| Identification | Back Directory | [Name]
Benzobarbital | [CAS]
744-80-9 | [Synonyms]
benzonal
744-80-9
Benzobarbita
benzoyluminal
BENZOBARBITAL
BENZOBARBITONE
benzoylluminal
benzoylphenobarbital
Benzoyl phenobarbitone
1-benzoyl-5-ethyl-5-phenyl-barbituricaci
1-benzoyl-5-ethyl-5-phenylbarbituricacid
5-Phenyl-5-ethyl-1-benzoylbarbituric acid
1-benzoyl-5-phenyl-5-ethylbarbituric acid
1-BENZOYL-5-ETHYL-5-PHENYL BARBITORIC ACID
1-(benzoyl)-5-ethyl-5-phenyl-1,3-diazinane-2,4,6-trione
BENZOBARBITAL:1-BENZOYL-5-ETHYL-5-PHENYL BARBITORIC ACID
6(1h,3h,5h)-pyrimidinetrione,1-benzoyl-5-ethyl-5-phenyl-4
1-benzoyl-5-ethyl-5-phenyl-2,4,6-trioxohexahydropyrimidine
5-ethyl-5-phenyl-1-phenylcarbonyl-1,3-diazinane-2,4,6-trione
2,4,6(1H,3H,5H)-Pyrimidinetrione, 1-benzoyl-5-ethyl-5-phenyl- | [EINECS(EC#)]
1592732-453-0 | [Molecular Formula]
C19H16N2O4 | [MDL Number]
MFCD00806921 | [MOL File]
744-80-9.mol | [Molecular Weight]
336.34 |
| Chemical Properties | Back Directory | [Melting point ]
134.5°C | [Boiling point ]
472.83°C (rough estimate) | [density ]
1.3097 (rough estimate) | [refractive index ]
1.5700 (estimate) | [form ]
Solid | [pka]
6.41±0.10(Predicted) |
| Hazard Information | Back Directory | [Chemical Properties]
[Appearance] White crystalline powder with bitter taste [Solubility] Almost insoluble in water, slightly soluble in 95% ethanol, soluble in ether, easily soluble in chloroform [Melting point] 134-137℃ [Clarity and color of solution] 5ml1% 1N NaOH solution should be clear and colorless [Acidity] 6.0-6.8 [Related impurities] Phenobarbital ≤0.8% [Diphenyl derivatives] ≤0.4% (TLC method) [Chloride] ≤0.005% [Sulfate] ≤0.025% [Sulfated ash] ≤0.1% [Heavy metals] ≤0.001% [Content] ≥99.0% | [Uses]
is used in preparation method and composition for treating epilepsy including administering a Cholecystokinin-2 receptor antagonist and combination with antiepileptic agents. | [Safety Profile]
Moderately toxic by ingestion.Experimental reproductive effects. Mutation datareported. When heated to decomposition it emits toxicfumes of NOx. | [Synthesis]
Phenobarbital was synthesized using silver salt of phenobarbital and benzoyl chloride in catalyst-free reaction with about 20% yield. Benzoylphenobarbital was synthesized from phenobarbital and benzoyl chloride using 4 dimethylaminopyridine (abbreviated a |
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