| Identification | More | [Name]
2-Methyl-3-trifluoromethylaniline | [CAS]
54396-44-0 | [Synonyms]
2-METHYL-3-(TRIFLUOROMETHYL)ANILINE
2-METHYL-3-TRIFLUOROMETHYL-PHENYLAMINE
3-AMINO-2-METHYLBENZOTRIFLUORIDE
3-PERFLUOROMETHYL-2-METHYLANILINE
3-TRIFLUOROMETHYL-O-TOLUIDINE
MABTF
2-Methyl-3-Amino Benzotrifluoride
2-methyl-3-thifluoromethylaniline
2-methyl-3-trifluoromethylaniline(MTA)
2-Amino-6-trifluoromethyl toluene
2-Methyl-3-(trifluoromethyl)benzenamine
2-Methyl-3-Trifluoromethylaniline/2-Methyl-3-(Trifluoromethyl)Benzenamine
2-Methyl-3-Trifluoromethylanil
2-methyl-3-trifluoromethylaniline (intermediate of flunixin)
3-Amino-2-methylbenzotrifluoride 98%
3-Amino-2-methylbenzotrifluoride98%
2-METHYL-3-TRIFLUOROMETHYLANILINE (3-AMINO-2-METHYLBENZOTRIFLUORIDE)
3-Trifluoromethyl-2-methylaniline
2-Methyl-3-trifluoromethylaniline (3-Amino-2-methylbenzotrifluor | [EINECS(EC#)]
259-145-5 | [Molecular Formula]
C8H8F3N | [MDL Number]
MFCD00153216 | [Molecular Weight]
175.15 | [MOL File]
54396-44-0.mol |
| Chemical Properties | Back Directory | [Melting point ]
38-42 °C(lit.) | [Boiling point ]
62-64°C 4mm | [density ]
1.237±0.06 g/cm3(Predicted) | [Fp ]
>210 °F
| [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [solubility ]
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) | [form ]
Crystalline Powder | [pka]
3.23±0.10(Predicted) | [color ]
White | [BRN ]
2832865 | [InChI]
InChI=1S/C8H8F3N/c1-5-6(8(9,10)11)3-2-4-7(5)12/h2-4H,12H2,1H3 | [InChIKey]
TWLDBACVSHADLI-UHFFFAOYSA-N | [SMILES]
C1(N)=CC=CC(C(F)(F)F)=C1C | [CAS DataBase Reference]
54396-44-0(CAS DataBase Reference) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H315-H319-H335 | [Precautionary statements ]
P305+P351+P338 | [Hazard Codes ]
Xi,T,T+ | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R26/27/28:Very Toxic by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S24/25:Avoid contact with skin and eyes . | [RIDADR ]
2811 | [WGK Germany ]
3
| [Hazard Note ]
Toxic | [HazardClass ]
6.1 | [HazardClass ]
IRRITANT | [HS Code ]
29214990 | [Storage Class]
11 - Combustible Solids |
| Hazard Information | Back Directory | [Chemical Properties]
White crystalline powder | [Uses]
2-Methyl-3-trifluoromethylaniline is a reactant in the synthesis of methylguanidine derivatives as prospective PET radioligands for the open channel of the NMDA receptor, linked to Alzheimer’s, epilepsy and other neurodegenerative disorders. | [General Description]
2-Methyl-3-(trifluoromethyl)aniline belongs to the trifluoromethylbenzene series. | [Synthesis]
A method for synthesizing 2-methyl-3-trifluoromethyl aniline, which takes 2-chloro-3-trifluoromethyl aniline as a raw material, introduces methylthio on the 2-chloro-3-trifluoromethyl aniline, reacts with sulfonyl chloride to convert the methylthio into chloromethyl, and then neutralizes and hydrogenates to obtain pure 2-Methyl-3-trifluoromethylaniline.
| [References]
[1] Patent: US5248781, 1993, A
[2] Heterocycles, 1994, vol. 38, # 10, p. 2243 - 2246 |
|
| Company Name: |
J & K SCIENTIFIC LTD.
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| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
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| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
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| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
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