| Identification | More | [Name]
1-Chloro-4-iodobenzene | [CAS]
637-87-6 | [Synonyms]
1-CHLORO-4-IODOBENZENE
4-CHLOROIODOBENZENE
P-CHLOROIODOBENZENE
P-IODOCHLOROBENZENE
1-chloro-4-iodo-benzen
4-Iodochlorobenzene
benzene,1-chloro-4-iodo-
p-chlorophenyliodide
p-iodophenylchloride
1-Chloro-4-Iodobenzene,>99%
4-Iodo-1-chlorobenzene
(4-Chlorophenyl) iodide
1-Iodo-4-chlorobenzene
4-Chlorophenyl iodide | [EINECS(EC#)]
211-305-5 | [Molecular Formula]
C6H4ClI | [MDL Number]
MFCD00001053 | [Molecular Weight]
238.45 | [MOL File]
637-87-6.mol |
| Chemical Properties | Back Directory | [Appearance]
white to light yellow crystal powder | [Melting point ]
53-54 °C(lit.)
| [Boiling point ]
226-227 °C(lit.)
| [density ]
1.8860 | [Fp ]
227 °F
| [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [solubility ]
Chloroform (Slightly, Heated), Methanol (Slightly, Heated) | [form ]
Crystalline Powder or Crystals | [color ]
Off-white to light beige | [Sensitive ]
Light Sensitive | [BRN ]
1634414 | [InChI]
InChI=1S/C6H4ClI/c7-5-1-3-6(8)4-2-5/h1-4H | [InChIKey]
GWQSENYKCGJTRI-UHFFFAOYSA-N | [SMILES]
C1(Cl)=CC=C(I)C=C1 | [CAS DataBase Reference]
637-87-6(CAS DataBase Reference) | [NIST Chemistry Reference]
Benzene, 1-chloro-4-iodo-(637-87-6) | [EPA Substance Registry System]
637-87-6(EPA Substance) |
| Questions And Answer | Back Directory | [Preparation]
The methods for synthesizing 1-Chloro-4-iodobenzene reported in the literature are mainly as follows: (1) p-iodoaniline is used as a raw material and then chlorinated and deamined. p-iodoaniline is expensive and the overall yield is low. (2) p-chloroaniline is used as a raw material and azidation and iodomethane are used to obtain the product. In this process, the operation of aryl azidoalkane is dangerous and can easily cause explosion, which is not conducive to industrial production. (3) p-chloroaniline is used as a raw material and diazotization and iodation are used to obtain the product. Due to the large number of by-products, column chromatography separation is required, and the operation is complicated and not easy to industrialize. |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H302+H312+H332 | [Precautionary statements ]
P261-P264-P280-P301+P312-P302+P352+P312-P304+P340+P312 | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S36/37:Wear suitable protective clothing and gloves .
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [TSCA ]
T | [HazardClass ]
IRRITANT | [HS Code ]
29039990 |
| Hazard Information | Back Directory | [Chemical Properties]
white to light yellow crystal powder | [Uses]
suzuki reaction | [Purification Methods]
Distil it in a vacuum then recrystallise it from EtOH. [Sugden J Chem Soc 1173 1924, Beilstein 5 H 221, 5 III 579, 5 IV 695.] |
|
| Company Name: |
J & K SCIENTIFIC LTD.
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| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
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| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
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