| Identification | More | [Name]
Methyl 4-amino-2-chlorobenzoate | [CAS]
46004-37-9 | [Synonyms]
2-chioro-4-aminobenzoic acid methyl ester
4-AMINO-2-CHLORO-BENZOIC ACID METHYL ESTER
AKOS BB-3102
METHYL 4-AMINO-2-CHLOROBENZOATE
2-chloro-4-amino benzoic acid methyl ester
Methyl 2-Chloro-4-Aminobenzoate | [Molecular Formula]
C8H8ClNO2 | [MDL Number]
MFCD03840484 | [Molecular Weight]
185.61 | [MOL File]
46004-37-9.mol |
| Chemical Properties | Back Directory | [Melting point ]
112-114°C | [Boiling point ]
334.2±22.0 °C(Predicted) | [density ]
1.311±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [solubility ]
soluble in Chloroform | [form ]
powder to crystal | [pka]
1.41±0.10(Predicted) | [color ]
White to Almost white | [InChI]
InChI=1S/C8H8ClNO2/c1-12-8(11)6-3-2-5(10)4-7(6)9/h2-4H,10H2,1H3 | [InChIKey]
DSHBGNPOIBSIOQ-UHFFFAOYSA-N | [SMILES]
C(OC)(=O)C1=CC=C(N)C=C1Cl | [CAS DataBase Reference]
46004-37-9(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Chemical Properties]
off white powder | [Uses]
Methyl 4-Amino-2-chlorobenzoate is used as a reagent to synthesize selective LXR agonists that increase HDL levels and reverse cholesterol transport in mice. | [References]
[1] Patent: WO2010/65760, 2010, A1. Location in patent: Page/Page column 150
[2] Journal of Medicinal Chemistry, 2010, vol. 53, # 4, p. 1546 - 1562
[3] Bioorganic and Medicinal Chemistry Letters, 2016, vol. 26, # 17, p. 4377 - 4381
[4] Acad. romine Stud. Cerc. Chim., 1956, vol. 4, p. 175,177
[5] Bioorganic and Medicinal Chemistry, 2003, vol. 11, # 13, p. 2991 - 3013 |
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