Back to ChemicalBook Home--->CAS DataBase List--->51037-30-0

51037-30-0

51037-30-0 Structure

51037-30-0 Structure
IdentificationMore
[Name]

Acipimox
[CAS]

51037-30-0
[Synonyms]

5-methylpyrazine-2-carboxylic acid 4-oxide
ACIPIMOX
5-methyl-2-pyrazinecarboxylicaci4-oxide
5-methyl-2-pyrazinecarboxylicacid4-oxide
4-Oxo-5-Methyl-2-Pyrazine-carboxylic Acid
4-Oxide-5-Methylpyrazine-2-CarboxylicAcid
5-METHYLPYRAZINECARBOXYLICACID4-OXIDE
5-METHYLPYRANZINECARBOXYLIC ACID 4-OXIDE
2-Carboxy-5-methylpyrazine 4-oxide, 5-Methylpyrazinecarboxylic acid 4-oxide
K-9321
Olbemox
Olbetam
5-Carboxy-2-methylpyrazine 1-oxide
Acipimox (5-Methylpyrazinecarboxylic acid 4-oxide)
[EINECS(EC#)]

256-928-3
[Molecular Formula]

C6H6N2O3
[MDL Number]

MFCD00865757
[Molecular Weight]

154.12
[MOL File]

51037-30-0.mol
Chemical PropertiesBack Directory
[mp ]

177-180 °C
[storage temp. ]

2-8°C
[CAS DataBase Reference]

51037-30-0(CAS DataBase Reference)
[EPA Substance Registry System]

51037-30-0(EPA Substance)
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

R36:Irritating to the eyes.
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
[RTECS ]

UQ2453000
Raw materials And Preparation ProductsBack Directory
【Raw materials】

Chloroform-->Hydrogen peroxide-->Maleic anhydride-->5-Methyl-2-pyrazinecarboxylic acid-->Ethyl chloroformate-->Hydrochloric acid
Questions And AnswerBack Directory
[Description]

Acipimox is a potent long-acting antilipolytic nicotinic acid (NA) analog. Like nicotinic acid, acipimox lowers lipids effectively, but unlike nicotinic acid, acipimox is longer acting and therefore much less prone to produce free fatty acid rebounding.
Acipimox is recommended as a lipid-lowering agent to treat hyperlipidemia in patients with noninsulin dependent diabetes mellitus.
[References]

[1] Ana T.M.G. Santomauro, Guenther Boden, Maria E.R. Silva, Dalva M. Rocha, Rosa F. Santos, Mileni J.M. Ursich, Paula G. Strassmann and Bernardo L. Wajchenberg, Overnight Lowering of Free Fatty Acids With Acipimox Improves Insulin Resistance and Glucose Tolerance in Obese Diabetic and Nondiabetic Subjects, Diabetes, 1999, vol. 48, 1836-1841
[2] K. C. Shih, C. F. Kwok, C. M. Hwu, L. C. Hsiao, S. H. Li, Y. F. Liu, L. T. Ho, Acipimox attenuates hypertriglyceridemia in dyslipidemic noninsulin dependent diabetes mellitus patients without perturbation of insulin sensitivity and glycemic control, Diabetes Research and Clinical Practice, 1997, vol. 36, 113-119
Well-known Reagent Company Product InformationBack Directory
[Sigma Aldrich]

51037-30-0(sigmaaldrich)
51037-30-0 suppliers list
Company Name: Jinan Shengqi pharmaceutical Co,Ltd
Tel: 86+18663751872
Fax:
Website: www.shengqipharm.com
Company Name: Henan DaKen Chemical CO.,LTD.
Tel: +86-371-55531817
Fax:
Website: www.dakentech.com
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Fax: 0371-55170693
Website: www.tianfuchem.net
Company Name: Xiamen AmoyChem Co., Ltd
Tel: +86 592-605 1114
Fax:
Website: www.amoychem.com
Company Name: Alchem Pharmtech,Inc.
Tel: 8485655694
Fax:
Website: www.chemicalbook.com/ShowSupplierProductsList454175/0.htm
Company Name: CONIER CHEM AND PHARMA LIMITED
Tel: 86-18523575427
Fax:
Website: https://www.chemicalbook.com/ShowSupplierProductsList617604/0.htm
Company Name: career henan chemical co
Tel: 0086-371-86658258
Fax: 0086-371-86658258
Website: http://www.coreychem.com
Company Name: Shaanxi Dideu Medichem Co. Ltd
Tel: +86-15319487004
Fax: +86-29-88380327
Website: https://www.chemicalbook.com/ShowSupplierProductsList715900/0.htm
Company Name: Target Molecule Corp
Tel: 781-999-5354
Fax:
Website: https://www.targetmol.com/
Company Name: Hefei TNJ Chemical Industry Co.,Ltd.
Tel: 0551-65418671
Fax: 0551-65418697
Website: www.tnjchina.com
Company Name: WinWin Chemical CO., Limited
Tel: 0086-577-64498589
Fax: 0086-577-56994596
Website: https://www.win-winchemical.com/
Company Name: Amadis Chemical Company Limited
Tel: 0086-571-89925085
Fax: 0086-571-89925065
Website: www.amadischem.com
Company Name: Shenzhen Sendi Biotechnology Co.Ltd.  
Tel:0755-23311925 18102838259
Fax:0755-23311925
Website:www.chemicalbook.com/ShowSupplierProductsList30406/0_EN.htm
Company Name: Mainchem Co., Ltd.  
Tel:+86-0592-6210733
Fax:+86-0592-6210733
Website:www.mainchem.com
Company Name: Jinan Winsor Pharmaceutical Co., Ltd  Gold
Tel:
Fax:
Website:http://www.winsorpharm.cn/
Company Name: J & K SCIENTIFIC LTD.  
Tel:010-82848833- ;010-82848833-
Fax:86-10-82849933
Website:http://www.jkchemical.com
Company Name: 3B Pharmachem (Wuhan) International Co.,Ltd.  
Tel:821-50328103-801
Fax:86-21-50328109
Website:
Company Name: TCI (Shanghai) Development Co., Ltd.  
Tel:021-67121386 / 800-988-0390
Fax:021-67121385
Website:https://www.tcichemicals.com/zh/cn/index.html
Tags:51037-30-0 Related Product Information
520-27-4 133876-92-3 162011-90-7 72432-03-2 51037-30-0 5521-55-1 1124-11-4 98-96-4 29094-61-9