DataBase Reference]

30924-93-7(CAS DataBase Reference)
Safety DataBack Directory
[Safety Statements ]

24/25
[WGK Germany ]

3
[HS Code ]

29242990
Hazard InformationBack Directory
[Description]

Boc-Glu-OBzl is an amino acid building block. It has been used in the synthesis of peptide-based inhibitors of human caspases and human rhinovirus (HRV) 3C protease that have enzyme inhibitory activity in vitro.
[Chemical Properties]

White Solid
[Uses]

Boc-L-Glutamic acid 1-benzyl ester is an effective substrate for vitamin K-dependent carboxylase,it is a monopeptide used to study the interaction of nucleic acid bases with peptides.
[Uses]

N-Boc-L-glutamic Acid α-Benzyl Ester is an effective substrate for vitamin K-dependent carboxylase. N-Boc-L-glutamic Acid α-Benzyl Ester is a monopeptide used to study the interaction of nucleic acid bases with peptides.
[reaction suitability]

reaction type: Boc solid-phase peptide synthesis
[storage]

Store at -20°C
[References]

[1] M GARCIA-CALVO. Inhibition of human caspases by peptide-based and macromolecular inhibitors.[J]. The Journal of Biological Chemistry, 1998, 273 49: 32608-32613. DOI: 10.1074/jbc.273.49.32608
[2] PETER S. DRAGOVICH. Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 2. Peptide Structure?Activity Studies[J]. Journal of Medicinal Chemistry, 1998, 41 15: 2819-2834. DOI: 10.1021/jm9800696
Spectrum DetailBack Directory
[Spectrum Detail]

Boc-L-Glutamic acid 1-benzyl ester(30924-93-7)MS
Boc-L-Glutamic acid 1-benzyl ester(30924-93-7)1HNMR
Boc-L-Glutamic acid 1-benzyl ester(30924-93-7)13CNMR
Boc-L-Glutamic acid 1-benzyl ester(30924-93-7)IR1
Boc-L-Glutamic acid 1-benzyl ester(30924-93-7)IR2
Well-known Reagent Company Product InformationBack Directory
[Sigma Aldrich]

30924-93-7(sigmaaldrich)
[TCI AMERICA]

1-Benzyl N-(tert-Butoxycarbonyl)-L-glutamate,>98.0%(T)(30924-93-7)
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