| Identification | More | [Name]
5-Methoxy-2-mercaptobenzimidazole | [CAS]
37052-78-1 | [Synonyms]
1,3-DIHYDRO-5-METHOXY-2H-BENZIMIDAZOLE-2-THIONE
2-MERCAPTO-5-METHOXY-1H-BENZIMIDAZOLE
2-MERCAPTO-5-METHOXYBENZIMIDAZOLE
5-METHOXY-1H-BENZO[D]IMIDAZOLE-2-THIOL
5-METHOXY-2-BENZIMIDAZOLETHIOL
5-METHOXY-2-MERCAPTOBENZIMIDAZOLE
5-METHOXY-2-THIOBENZIMIDAZOLE
5-Methoxybenzimidazole-2-thiol
H 118/87
LABOTEST-BB LT01596137
TIMTEC-BB SBB000219
5-Methoxye-2-mercaplobenzinidazole
5-methoxy-2(1H)-benzimidazolinethione
5-methoxy-2-thiohydroxy benzimidazole
2-Mercato-5-methoxy benzimidazole
5-METHOXY-2-THIOHYDROXYBENZIMIDAZOLE(INTERMEDIATE OF OMEPRAZOLE)
2-Mercapto-5-MethoxyBenzimidazole(ForOmeprazole)
5-METHOXY-2-BENZIMIDAZOLEETHIOL
2-Mercapto-5-methoxy-1H-benzim
5-Methoxy-2-thiobenzimidazole 99% | [EINECS(EC#)]
253-326-2 | [Molecular Formula]
C8H8N2OS | [MDL Number]
MFCD00134581 | [Molecular Weight]
180.23 | [MOL File]
37052-78-1.mol |
| Chemical Properties | Back Directory | [Appearance]
off-white to light yellowish-brown powder | [Melting point ]
261-263 °C(lit.)
| [Boiling point ]
309.4±44.0 °C(Predicted) | [density ]
1.2425 (rough estimate) | [vapor pressure ]
0.001Pa at 25℃ | [refractive index ]
1.5690 (estimate) | [storage temp. ]
2-8°C | [solubility ]
DMSO (Slightly), Methanol (Sparingly) | [form ]
Powder | [pka]
10.13±0.30(Predicted) | [color ]
Off-white to light yellow-brown | [Water Solubility ]
insoluble | [Sensitive ]
Air Sensitive | [Detection Methods]
HPLC,NMR | [BRN ]
3605123 | [InChI]
1S/C8H8N2OS/c1-11-5-2-3-6-7(4-5)10-8(12)9-6/h2-4H,1H3,(H2,9,10,12) | [InChIKey]
KOFBRZWVWJCLGM-UHFFFAOYSA-N | [SMILES]
COc1ccc2[nH]c(S)nc2c1 | [LogP]
1.52-2.399 | [CAS DataBase Reference]
37052-78-1(CAS DataBase Reference) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H315-H319-H335 | [Precautionary statements ]
P305+P351+P338 | [Hazard Codes ]
Xi,Xn | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R37:Irritating to the respiratory system.
R22:Harmful if swallowed. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [REACH Registrations]
Active | [HazardClass ]
IRRITANT | [HS Code ]
29339900 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral
Aquatic Chronic 3
Skin Sens. 1 |
| Questions And Answer | Back Directory | [Description]
2-Mercapto-5-methoxybenzimidazole is used in the preparation of COX-2 inhibitors. It is also employed in the preparation of compounds such as 5-methoxy-2[[(4-methoxy-3, 5-dimethyl-2-pyridinyl) methyl] sulfonyl]-1H-benzimidazole, 5-methoxy-2[[(4-methoxy-3, 5-dimethylpyridin-2-yl-1-oxide) methyl] sulfonyl]-1H-benzimidazole as well as tris[μ-1,2-bis(diphenylphosphino)ethane]-1:2κ2P:P′;1:3κ2P:P′;2:3κ2P:P′-di-μ-bromido-1:2κ4Br:Br-bromido-3κBr-tricopper(I) acetone hemisolvate. Furthermore, it acts as a hetercocyclic building block and serves as an intermediate of drug omeprazole1. Finally, it acts as an intermediate for manufacture of the anti-ulcer drug Omeprazole.
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| Hazard Information | Back Directory | [Chemical Properties]
off-white to light yellowish-brown powder | [Uses]
Reagent used in the synthesis of COX-2 inhibitors | [General Description]
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards | [Flammability and Explosibility]
Notclassified |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
|