| Identification | Back Directory | [Name]
6-Methyl-2-pyridinemethanamine | [CAS]
6627-60-7 | [Synonyms]
CHEMBRDG-BB 4102566
RARECHEM AL BW 2247
2-aminomethyl-6-methylpyridine
6-METHYL-2-PYRIDINEMETHANAMINE
2-Pyridinemethanamine, 6-methyl-
6-METHYL-PYRIDIN-2-YL-METHYLAMINE
(6-METHYLPYRIDIN-2-YL)METHANAMINE
1-(6-methylpyridin-2-yl)methanamine
C-(6-METHYL-PYRIDIN-2-YL)-METHYLAMINE
1-(6-methylpyridin-2-yl)methanamine(SALTDATA: FREE) | [EINECS(EC#)]
1312995-182-4 | [Molecular Formula]
C7H10N2 | [MDL Number]
MFCD05864530 | [MOL File]
6627-60-7.mol | [Molecular Weight]
122.17 |
| Chemical Properties | Back Directory | [Boiling point ]
55-57 °C(Press: 0.1 Torr) | [density ]
1.027±0.06 g/cm3(Predicted) | [storage temp. ]
under inert gas (nitrogen or Argon) at 2–8 °C | [pka]
8.75±0.39(Predicted) | [Appearance]
Colorless to light yellow Liquid |
| Hazard Information | Back Directory | [Uses]
(6-Methylpyridin-2-yl)methanamine is a pyridine derivative studied as one of the complexing agent. | [Synthesis]
General procedure for the synthesis of 6-methyl-2-pyridinemethanamine from 6-methyl-2-pyridinecarbonitrile: 6-methyl-2-pyridinecarbonitrile (10 g, 84.7 mmol) was dissolved in methanol (100 mL), and 10% palladium/carbon catalyst (1 g) was added under stirring conditions. The reaction mixture was stirred at room temperature overnight under the protection of nitrogen atmosphere. Upon completion of the reaction, the solid catalyst was removed by filtration and the organic solvent was removed by distillation under reduced pressure to afford 6-methyl-2-pyridinemethanamine (9 g, 87% yield). | [References]
[1] Patent: CN106279160, 2017, A. Location in patent: Paragraph 0213; 0218; 0219; 0220
[2] Journal of the American Chemical Society, 2015, vol. 137, # 28, p. 8888 - 8891
[3] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 12, p. 3890 - 3894 |
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