| Identification | More | [Name]
Boc-L-Glutamic acid 1-benzyl ester | [CAS]
30924-93-7 | [Synonyms]
1-BENZYL N-BOC-L-GLUTAMATE
1-BENZYL N-(TERT-BUTOXYCARBONYL)-L-GLUTAMATE
BOC-GLU-OBZL
BOC-GLUTAMIC ACID-OBZL
BOC-L-GLU-OBZL
BOC-L-GLUTAMIC ACID 1-BENZYL ESTER
BOC-L-GLUTAMIC ACID A-BENZYL ESTER
BOC-L-GLUTAMIC ACID-ALPHA-BENZYL ESTER
N-ALPHA-T-BOC-L-GLUTAMIC ACID ALPHA-BENZYL ESTER
N-ALPHA-T-BUTOXYCARBONYL-L-GLUTAMIC ACID ALPHA-BENZYL ESTER
N-ALPHA-TERT-BUTYLOXYCARBONYL-L-GLUTAMIC ACID ALPHA-BENZYL ESTER
N-BOC-L-GLUTAMIC ACID 1-BENZYL ESTER
N-T-BOC-L-GLUTAMIC ACID ALPHA-BENZYL ESTER
N-(TERT-BUTOXYCARBONYL)-L-GLUTAMIC ACID 1-BENZYL ESTER
Boc-Glu-OBzl (cryst.)
Butoxycarbonylglutamicacidbenzylester
N-tert-Butoxycarbonyl-L-glutamic acid 2-benzyl ester
Boc-L-glutamic acid α-benzyl ester
N-Boc-D-glutamic acid a-benzyl ester
N-T-BOC-L-GLUTAMIC ACID-A-BENZYL ESTERCR YSTALLINE | [Molecular Formula]
C17H23NO6 | [MDL Number]
MFCD00065568 | [Molecular Weight]
337.37 | [MOL File]
30924-93-7.mol |
| Chemical Properties | Back Directory | [Melting point ]
95.0 to 99.0 °C | [Boiling point ]
522.6±50.0 °C(Predicted) | [density ]
1?+-.0.06 g/cm3(Predicted) | [refractive index ]
-30 ° (C=0.7, MeOH) | [storage temp. ]
−20°C
| [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
4.48±0.10(Predicted) | [color ]
White | [Optical Rotation]
-27.1°(C=0.01g/mI, MEOH, 20°C, 589nm) | [BRN ]
2482076 | [InChI]
InChI=1S/C17H23NO6/c1-17(2,3)24-16(22)18-13(9-10-14(19)20)15(21)23-11-12-7-5-4-6-8-12/h4-8,13H,9-11H2,1-3H3,(H,18,22)(H,19,20)/t13-/m0/s1 | [InChIKey]
CVZUKWBYQQYBTF-ZDUSSCGKSA-N | [SMILES]
C(OCC1=CC=CC=C1)(=O)[C@H](CCC(O)=O)NC(OC(C)(C)C)=O | [CAS DataBase Reference]
30924-93-7(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Description]
Boc-Glu-OBzl is an amino acid building block.1,2 It has been used in the synthesis of peptide-based inhibitors of human caspases and human rhinovirus (HRV) 3C protease that have enzyme inhibitory activity in vitro. | [Chemical Properties]
White Solid | [Uses]
Boc-L-Glutamic acid 1-benzyl ester is an effective substrate for vitamin K-dependent carboxylase,it is a monopeptide used to study the interaction of nucleic acid bases with peptides.
| [Uses]
N-Boc-L-glutamic Acid α-Benzyl Ester is an effective substrate for vitamin K-dependent carboxylase. N-Boc-L-glutamic Acid α-Benzyl Ester is a monopeptide used to study the interaction of nucleic acid bases with peptides. | [reaction suitability]
reaction type: Boc solid-phase peptide synthesis | [storage]
Store at -20°C | [References]
[1] M GARCIA-CALVO. Inhibition of human caspases by peptide-based and macromolecular inhibitors.[J]. The Journal of Biological Chemistry, 1998, 273 49: 32608-32613. DOI: 10.1074/jbc.273.49.32608
[2] PETER S. DRAGOVICH. Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 2. Peptide Structure?Activity Studies[J]. Journal of Medicinal Chemistry, 1998, 41 15: 2819-2834. DOI: 10.1021/jm9800696 |
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