ChemicalBook--->CAS DataBase List--->636-61-3

636-61-3

636-61-3 Structure

636-61-3 Structure
IdentificationMore
[Name]

D(+)-Malic acid
[CAS]

636-61-3
[Synonyms]

D-(+)-APPLE ACID
D-APPLE ACID
D-HYDROXYBUTANEDIOIC ACID
D-HYDROXYSUCCINIC ACID
(+)-D-MALIC ACID
D-(+)-MALIC ACID
D-MALIC ACID
MALIC ACID, D-(+)-
(R)-2-HYDROXYBUTANEDICARBOXYLIC ACID
(R)-2-HYDROXY-SUCCINIC ACID
R(+)-2-HYDROXYSUCCINIC ACID
(r)-hydroxybutanedioic acid
(R)-(+)-HYDROXYSUCCINIC ACID
(R)-HYDROXYSUCCINIC ACID
(R)-(+)-MALIC ACID
(R)-MALIC ACID
Butanedioic acid, hydroxy-, (R)-
hydroxy-,(R)-Butanedioicacid
l(+)-malicaci
D-MALIC ACID 100MG NEAT
[EINECS(EC#)]

211-262-2
[Molecular Formula]

C4H6O5
[MDL Number]

MFCD00004245
[Molecular Weight]

134.09
[MOL File]

636-61-3.mol
Chemical PropertiesBack Directory
[Appearance]

white to light yellow crystal powde
[Melting point ]

98-102 °C (lit.)
[alpha ]

2.2 º (c=3, H2O)
[Boiling point ]

167.16°C (rough estimate)
[bulk density]

600kg/m3
[density ]

1.60
[refractive index ]

6.5 ° (C=10, Acetone)
[storage temp. ]

Store below +30°C.
[solubility ]

Soluble in methanol, ethanol, acetone, ether.
[form ]

Crystalline Powder
[pka]

3.61±0.23(Predicted)
[color ]

White
[PH]

2.2 (10g/l, H2O, 20℃)
[Optical Rotation]

[α]20/D +28.0±2°, c = 5.5% in pyridine
[Water Solubility ]

soluble
[Detection Methods]

T,NMR,M.P
[Merck ]

14,5707
[BRN ]

1723540
[InChI]

1S/C4H6O5/c5-2(4(8)9)1-3(6)7/h2,5H,1H2,(H,6,7)(H,8,9)/t2-/m1/s1
[InChIKey]

BJEPYKJPYRNKOW-UWTATZPHSA-N
[SMILES]

O[C@H](CC(O)=O)C(O)=O
[LogP]

-1.370 (est)
[CAS DataBase Reference]

636-61-3(CAS DataBase Reference)
[NIST Chemistry Reference]

(r)-Hydroxybutanedioic acid(636-61-3)
Safety DataBack Directory
[Symbol(GHS) ]

Corrosion (GHS05)Exclamation Mark (GHS07)
GHS05,GHS07
[Signal word ]

Danger
[Hazard statements ]

H315-H318-H335
[Precautionary statements ]

P261-P280-P305+P351+P338
[Hazard Codes ]

Xi
[Risk Statements ]

R37/38:Irritating to respiratory system and skin .
R41:Risk of serious damage to eyes.
R36/37/38:Irritating to eyes, respiratory system and skin .
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection .
[WGK Germany ]

3
[RTECS ]

ON7260000
[REACH Registrations]

Active
[HS Code ]

29181980
[Storage Class]

11 - Combustible Solids
[Hazard Classifications]

Eye Dam. 1
Skin Irrit. 2
STOT SE 3
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Butanoic acid, 4,4,4-trichloro-3-hydroxy-, (R)- (9CI)-->MALEIC ACID-->(S)-2-CHLOROSUCCINIC ACID-->CHLOROSUCCINIC ACID-->L-Aspartic acid-->DL-Malic acid-->Oxaloacetic acid-->Fumaric acid-->L-Asparagine-->L(+)-Tartaric acid-->Maleic acid-->L-Malic acid
[Preparation Products]

(R)-(-)-3-Pyrrolidinol hydrochloride-->(R)-(+)-1-Benzyl-3-pyrrolidinol-->(R)-3-Hydroxypyrrolidine-->(S)-(+)-3-Quinuclidinol-->2-Butenoic acid, 4-hydroxy-2-methyl-, (E)- (9CI)-->DIISOPROPYL (R)-(+)-MALATE
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

D(+)-Malic acid(636-61-3).msds
Hazard InformationBack Directory
[Chemical Properties]

white to light yellow crystal powde
[Uses]

The naturally occuring isomer is the L-form which has been found in apples and many other fruits and plants. Selective α-amino protecting reagent for amino acid derivatives. Versatile synthon for the preparation of chiral compounds including κ-opioid rece
[Definition]

ChEBI: An optically active form of malic acid having (R)-configuration.
[Biological Activity]

D-(+)-Malic acid, an active isomer of Malic acid, is a competitive inhibitor of L(--)malic acid transport.
[Synthesis]

Malic acid is isolated from immature apples; industrially prepared is obtained by catalytic oxidation of benzene, then reacting with water at high temperature and high pressure to generate maleic anhydride.
[in vitro]

Some bacteria belonging to Arthrobacter, Brevibacterium, Corynebacterium, Pseudomonas, Bacillus, and Acinetobacter produced D-(+)-Malic acid (D-Malic acid) from Maleic acid when the cells grown in a medium containing citraconic acid are reacted aerobically with Maleic acid in the pH 7.0 phosphate buffer containing 0.1% sodium chloride.
Spectrum DetailBack Directory
[Spectrum Detail]

D(+)-Malic acid(636-61-3)1HNMR
D(+)-Malic acid(636-61-3)IR1
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

D(+)-Malic acid, 98%(636-61-3)
[Alfa Aesar]

D-(+)-Malic acid, 98+%(636-61-3)
[Sigma Aldrich]

636-61-3(sigmaaldrich)
[TCI AMERICA]

D-(+)-Malic Acid,>98.0%(GC)(T)(636-61-3)
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