| Identification | More | [Name]
Ufiprazole | [CAS]
73590-85-9 | [Synonyms]
2-{[(3,5-dimethyl-4-methoxy-2-pyridinyl)-methyl]-thio}-5-methoxy-1h-benzimidazole
2-[(4-METHOXYETHOXY-3,5-DIMETHYL-2-PYRIDINYL)-METHYLTHIO]-5-METHOXYBENZIMIDAZOLE
5-METHOXY-2-[[(3,5-DIMETHYL-4-METHOXY PYRIDINYL)-METHYL]THIO]-1H-BENZIMIDAZOLE
5-METHOXY-2-(4-METHOXY-3,5-DIMETHYL-2-PYRIDINYL)METHYLMERCAPTOBENZIMIDAZOLE
5-METHOXY-2-(4-METHOXY-3,5-DIMETHYL-2-PYRIDINYL)METHYL THIO-1H-BENZIMIDAZOLE
H 168/22
OMEPRAZOLE SULPHIDE
ufiprazole
5-METHOXY-2-(4-METHOXYL-3,5-DIMETHYL-PYRIDINE-2-YLMETHYLSULFENYL)-1H-BENZIMIDA
Omeprazolesulfide
5-METHOXY-2-(4-METHOXY-3,5-DIMETHYL-2-PYRIDINYL)METHYLTHIO-1H-BENZIMIDAZOLE(UFIPRAZOLE)
2-{[(3,5-Dimethyl-4-methoxy-2-pyridinyl)-methyl]-thio}-5-methoxy-1H benzimi
5-METHOXY-2-(4-METHOXY-3,5-DIMETHYL-2-PYRIDINYL)METHYL THIO-1H-BENZIMIDAZOLE =98%
(1R,2S,5R)-menthyl-5(s)-cytosin-1-yl-1,3-oxathiolane-2R-carboxylate(CME)
5-METHOXY-2-{[(3,5-DIMETHYL-4-METHOXY-2-PYRIDINYL)METHYL]THIO}-1H-BENZIMIDAZOLE (OMEPRAZOLE SULFIDE)
(1R,2S,5R)-MENTHYL-5(S)-CYTOSINE-1-YL-[1,3]-OXATHIOLANE-2R-CARBOXYLATE
( IR, 2S, 5R)-menthyl C5(s)-cytosin C1-yl-[1,3] Coxathiolane-2R-carboxylate (CME)
5-METHOXY-2-(4-METHOXY-3,5-DIMETHYL-2-PYRIDINYL)METHYL THIO-1H-BENZIMIDAZOLE(INTERMEDIATE OF OMEPRAZOLE)
2-[(3,5-Dimethyl-4-methoxy-2-pyridyl)methylthio]-5-methoxy-1H-benzimidazole
2-[[(3,5-Dimethyl-4-methoxy-2-pyridyl)methyl]thio]-5-methoxy-1H-benzimidazole | [EINECS(EC#)]
615-997-3 | [Molecular Formula]
C17H19N3O2S | [MDL Number]
MFCD00869021 | [Molecular Weight]
329.42 | [MOL File]
73590-85-9.mol |
| Chemical Properties | Back Directory | [Melting point ]
122.0 to 126.0 °C | [Boiling point ]
539.7±60.0 °C(Predicted) | [density ]
1.28±0.1 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
9.81±0.10(Predicted) | [color ]
White to Off-White | [Usage]
A metabolite of Omeprazole | [λmax]
307nm(MeOH)(lit.) | [Major Application]
pharmaceutical small molecule | [Cosmetics Ingredients Functions]
SKIN CONDITIONING | [InChI]
InChI=1S/C17H19N3O2S/c1-10-8-18-15(11(2)16(10)22-4)9-23-17-19-13-6-5-12(21-3)7-14(13)20-17/h5-8H,9H2,1-4H3,(H,19,20) | [InChIKey]
XURCIPRUUASYLR-UHFFFAOYSA-N | [SMILES]
C1(SCC2=NC=C(C)C(OC)=C2C)NC2=CC(OC)=CC=C2N=1 | [CAS DataBase Reference]
73590-85-9(CAS DataBase Reference) |
| Questions And Answer | Back Directory | [Synthesis]
Ufiprazole can be synthesized by the condensation reaction of 2-mercapto-5-methoxybenzimidazole and 2-chloromethyl-4-methoxy-3,5-lutidine. |
| Hazard Information | Back Directory | [Description]
Omeprazole sulfide is an intermediate used in the production of the gastric proton pump inhibitors, omeprazole and esomeprazole . As a degradation product, it is reported to be a direct-acting inhibitor of cytochrome P450 2C19 in pooled human liver microsomes (IC50 = 9.7 μM). | [Uses]
A metabolite of Omeprazole | [Uses]
Omeprazole Sulfide (Esomeprazol EP Impurity C(Omeprazole EP Impurity C)) is a metabolite of Omeprazole. | [Definition]
ChEBI: Omeprazole sulfide is a member of benzimidazoles. | [Biological Activity]
Ufiprazole (Omeprazole sulfide) is an intermediate in the production of gastric proton pump inhibitors omeprazole and esomeprazole. | [References]
[1] Patent: CN108409714, 2018, A. Location in patent: Paragraph 0049-0054; 0063-0067; 0076-0080; 0089-0093
[2] Patent: CN106632256, 2017, A. Location in patent: Paragraph 0008
[3] Patent: CN107400117, 2017, A. Location in patent: Paragraph 0058-0060
[4] Patent: CN107400118, 2017, A. Location in patent: Paragraph 0046; 0047; 0048
[5] Patent: WO2011/12957, 2011, A1. Location in patent: Page/Page column 16 |
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| Company Name: |
J & K SCIENTIFIC LTD.
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| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Energy Chemical
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400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
Jia Xing Isenchem Co.,Ltd
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0573-85285100 18627885956 |
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https://www.chemicalbook.com/ShowSupplierProductsList14265/0_EN.htm |
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