| Identification | More | [Name]
Alverine citrate | [CAS]
5560-59-8 | [Synonyms]
ALVERINE CITRATE
ALVERINE CITRATE SALT
BIS-GAMMA-PHENYLPROPYLETHYLAMINE DIHYDROGEN CITRATE
n-ethyl-3,3'-diphenyldipropylamine citrate
N-ETHYL-3,3'-DIPHENYLDIPROPYLAMINE CITRATE SALT
N-ETHYL-3,3-DIPHENYLDIPROPYLAMINE CITRATE SALT
Alverine base or citrate
alverine dihydrogen citrate
Profenil citrate | [EINECS(EC#)]
226-929-3 | [Molecular Formula]
C26H35NO7 | [MDL Number]
MFCD00035086 | [Molecular Weight]
473.56 | [MOL File]
5560-59-8.mol |
| Chemical Properties | Back Directory | [Appearance]
White or almost white, crystalline powder. | [Melting point ]
100-102° | [storage temp. ]
2-8°C | [solubility ]
Slightly soluble in water and in methylene chloride, sparingly soluble in ethanol (96 per cent). | [form ]
neat | [color ]
White to Off-White | [InChIKey]
RYHCACJBKCOBTJ-UHFFFAOYSA-N | [CAS DataBase Reference]
5560-59-8(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Chemical Properties]
White or almost white, crystalline powder. | [Originator]
Alverine citrate,Kemikos | [Uses]
An adrenergic-β3 receptor agonist. Antispasmodic. | [Uses]
anticholinergic | [Definition]
ChEBI: The citrate salt of alverine, resulting from the reaction of equimolar amounts of alvarine and citric acid. An antispasmodic that acts directly on intestinal and uterine smooth muscle, it is used in the treatment of irritable bowel syndrome. | [Manufacturing Process]
2 Methods of producing of alverine:
1. 3-Phenylpropylchloride reacted with ethylamine in the presence potassium
hydroxide and N-ethyl-3,3'-diphenyldipropylamine (alverine) was obtained.
2. 3-Phenylpropenal reacted with ethylamine in the presence hydrogen and Pt
as catalyst and BaSO4 and N-ethyl-3,3'-diphenyldipropylamine (alverine) was
obtained.
In practice it is usually used as citrate. | [Therapeutic Function]
Anticholinergic, Spasmolytic | [storage]
Store at -20°C |
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