ChemicalBook--->CAS DataBase List--->56-04-2

56-04-2

56-04-2 Structure

56-04-2 Structure
IdentificationMore
[Name]

Methylthiouracil
[CAS]

56-04-2
[Synonyms]

2-THIO-6-METHYLURACIL
4(6)-METHYL-2-THIOURACIL
4-HYDROXY-2-MERCAPTO-6-METHYLPYRIMIDINE
4-HYDROXY-6-METHYL-2-THIOPYRIMIDINE
4-METHYL-2-THIOURACIL
4-OXO-2-MERCAPTO-6-METHYLPYRIMIDINE
6-HYDROXY-2-MERCAPTO-4-METHYLPYRIMIDINE
6-METHYL-2-THIOURACIL
6-METHYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDIN-4-ONE
6-methyl-2-thioxo-2,3-dihydro-1h-pyrimidin-4-one
6-METHYL-4-OXY-2-THIOPYRIMIDINE
AKOS BC-0693
AURORA KA-4696
LABOTEST-BB LT00848091
METHIOCIL
METHYLTHIOURACIL
2,3-dihydro-6-methyl-2-thioxo-4(1h)-pyrimidinon
2,3-Dihydro-6-methyl-2-thioxo-4(1H)-pyrimidinone
2-Mercapto-4-hydroxy-6-methylpyrimidine
2-Mercapto-6-methyl-4-pyrimidone
[EINECS(EC#)]

200-252-3
[Molecular Formula]

C5H6N2OS
[MDL Number]

MFCD00006040
[Molecular Weight]

142.18
[MOL File]

56-04-2.mol
Chemical PropertiesBack Directory
[Appearance]

white powder
[Melting point ]

~330 °C (dec.)(lit.)
[density ]

1.291 (estimate)
[refractive index ]

1.6430 (estimate)
[storage temp. ]

Keep in dark place,Sealed in dry,Room Temperature
[solubility ]

DMSO (Heated), Methanol (Slightly, Heated)
[form ]

Liquid
[pka]

pKa 8.2 (Uncertain)
[color ]

Clear colorless to yellow
[Stability:]

Incompatible with strong oxidizing agents, iodine, metals.
[Water Solubility ]

INSOLUBLE
[Detection Methods]

HPLC
[Merck ]

14,6128
[BRN ]

115648
[InChIKey]

HWGBHCRJGXAGEU-UHFFFAOYSA-N
[CAS DataBase Reference]

56-04-2(CAS DataBase Reference)
[IARC]

2B (Vol. Sup 7, 79) 2001
[NIST Chemistry Reference]

6-Methyl-2-thiouracil(56-04-2)
[Storage Precautions]

Light sensitive
[EPA Substance Registry System]

56-04-2(EPA Substance)
Safety DataBack Directory
[Hazard Codes ]

Xn,Xi
[Risk Statements ]

R22:Harmful if swallowed.
R40:Limited evidence of a carcinogenic effect.
[Safety Statements ]

S36/37:Wear suitable protective clothing and gloves .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
[RIDADR ]

UN 3077 9 / PGIII
[WGK Germany ]

3
[RTECS ]

YR0875000
[Hazard Note ]

Irritant/Possible Carcinogen
[TSCA ]

Yes
[HS Code ]

29335995
[Safety Profile]

Confirmed carcinogen with experimental carcinogenic, neoplastigenic, tumorigenic, and teratogenic data. Poison by intraperitoneal route. Moderately toxic by ingestion. Human teratogenic and reproductive effects by an unspecified route: developmental abnormalities of the endocrine system and effects on newborn including neonatal measures or effects. Experimental reproductive effects. Used to treat hyperthyroidism. When heated to decomposition it emits very toxic fumes of NOx and SOx.
[Hazardous Substances Data]

56-04-2(Hazardous Substances Data)
[Toxicity]

MLD in rabbits (mg/kg): 2486 orally (Simon)
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Sodium carbonate-->Sodium oxide
[Preparation Products]

4-Hydroxy-6-methylpyrimidine-->6-Methyluracil-->6-Methyl-2-(methylthio)pyrimidin-4-ol-->Acetonitrile, 2-[[4-[(4-methoxyphenyl)amino]-6-methyl-2-pyrimidinyl]thio]--->4(1H)-Pyrimidinone, 6-methyl-2-[(phenylmethyl)thio]-
Hazard InformationBack Directory
[General Description]

White crystalline powder with an odor of onions and a bitter taste. A saturated aqueous solution is neutral or slightly acidic.
[Reactivity Profile]

METHYLTHIOURACIL(56-04-2) reacts with strong oxidizing agents. Forms complexes with metals and is oxidized by iodine and other sulfhydryl oxidizing agents .
[Air & Water Reactions]

Insoluble in water.
[Fire Hazard]

Flash point data for this chemical are not available. METHYLTHIOURACIL is probably combustible.
[Chemical Properties]

white powder
[Uses]

antithyroid agent
[Definition]

ChEBI: Methylthiouracil is a pyrimidone.
[storage]

Store at -20°C
[Purification Methods]

Crystallise the thiouracil from a large volume of H2O. Purify it further by dissolving in base, adding charcoal, filtering and acidifying with AcOH. Suspend the wet solid (ca 100g) in boiling H2O (1L), stir and add AcOH (20mL), stir and refrigerate. Collect the product, wash it with cold H2O (4 x 200mL), drain it for several hours then place it in an oven at 70o to constant weight. [IR: Short & Thompson J Chem Soc 168 1952, Foster & Snyder Org Synth Coll Vol IV 638 1063, Beilstein 24 III/IV 1289.]
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

Methylthiouracil(56-04-2).msds
Spectrum DetailBack Directory
[Spectrum Detail]

Methylthiouracil(56-04-2)MS
Methylthiouracil(56-04-2)1HNMR
Methylthiouracil(56-04-2)13CNMR
Methylthiouracil(56-04-2)IR1
Methylthiouracil(56-04-2)IR2
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

4-Hydroxy-2-mercapto-6-methylpyrimidine, 98%(56-04-2)
[Alfa Aesar]

6-Methyl-2-thiouracil, 98%(56-04-2)
[Sigma Aldrich]

56-04-2(sigmaaldrich)
[TCI AMERICA]

6-Methyl-2-thiouracil,>98.0%(T)(56-04-2)
56-04-2 suppliers list
Company Name: Wuhan Fortuna Chemical Co., Ltd
Tel: +86-27-59207850 +86-13986145403 , +86-13986145403
Website: www.fortunachem.com/
Company Name: Hebei Mojin Biotechnology Co., Ltd
Tel: +8613288715578 , +8613288715578
Website: www.mojinchemical.com
Company Name: Capot Chemical Co.,Ltd.
Tel: 571-85586718 +8613336195806 , +8613336195806
Website: http://www.capotchem.com
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: +86-0371-55170693 +86-19937530512 , +86-19937530512
Website: https://www.tianfuchem.com/
Company Name: Shanxi Naipu Import and Export Co.,Ltd
Tel: +86-13734021967 +8613734021967 , +8613734021967
Website: https://www.chemicalbook.com/manufacturer/Chisure/
Company Name: career henan chemical co
Tel: +86-0371-86658258
Website: https://www.coreychem.com/
Company Name: Hebei Guanlang Biotechnology Co., Ltd.
Tel: +86-19930503282 , +86-19930503282
Website: https://www.chemicalbook.com/manufacturer/crovell/
Company Name: Xiamen AmoyChem Co., Ltd
Tel: +86-592-6051114 +8618959220845 , +8618959220845
Website: http://www.amoychem.com/
Company Name: Hubei xin bonus chemical co. LTD
Tel: 86-13657291602
Website: www.chemicalbook.com/ShowSupplierProductsList1549548/0.htm
Company Name: Shanghai Longyu Biotechnology Co., Ltd.
Tel: +8615821988213 , +8615821988213
Website: https://www.chemicalbook.com/manufacturer/shanghai-longyu-biotechnology-164/
Company Name: Chongqing Chemdad Co., Ltd
Tel: +86-023-61398051 +8613650506873 , +8613650506873
Website: http://www.chemdad.com/
Company Name: Alchem Pharmtech,Inc.
Tel: 8485655694
Website: www.chemicalbook.com/ShowSupplierProductsList454175/0.htm
Company Name: CONIER CHEM AND PHARMA LIMITED
Tel: +8618523575427 , +8618523575427
Website: http://www.conier.com/
Company Name: Shaanxi Dideu Medichem Co. Ltd
Tel: +86-029-81148696 +8615536356810 , +8615536356810
Website: www.chemicalbook.com/manufacturer/shaanxi-dideu-medichem-221/
Company Name: Tangshan Moneide Trading Co., Ltd.
Tel: +86-315-8309571 +8615633399667 , +8615633399667
Website: http://www.moneidechem.com/
Company Name: SIMAGCHEM CORP
Tel: +86-13806087780 , +86-13806087780
Website: http://www.simagchem.com/
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000 , +1-00000000000
Website: https://www.targetmol.com/
Company Name: Hebei Miaobian Biotechnology Co., Ltd
Tel: +8617733850068 , +8617733850068
Website: www.chemicalbook.com/ShowSupplierProductsList1314675/0.htm
Tags:56-04-2 Related Product Information
96-33-3 143390-89-0 5380-42-7 127-79-7 51-52-5 51953-17-4 68-11-1 79-19-6 29232-93-7 141-90-2 103-85-5 79-20-9 18479-58-8 1914-99-4 99-76-3 7659-86-1 814-71-1 107-96-0