| Identification | More | [Name]
Pamabrom | [CAS]
606-04-2 | [Synonyms]
2-amino-2-methylpropanol 8-bromotheophyllinate
8-BROMOTHEOPHYLLINE COMPOUND WITH 2-AMINO-2-METHYL-1-PROPANOL (1:1)
PAMABROM
PAMABROM,USP | [EINECS(EC#)]
210-103-4 | [Molecular Formula]
C11H18BrN5O3 | [MDL Number]
MFCD00867328 | [Molecular Weight]
348.2 | [MOL File]
606-04-2.mol |
| Chemical Properties | Back Directory | [Melting point ]
>300°C | [storage temp. ]
Refrigerator | [solubility ]
Methanol, Water | [form ]
neat | [color ]
White | [Merck ]
14,7000 | [InChI]
InChI=1S/C7H7BrN4O2.C4H11NO/c1-11-4-3(9-6(8)10-4)5(13)12(2)7(11)14;1-4(2,5)3-6/h1-2H3,(H,9,10);6H,3,5H2,1-2H3 | [InChIKey]
ATOTUUBRFJHZQG-UHFFFAOYSA-N | [SMILES]
C12NC(Br)=NC=1N(C)C(=O)N(C)C2=O.C(N)(C)(C)CO | [CAS DataBase Reference]
606-04-2(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Chemical Properties]
Pamabrom is White Solid
| [Uses]
Pamabrom analgesics for urinary tract pain and urgency
| [Uses]
Pamabrom is a diuretic used to reduce menstrual pains.
| [in vivo]
Pamabrom (200-800 μg/paw; topical administration) produces a dose-dependent analgesic effect in rats, and its analgesic effect can be blocked by Naloxone (HY-17417A) (50 μg/paw), l-nitro-arginine methyl ester (10-100 μg/paw), 1H-(1,2,4)-oxadiazolo[4,2-a]quinoxalin-1-one (10-100 μg/paw) and K+ channel blockers[1].
| [storage]
Store at -20°C |
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