ChemicalBook--->CAS DataBase List--->6627-60-7

6627-60-7

6627-60-7 Structure

6627-60-7 Structure
IdentificationBack Directory
[Name]

6-Methyl-2-pyridinemethanamine
[CAS]

6627-60-7
[Synonyms]

CHEMBRDG-BB 4102566
RARECHEM AL BW 2247
2-aminomethyl-6-methylpyridine
6-METHYL-2-PYRIDINEMETHANAMINE
2-Pyridinemethanamine, 6-methyl-
6-METHYL-PYRIDIN-2-YL-METHYLAMINE
(6-METHYLPYRIDIN-2-YL)METHANAMINE
1-(6-methylpyridin-2-yl)methanamine
C-(6-METHYL-PYRIDIN-2-YL)-METHYLAMINE
1-(6-methylpyridin-2-yl)methanamine(SALTDATA: FREE)
[EINECS(EC#)]

1312995-182-4
[Molecular Formula]

C7H10N2
[MDL Number]

MFCD05864530
[MOL File]

6627-60-7.mol
[Molecular Weight]

122.17
Chemical PropertiesBack Directory
[Boiling point ]

55-57 °C(Press: 0.1 Torr)
[density ]

1.027±0.06 g/cm3(Predicted)
[storage temp. ]

under inert gas (nitrogen or Argon) at 2–8 °C
[pka]

8.75±0.39(Predicted)
[Appearance]

Colorless to light yellow Liquid
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)Corrosion (GHS05)
GHS07,GHS05
[Signal word ]

Danger
[Hazard statements ]

H318-H302-H315-H335
[Precautionary statements ]

P280-P305+P351+P338-P310-P264-P280-P302+P352-P321-P332+P313-P362-P264-P270-P301+P312-P330-P501
[HazardClass ]

IRRITANT
[HS Code ]

2933399990
Hazard InformationBack Directory
[Uses]

(6-Methylpyridin-2-yl)methanamine is a pyridine derivative studied as one of the complexing agent.
[Synthesis]

6-Methylpyridine-2-carbonitrile

1620-75-3

6-Methyl-2-pyridinemethanamine

6627-60-7

General procedure for the synthesis of 6-methyl-2-pyridinemethanamine from 6-methyl-2-pyridinecarbonitrile: 6-methyl-2-pyridinecarbonitrile (10 g, 84.7 mmol) was dissolved in methanol (100 mL), and 10% palladium/carbon catalyst (1 g) was added under stirring conditions. The reaction mixture was stirred at room temperature overnight under the protection of nitrogen atmosphere. Upon completion of the reaction, the solid catalyst was removed by filtration and the organic solvent was removed by distillation under reduced pressure to afford 6-methyl-2-pyridinemethanamine (9 g, 87% yield).

[References]

[1] Patent: CN106279160, 2017, A. Location in patent: Paragraph 0213; 0218; 0219; 0220
[2] Journal of the American Chemical Society, 2015, vol. 137, # 28, p. 8888 - 8891
[3] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 12, p. 3890 - 3894
Spectrum DetailBack Directory
[Spectrum Detail]

6-Methyl-2-pyridinemethanamine(6627-60-7)1HNMR
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