ChemicalBook--->CAS DataBase List--->3669-41-8

3669-41-8

3669-41-8 Structure

3669-41-8 Structure
IdentificationMore
[Name]

2',4'-Dihydroxy-2-phenylacetophenone
[CAS]

3669-41-8
[Synonyms]

1-(2,4-DIHYDROXYPHENYL)-2-PHENYLETHAN-1-ONE
1-(2,4-DIHYDROXYPHENYL)-2-PHENYLETHANONE
2',4'-DIHYDROXY-2-PHENYLACETOPHENONE
ALPHA-PHENYLRESACETOPHENONE
AURORA 15288
BENZYL 2,4-DIHYDROXYPHENYL KETONE
OTAVA-BB BB0107930004
TIMTEC-BB SBB008378
2-Phenyl-2',4'-dihydroxyacetophenone
4'-Dihydroxy-2-phenylacetophenone
2'',4''-Dihydroxy-ALPHA-phenylacetophenone
2,4-Dihydroxydeoxybenzoin
2',4'-Dihydroxy-α-phenylacetophenone
α-Phenyl-2',4'-dihydroxyacetophenone
[Molecular Formula]

C14H12O3
[MDL Number]

MFCD00043754
[Molecular Weight]

228.24
[MOL File]

3669-41-8.mol
Chemical PropertiesBack Directory
[Appearance]

off-white crystalline powder
[Melting point ]

112-116 °C(lit.)
[Boiling point ]

225°C/10mmHg(lit.)
[density ]

1.278±0.06 g/cm3(Predicted)
[storage temp. ]

Sealed in dry,Room Temperature
[solubility ]

soluble in Methanol
[form ]

powder to crystal
[pka]

7.74±0.35(Predicted)
[color ]

White to Light yellow to Light orange
[CAS DataBase Reference]

3669-41-8(CAS DataBase Reference)
[NIST Chemistry Reference]

2,4-Dihydroxyphenylbenzyl ketone(3669-41-8)
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P261-P264-P271-P280-P302+P352-P305+P351+P338
[Hazard Codes ]

Xi
[Risk Statements ]

R36/37/38:Irritating to eyes, respiratory system and skin .
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection .
[WGK Germany ]

3
[HS Code ]

29145000
Hazard InformationBack Directory
[Chemical Properties]

off-white crystalline powder
[Uses]

1-(2,4-Dihydroxyphenyl)-2-phenylethanone is used in preparation of substituted pyrazoles, pyrimidines, triazoles and related heterocycles as c-MYC targeting agents for treatment of cancer and other proliferative diseases.
[Preparation]

Preparation by Friedel–Crafts acylation of resorcinol with phenylacetyl chloride in the presence of aluminium chloride,
? in methylene chloride (85%) ;
? in nitrobenzene at 70–80° for 15 min (<80%), at r.t. for 24 h (63%) or for 2 days (60%);
? in ethyl ether at r.t. for 24 h (43%).
Spectrum DetailBack Directory
[Spectrum Detail]

2',4'-Dihydroxy-2-phenylacetophenone(3669-41-8)1HNMR
2',4'-Dihydroxy-2-phenylacetophenone(3669-41-8)IR
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

Benzyl 2,4-dihydroxyphenyl ketone, 98%(3669-41-8)
[Sigma Aldrich]

3669-41-8(sigmaaldrich)
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