| Identification | More | [Name]
2-(Aminomethyl)-1-Boc-piperidine | [CAS]
370069-31-1 | [Synonyms]
(1-AMINOMETHYL-PROPYL)-METHYL-CARBAMIC ACID TERT-BUTYL ESTER
1-BOC-2-AMINOMETHYL-PIPERIDINE
1-N-BOC-2-(AMINOMETHYL)PIPERIDINE
1-PIPERIDINECARBOXYLIC ACID, 2-(AMINOMETHYL)-, 1,1-DIMETHYLETHYL ESTER
2-(AMINOMETHYL)-1-BOC-PIPERIDINE
2-(AMINOMETHYL)-1-N-BOC-PIPERIDINE
2-AMINOMETHYL-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
N-BOC-2-AMINOMETHYLPIPERIDINE
TIMTEC-BB SBB011303
tert-butyl 2-(aminomethyl)piperidine-1-carboxylate | [Molecular Formula]
C11H22N2O2 | [MDL Number]
MFCD01317791 | [Molecular Weight]
214.3 | [MOL File]
370069-31-1.mol |
| Chemical Properties | Back Directory | [Boiling point ]
299.4±13.0 °C(Predicted) | [density ]
1.0124 g/mL at 25 °C | [refractive index ]
n20/D 1.4745 | [Fp ]
110 °C | [storage temp. ]
Keep in dark place,Inert atmosphere,2-8°C | [solubility ]
Soluble in DMSO. | [form ]
liquid | [pka]
10.32±0.29(Predicted) | [Appearance]
Colorless to light yellow Liquid | [Optical Rotation]
-0.1°(C=0.01 g/ml CHCL3) | [InChI]
InChI=1S/C11H22N2O2/c1-11(2,3)15-10(14)13-7-5-4-6-9(13)8-12/h9H,4-8,12H2,1-3H3 | [InChIKey]
PTVRCUVHYMGECC-UHFFFAOYSA-N | [SMILES]
N1(C(OC(C)(C)C)=O)CCCCC1CN | [CAS DataBase Reference]
370069-31-1(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,N | [Risk Statements ]
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin .
R50:Very Toxic to aquatic organisms. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S61:Avoid release to the environment. Refer to special instructions safety data sheet . | [RIDADR ]
UN 3082 9/PG 3 | [WGK Germany ]
3 | [HazardClass ]
9 | [HazardClass ]
IRRITANT | [HS Code ]
29242990 | [Storage Class]
10 - Combustible liquids | [Hazard Classifications]
Acute Tox. 4 Oral
Aquatic Acute 1
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Hazard Information | Back Directory | [Chemical Properties]
White powder | [Uses]
Reactant for synthesis of: TRPV1 antagonists, CHK1 inhibitors, p38a MAP kinase inhibitors, Carbamoylphosphonates, Macrolactams via carbonylation/intramolecular amidation, Intramolecular transamidation. | [Application]
Reactant for synthesis of:
TRPV1 antagonists
CHK1 inhibitors
p38a MAP kinase inhibitors
Carbamoylphosphonates
Macrolactams via carbonylation/intramolecular amidation
Intramolecular transamidation | [Reactions]
2-(Aminomethyl)-1-Boc-piperidine, also known as Tert-butyl 2-(aminomethyl)piperidine-1-carboxylate, is an important organic reagent that can be used as a building block for the synthesis of many organic compounds, such as tert-butyl 2 - ((2, 6 - dimethyl-phenyl amide) methyl) piperidine -1 - carboxylic esters which can be used for preparing medicines in the fields of local anaesthesia or analgesia.
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