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6236-10-8

6236-10-8 Structure

6236-10-8 Structure
IdentificationMore
[Name]

(R)-(-)-CITRAMALIC ACID
[CAS]

6236-10-8
[Synonyms]

(-)-2-HYDROXY-2-METHYLBUTANEDIOIC ACID
2-HYDROXY-2-METHYLBUTANEDIOIC ACID
(-)-2-METHYLMALIC ACID
2-METHYLMALIC ACID
(-)-CITRAMALIC ACID
D(-)-2-METHYLMALIC ACID
D-2-METHYLMALIC ACID
D-(-)-CITRAMALIC ACID
(R)-(-)-2-HYDROXY-2-METHYLBUTANEDIOIC ACID
(R)-2-HYDROXY-2-METHYLSUCCINIC ACID
(R)-(-)-CITRAMALIC ACID
(R)-(-)-Citramalic acid, 98+%
Butanedioic acid, 2-hydroxy-2-methyl-, (2R)-
α-hydroxy-α-methyl-succinic acid
(R)-2-Hydroxy-2-methylsuccinic acid, D-(-)-2-Methylmalic acid
(R)-2-Hydroxy-2-methylbutanedioic acid, (R)-2-Hydroxy-2-methylsuccinic acid, 2-Methylmalic acid, D-(-)-2-Methylmalic acid
(-)-2-Methyl-D-malic acid
(2R)-2-Hydroxy-2-methylsuccinic acid
(2R)-2-Methyl-2-hydroxybutanedioic acid
(R)-2-Methylmalic acid
[Molecular Formula]

C5H8O5
[MDL Number]

MFCD00066438
[Molecular Weight]

148.11
[MOL File]

6236-10-8.mol
Chemical PropertiesBack Directory
[Appearance]

white fine crystalline powder
[Melting point ]

108-110 °C(lit.)
[Boiling point ]

188.68°C (rough estimate)
[density ]

1.2336 (rough estimate)
[refractive index ]

1.3920 (estimate)
[storage temp. ]

2-8°C
[solubility ]

PBS (pH 7.2): 10 mg/ml
[form ]

powder or crystals
[pka]

3.65±0.28(Predicted)
[Optical Rotation]

[α]/D -19.0±1.0°, c = 0.5 in 1 M HCl
[Merck ]

2323
[BRN ]

1723818
[InChI]

1S/C5H8O5/c1-5(10,4(8)9)2-3(6)7/h10H,2H2,1H3,(H,6,7)(H,8,9)/t5-/m1/s1
[InChIKey]

XFTRTWQBIOMVPK-RXMQYKEDSA-N
[SMILES]

C[C@@](O)(CC(O)=O)C(O)=O || C[C@@](O)(CC(O)=O)C(O)=O
[CAS DataBase Reference]

6236-10-8(CAS DataBase Reference)
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

R36/37/38:Irritating to eyes, respiratory system and skin .
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
[WGK Germany ]

3
[F ]

3-10
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Chemical Properties]

white fine crystalline powder
[Definition]

ChEBI: D-citramalic acid is the D-enantiomer of citramalic acid. It is a conjugate acid of a D-citramalate(2-).
[Biological Activity]

Citramalate is a biochemical intermediate known to be involved in several aspects of bacterial metabolismincludingamong othersthe anaerobic metabolism of glutamate via the methylaspartate pathway of Clostridium tetanomorphum.
[References]

[1] D M HOWELL  R H W  H Xu. (R)-citramalate synthase in methanogenic archaea.[J]. Journal of Bacteriology, 1999, 181 1: 331-333. DOI: 10.1128/jb.181.1.331-333.1999
[2] W BUCKEL  H A B. Two pathways of glutamate fermentation by anaerobic bacteria.[J]. Journal of Bacteriology, 1974, 117 3: 1248-1260. DOI: 10.1128/jb.117.3.1248-1260.1974
[3] SILKE FRIEDMANN  Georg F  Birgit E Alber. Properties of succinyl-coenzyme A:D-citramalate coenzyme A transferase and its role in the autotrophic 3-hydroxypropionate cycle of Chloroflexus aurantiacus.[J]. Journal of Bacteriology, 2006, 188 18: 6460-6468. DOI: 10.1128/jb.00659-06
Well-known Reagent Company Product InformationBack Directory
[Sigma Aldrich]

6236-10-8(sigmaaldrich)
[TCI AMERICA]

D-(-)-Citramalic Acid,>95.0%(GC)(6236-10-8)
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