| Identification | More | [Name]
N-(tert-Butoxycarbonyl)glycylglycine | [CAS]
31972-52-8 | [Synonyms]
(2-TERT-BUTOXYCARBONYLAMINO-ACETYLAMINO)-ACETIC ACID
BOC-GLY-GLY-OH
BOC-L-GLYCYL GLYCINE
N-(2-N-BOC-AMINO-ACETYL)-GLYCINE
BOC-GLYCYLGLYCINE
N-(tert-Butoxycarbonyl)glycylglycine | [EINECS(EC#)]
1533716-785-6 | [Molecular Formula]
C9H16N2O5 | [MDL Number]
MFCD00038558 | [Molecular Weight]
232.23 | [MOL File]
31972-52-8.mol |
| Chemical Properties | Back Directory | [Melting point ]
132 °C | [Boiling point ]
488.1±30.0 °C(Predicted) | [density ]
1.222±0.06 g/cm3(Predicted) | [storage temp. ]
-15°C | [solubility ]
soluble in Methanol | [form ]
Powder | [pka]
3.41±0.10(Predicted) | [color ]
White | [InChI]
1S/C9H16N2O5/c1-9(2,3)16-8(15)11-4-6(12)10-5-7(13)14/h4-5H2,1-3H3,(H,10,12)(H,11,15)(H,13,14) | [InChIKey]
HWBAHOVOSOAFLE-UHFFFAOYSA-N | [SMILES]
CC(C)(C)OC(=O)NCC(=O)NCC(O)=O | [CAS DataBase Reference]
31972-52-8(CAS DataBase Reference) |
| Safety Data | Back Directory | [Risk Statements ]
43 | [Safety Statements ]
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
WGK 3 | [HS Code ]
2922.19.9690 | [HazardClass ]
IRRITANT | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral
Skin Sens. 1 |
| Hazard Information | Back Directory | [Chemical Properties]
White powder | [Uses]
Boc-Gly-Gly-OH is a Glycine (HY-Y0966) derivative[1]. | [Synthesis]
GENERAL METHODS: Amino acids or peptides (1 mmol) were added dropwise to a solution of ethanol (1 mL) containing guanidine hydrochloride (15 mmol) and di-tert-butyl dicarbonate (2.5-3 mmol) under stirring conditions, and the temperature of the reaction was maintained at 35-40°C. The reaction mixture was stirred continuously until a clarified solution was formed. Subsequently, the ethanol was removed by evaporation under reduced pressure. The residue was washed sequentially with distilled water (2 mL) and hexane or petroleum ether (2 mL) to obtain high purity N-Boc amino acids or N-Boc peptides. If further improvement of product purity is required, the crude product can be purified by recrystallization. | [References]
[1] Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144. DOI:10.1080/10408398.2012.708368 |
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J & K SCIENTIFIC LTD.
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18210857532 18210857532 |
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https://www.jkchemical.com |
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Alfa Aesar
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400-6106006 |
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http://chemicals.thermofisher.cn |
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Energy Chemical
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400-0056266 |
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www.energy-chemical.com |
| Company Name: |
China Langchem Inc.
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0086-21-58956006 |
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www.chemicalbook.com/ShowSupplierProductsList19141/0_EN.htm |
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