| Identification | More | [Name]
Benzydamine | [CAS]
642-72-8 | [Synonyms]
AURORA KA-7514
BENZYDAMINE
1-benzyl-3-(3-(dimethylamino)propoxy)-1h-indazol
1-Benzyl-3-(3-(dimethylamino)propoxy)-1H-indazole
1H-Indazole, 1-benzyl-3-(3-(dimethylamino)propoxy)-
benzidamine
Benzindamine
N-(3-[(1-Benzyl-1H-indazol-3-yl)oxy]propyl)-N,N-dimethylamine
INDAZOLE,1-BENZYL-3-(3-(DIMETHYLAMINO)PROPOXY)-
Benzydamine (base and/or unspecified salts)
[3-(1-Benzyl-1H-indazol-3-yloxy)propyl]dimethylamine
N,N-dimethyl-3-[[1-(phenylmethyl)-1H-indazol-3-yl]oxy]-1-propanamine
(Benzydamine)
N,N-Dimethyl-3-[[1-(phenylmethyl)-1H-indazol-3-yl]oxy]-1-propanamine | [EINECS(EC#)]
211-388-8 | [Molecular Formula]
C7H9N | [MDL Number]
MFCD00864286 | [Molecular Weight]
107.15 | [MOL File]
642-72-8.mol |
| Safety Data | Back Directory | [WGK Germany ]
WGK 3 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral | [Toxicity]
LD50 orl-rat: 9500 mg/kg ARZNAD 22,711,72 |
| Hazard Information | Back Directory | [Description]
Benzydamine is an analytical reference standard categorized as an analgesic.1 Benzydamine has been abused and is associated with hallucinations, muscle weakness, and excitability.2 This product is intended for research and forensic applications. | [Uses]
Analgesic; antipyretic; anti-inflammatory. | [Definition]
ChEBI: Benzydamine is a member of the class of indazoles carrying benzyl and 3-(dimethylamino)propyl groups at positions 1 and 3 respectively. A locally-acting nonsteroidal anti-inflammatory drug that also exhibits local anaesthetic and analgesic properties. It has a role as a central nervous system stimulant, a non-steroidal anti-inflammatory drug, a hallucinogen, a local anaesthetic and an analgesic. It is a member of indazoles, an aromatic ether and a tertiary amino compound. It is a conjugate base of a benzydamine(1+). | [Brand name]
Tantum (Angelini Francesco, Italy). | [Safety Profile]
Poison by intraperitoneal andintravenous routes. Moderately toxic by ingestion andsubcutaneous routes. When heated to decomposition itemits toxic fumes of NOx. | [References]
[1] YUAN-SHIOU HUANG. The effectiveness of benzydamine hydrochloride spraying on the endotracheal tube cuff or oral mucosa for postoperative sore throat.[J]. Anesthesia and analgesia, 2010, 111 4: 887-891. DOI: 10.1213/ane.0b013e3181e6d82a
[2] JACEK SEIN ANAND Roman P K Magdalena Lukasik Glebocka. Recreational abuse with benzydamine hydrochloride (tantum rosa).[J]. Clinical Toxicology, 2007, 45 2: 198-199. DOI: 10.1080/15563650600981210 |
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