ChemicalBook--->CAS DataBase List--->144222-22-0

144222-22-0

144222-22-0 Structure

144222-22-0 Structure
IdentificationMore
[Name]

1-Boc-4-(aminomethyl)piperidine
[CAS]

144222-22-0
[Synonyms]

1-BOC-4-(AMINOMETHYL)PIPERIDINE
1-BOC-4-PIPERIDYLMETHYLAMINE
1-PIPERIDINECARBOXYLIC ACID, 4-(AMINOMETHYL)-, 1,1-DIMETHYLETHYL ESTER
1-T-BUTYLOXYCARBONYL-4-AMINOMETHYL-PIPERIDINE
4-AMINOMETHYL-1-BOC-PIPERIDINE
4-(AMINOMETHYL)-1-N-BOC-PIPERIDINE
4-AMINOMETHYL-1-N-(T-BUTOXYCARBONYL)PIPERIDINE
4-(AMINOMETHYL)-1-(TERT-BUTOXYCARBONYL)PIPERIDINE
4-(AMINOMETHYL)-BOC-PIPERIDINE
4-AMINOMETHYL-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
BOC-4-(AMINOMETHYL)-PIPERIDINE
BOC-PIP(4-AM)
BUTTPARK 90\06-09
N-BOC-(4-AMINOMETHYL)PIPERIDINE
TERT-BUTYL-4-(AMINOMETHYL)PIPERIDINE-1-CARBOXYLATE
TERT-BUTYL 4-(AMINOMETHYL)TETRAHYDROPYRIDINE-1(2H)-CARBOXYLATE
1-N-Boc-4-(aminomethyl)piperidine
4-(Aminomethyl)piperidine, N-BOC protected
1-TERT-BUTOXYCARBONYL-4-AMINOMETHYLPIPERIDINE
N’-BOC-4-aminomethylpirrolidine
[Molecular Formula]

C11H22N2O2
[MDL Number]

MFCD01076207
[Molecular Weight]

214.3
[MOL File]

144222-22-0.mol
Chemical PropertiesBack Directory
[Boiling point ]

237-238 °C(lit.)
[density ]

1.013 g/mL at 25 °C(lit.)
[refractive index ]

n20/D 1.473(lit.)
[Fp ]

>230 °F
[storage temp. ]

Keep in dark place,Sealed in dry,Room Temperature
[solubility ]

Soluble in chloroform and methanol.
[form ]

Liquid or Low Melting Solid
[pka]

10.13±0.29(Predicted)
[color ]

Colorless to yellow
[InChI]

InChI=1S/C11H22N2O2/c1-11(2,3)15-10(14)13-6-4-9(8-12)5-7-13/h9H,4-8,12H2,1-3H3
[InChIKey]

KLKBCNDBOVRQIJ-UHFFFAOYSA-N
[SMILES]

N1(C(OC(C)(C)C)=O)CCC(CN)CC1
[CAS DataBase Reference]

144222-22-0(CAS DataBase Reference)
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)Environment (GHS09)
GHS07,GHS09
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335-H400
[Precautionary statements ]

P261-P273-P305+P351+P338-P280a-P304+P340-P405-P501a
[Hazard Codes ]

Xi,C
[Risk Statements ]

R36/37/38:Irritating to eyes, respiratory system and skin .
R34:Causes burns.
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S24/25:Avoid contact with skin and eyes .
S23:Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer) .
[RIDADR ]

UN 3082 9 / PGIII
[WGK Germany ]

3
[F ]

10-34
[Hazard Note ]

Irritant
[REACH Registrations]

Active
[HazardClass ]

IRRITANT
[HS Code ]

29339900
[Storage Class]

10 - Combustible liquids
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Ethanol-->Sodium hydroxide-->Ethyl acetate-->Methanol-->Tetrahydrofuran-->Dichloromethane-->Petroleum ether-->Sodium carbonate-->Triethylamine-->Lithium Aluminum Hydride-->1,4-Dioxane-->Di-tert-butyl dicarbonate-->Benzaldehyde-->Tosyl chloride-->Sodium amide-->1,1'-Carbonyldiimidazole-->Isonipecotic acid-->4-Methylmorpholine-->Sodium bisulfate-->4-Piperidinemethanol
Hazard InformationBack Directory
[Chemical Properties]

White Low Melting Solid
[Uses]

1-Boc-4-(aminomethyl)piperidine is a protected 4-substituted piperidinecarboxylate used in the preparation of orally active platelet-activating factor antagonists as well as other biologically active compounds.
[Synthesis]

1-Boc-4-aminomethylpiperidine is an organic intermediate that can be prepared from tert-butyl 4-(hydroxymethyl)piperidine-1-carboxylate in three steps.
Spectrum DetailBack Directory
[Spectrum Detail]

1-Boc-4-(aminomethyl)piperidine(144222-22-0)1HNMR
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

tert-butyl 4-(aminomethyl)tetrahydropyridine-1(2H)-carboxylate(144222-22-0)
[Sigma Aldrich]

144222-22-0(sigmaaldrich)
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