| Identification | More | [Name]
METHYL 2,5-DIHYDROXYCINNAMATE | [CAS]
63177-57-1 | [Synonyms]
2,5-DIHYDROXYCINNAMIC ACID METHYL ESTER
2,5-DIHYDROXYMETHYLCINNAMATE
ERBSTATIN ANALOG
ERBSTATIN ANALOGUE
METHYL 2,5-DIHYDROXYCINNAMATE
3-(2,5-Dihydroxy-phenyl)-acrylicacidmethylester
Erbstatin analog, Methyl 2,5-dihydroxycinnamate | [Molecular Formula]
C10H10O4 | [MDL Number]
MFCD00132932 | [Molecular Weight]
194.18 | [MOL File]
63177-57-1.mol |
| Chemical Properties | Back Directory | [Appearance]
Yellow-Brown Crystalline Powder | [Melting point ]
178-180°C | [density ]
1.318±0.06 g/cm3 (20 ºC 760 Torr) | [storage temp. ]
−20°C
| [solubility ]
0.1 M NaOH: soluble
| [form ]
crystalline
| [color ]
yellow
| [Water Solubility ]
Soluble in methanol or 0.1M NaOH. Insoluble in water | [Usage]
A stable Erbstatin analogue that inhibits tyrosine kinase. Shown to delay the S-phase induction by epidermal growth factor in quiescent normal rat kidney cells, without affecting the total amount of DNA synthesis | [CAS DataBase Reference]
63177-57-1(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
T | [Risk Statements ]
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed .
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S22:Do not breathe dust .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [WGK Germany ]
3
| [HS Code ]
2918.29.7500 | [HazardClass ]
6.1 |
| Hazard Information | Back Directory | [Chemical Properties]
Yellow-Brown Crystalline Powder | [Uses]
A stable Erbstatin analogue that inhibits tyrosine kinase. Shown to delay the S-phase induction by epidermal growth factor in quiescent normal rat kidney cells, without affecting the total amount of DNA synthesis | [Uses]
An inhibitor of the EGF receptor associated tyrosine kinase | [Definition]
ChEBI: 2,5-dihydroxycinnamic acid methyl ester is a cinnamate ester that is the methyl ester of 2,5-dihydroxycinnamic acid. It has a role as a human urinary metabolite, a plant metabolite, a geroprotector and an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor. It is a cinnamate ester, a member of hydroquinones and a methyl ester. | [storage]
Store at RT |
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