| Identification | More | [Name]
1-Chloropropane | [CAS]
540-54-5 | [Synonyms]
1-CHLOROPROPANE
AKOS BBS-00004427
N-PROPYL CHLORIDE
PROPYL CHLORIDE
1-chloro-propan
1-Chlorpropan
Chloropropane
n-C3H7Cl
Propane,1-chloro-
Propylchlorid
Chloropropane,99%
1-CHLOROPROPANE, FOR GC
1-CHLOROPROPANE OEKANAL
1-Chloropropane,99%
1-Chloropropane,97% | [EINECS(EC#)]
208-749-7 | [Molecular Formula]
C3H7Cl | [MDL Number]
MFCD00000995 | [Molecular Weight]
78.54 | [MOL File]
540-54-5.mol |
| Chemical Properties | Back Directory | [Appearance]
CLEAR COLOURLESS LIQUID | [Melting point ]
-123 °C | [Boiling point ]
46-47 °C(lit.)
| [density ]
0.892 g/mL at 25 °C(lit.)
| [vapor density ]
2.71 (vs air)
| [vapor pressure ]
5.51 psi ( 20 °C)
| [refractive index ]
n20/D 1.388(lit.)
| [Fp ]
−25 °F
| [storage temp. ]
Refrigerator (+4°C) + Flammables area | [solubility ]
2.7g/l | [form ]
Liquid | [color ]
Clear colorless | [explosive limit]
2.6-11.1%(V) | [Water Solubility ]
2.7 g/L (20 ºC) | [Thermal Conductivity]
0.11 W/(m·K) at 25 ℃ | [Merck ]
7847 | [BRN ]
1730771 | [Henry's Law Constant]
7.6×10-4 mol/(m3Pa) at 25℃, Brockbank (2013) | [Dielectric constant]
8.5299999999999994 | [InChI]
1S/C3H7Cl/c1-2-3-4/h2-3H2,1H3 | [InChIKey]
SNMVRZFUUCLYTO-UHFFFAOYSA-N | [SMILES]
CCCCl | [LogP]
2.04 at 20℃ | [CAS DataBase Reference]
540-54-5(CAS DataBase Reference) | [NIST Chemistry Reference]
Propane, 1-chloro-(540-54-5) | [EPA Substance Registry System]
540-54-5(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
F,Xn | [Risk Statements ]
R11:Highly Flammable.
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S9:Keep container in a well-ventilated place .
S29:Do not empty into drains . | [RIDADR ]
UN 1278 3/PG 2
| [WGK Germany ]
3
| [RTECS ]
TX4400000
| [Autoignition Temperature]
968 °F | [TSCA ]
TSCA listed | [REACH Registrations]
Active | [HazardClass ]
3.1 | [PackingGroup ]
II | [HS Code ]
29031990 | [Storage Class]
3 - Flammable liquids | [Hazard Classifications]
Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Flam. Liq. 2 | [Safety Profile]
A moderately
poisonous irritant to skin, eyes, and mucous
membranes. Narcotic in high
concentrations. Flammable liquid and
dangerous fire hazard when exposed to heat,
flame, or oxiduers. Moderately explosive
when exposed to flame. Keep away from
heat and open flame; can react vigorously
with oxilzing materials. To fight fire, use
CO2, dry chemical. When heated to
decomposition it emits toxic fumes of Cl-. | [Hazardous Substances Data]
540-54-5(Hazardous Substances Data) | [Toxicity]
LD50 orally in Rabbit: > 2000 mg/kg |
| Hazard Information | Back Directory | [General Description]
A clear colorless liquid. Boiling point 46.6°C. Flash point below 0°F. Less dense than water and slightly soluble in water. Vapors are heavier than air. Irritant and narcotic. | [Reactivity Profile]
1-CHLOROPROPANE(540-54-5) presents a dangerous fire risk. May be incompatible with strong oxidizing and reducing agents. Incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides. | [Air & Water Reactions]
Highly flammable. Slightly soluble in water. | [Hazard]
Highly flammable, dangerous fire risk,
explosive limits in air 2.5–11%. Irritant and nar-
cotic.
| [Health Hazard]
Exposure can cause irritation of eyes, nose and throat. May cause nausea, headache, and vomiting. High concentrations may have a narcotic effect. | [Chemical Properties]
CLEAR COLOURLESS LIQUID | [Uses]
Used in organic synthesis, pesticides, pharmaceutical intermediates. | [Synthesis]
Chloro-n-propane is prepared as follows:
1) Zinc chloride and ammonium chloride are mixed homogeneously according to the molar ratio of 1:1, heated and melted, the temperature is controlled at 340 ℃, and the steam of propanol is passed through | [Purification Methods]
Dry the chloride with MgSO4 and fractionally distil. It can be more extensively purified using extraction with H2SO4 as for n-propyl bromide. Alternatively, Chien and Willard [J Am Chem Soc 75 6160 1953] passed a stream of oxygen containing about 5% ozone through the n-propyl chloride for three times as long as was needed to cause the first coloration of starch iodide paper by the exit gas. After washing with aqueous NaHCO3 to hydrolyse ozonides and remove organic acids, the chloride was dried with MgSO4 and fractionally distilled. [Beilstein 1 IV 189.] |
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