| Identification | More | [Name]
Phosphorus oxybromide | [CAS]
7789-59-5 | [Synonyms]
AURORA KA-1088
PHOSPHOROUS OXYBROMIDE
PHOSPHORUS OXIDE BROMIDE
PHOSPHORUS OXIDE TRIBROMIDE
PHOSPHORUS OXYBROMIDE
PHOSPHORUS(V) TRIBROMIDE OXIDE
PHOSPHORYL BROMIDE
Phosphorictribromide
Phosphorus(V)tribromideoxide,98%min(Assay)
phosphorusoxybromide,molten
Phosphorustribromideoxide
Phosphoryl tribromide
phosphoryltribromide
POBr3
tribromophosphorusoxide
PHOSPHORUS(V) OXYBROMIDE, >95%
Phosphorus Oxytribromide
Phosphorus(V)tribromideoxide,98%min
Phosphorusoxybromide,99%
phosphorus(v) oxybromide | [EINECS(EC#)]
232-177-7 | [Molecular Formula]
BrOP | [MDL Number]
MFCD00036298 | [Molecular Weight]
126.88 | [MOL File]
7789-59-5.mol |
| Chemical Properties | Back Directory | [Appearance]
colorless to grey-brown crystals or fused mass | [Melting point ]
56 °C(lit.)
| [Boiling point ]
192 °C(lit.)
| [density ]
2.82 g/mL at 25 °C(lit.)
| [Fp ]
189°C | [storage temp. ]
Store below +30°C. | [solubility ]
reacts with H2O; soluble in benzene, ethyl ether,chloroform | [form ]
Lump | [color ]
White to yellow | [Specific Gravity]
2.822 | [Water Solubility ]
decomposes | [Sensitive ]
Moisture Sensitive | [Merck ]
14,7348 | [InChIKey]
UXCDUFKZSUBXGM-UHFFFAOYSA-N | [CAS DataBase Reference]
7789-59-5(CAS DataBase Reference) | [NIST Chemistry Reference]
Phosphorus tribromide oxide(7789-59-5) | [Storage Precautions]
Store under nitrogen | [EPA Substance Registry System]
7789-59-5(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
C | [Risk Statements ]
R14:Reacts violently with water.
R34:Causes burns.
R37:Irritating to the respiratory system. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S43:In case of fire, use ... (indicate in the space the precise type of fire-fighting equipment. If water increases the risk add-Never use water) .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S7/8:Keep container tightly closed and dry . | [RIDADR ]
UN 1939 8/PG 2
| [WGK Germany ]
3
| [F ]
10-21 | [Hazard Note ]
Corrosive | [TSCA ]
Yes | [HazardClass ]
8 | [PackingGroup ]
II | [HS Code ]
28129090 | [Safety Profile]
Poison by ingestion,
inhalation, and shin contact. A corrosive
irritant to skin, eyes, and mucous
membranes. A corrosive material. Reacts
with steam, water to produce much heat
with toxic fumes. When heated to decomposition it emits very toxic fumes of
Brand POx. See also BROMIDES. | [Hazardous Substances Data]
7789-59-5(Hazardous Substances Data) |
| Raw materials And Preparation Products | Back Directory | [Raw materials]
Hydrogen bromide-->Bifenthrin | [Preparation Products]
Thiazole-5-carboxaldehyde-->METHYL 5-BROMOPYRAZINE-2-CARBOXYLATE-->2-(TRIFLUOROMETHYL)-5,7-DIMETHYLQUINOLINE-4-CARBOXYLIC ACID-->3-Amino-2-bromopyridine-->2-Bromoquinoline-->2-BROMO-PYRIDIN-3-YLAMINE HCL-->2-BROMO-3-IODO-ISONICOTINIC ACID-->5-CHLORO-2-(TRIFLUOROMETHYL)QUINOLINE-4-CARBOXYLIC ACID-->2-(TRIFLUOROMETHYL)QUINOLINE-4-CARBOXYLIC ACID-->2-Bromoquinoxaline-->5-Amino-2-bromopyridine-->2-Bromo-5-nitropyridine-->Thiazole-4-carboxaldehyde-->2-TRIFLUOROMETHYLQUINOLINE-->5-ACETAMIDO-2-BROMOPYRIDINE-->4-BROMOQUINOLIN-2(1H)-ONE-->3,3,3-Trifluoropropionic acid-->5-Bromothiophene-2-carbaldehyde-->6-Fluoro-4-(trifluoromethyl)quinoline-2-carboxylic acid ,97%-->6-BROMO-2,4-DIMETHOXYPYRIMIDINE-->6-CHLORO-2-(TRIFLUOROMETHYL)QUINOLINE-4-CARBOXYLIC ACID-->5-DIMETHYLAMINO-THIOPHENE-2-CARBALDEHYDE-->2-(TRIFLUOROMETHYL)-5-METHYLQUINOLINE-4-CARBOXYLIC ACID-->6-Bromopurine-->2-Bromo-4-nitroimidazole-->2,4-DIBROMOPYRIMIDINE-->1-(3-METHOXYPROPYL)-PIPERAZINE-->2-Bromo-3-nitropyridine-->2,6-BIS(TRIFLUOROMETHYL)-4-HYDROXYQUINOLINE-->4-bromo-2-(trifluoromethyl)quinoline-->2-CHLORO(BROMO)PYRIMIDINE-->2-BROMO-6-ETHOXYPYRIDINE-4-CARBOXYLIC ACID-->Pyridazine, 3-bromo- (9CI)-->4-BROMO-6-FLUORO-2-(TRIFLUOROMETHYL)QUINOLINE-->4-BROMO-PYRAN-2-ONE-->Pyrimidine, 4-bromo- (8CI,9CI)-->2,4-Dibromothiazole-->2-Bromo-5-nitro-4-picoline-->2,4,6-TRIBROMOPYRIMIDINE-->N-(2-BROMO-3-PYRIDINYL)ACETAMIDE |
| Hazard Information | Back Directory | [General Description]
A colorless crystalline solid or liquid if heated above 133° F with a pungent odor. PHOSPHORUS OXYBROMIDE(7789-59-5) is commonly heated and shipped in a molten state. Soluble in water, but, decomposed by water to hydrobromic and phosphoric acid with evolution of heat. Reacts with organic materials to cause fire. Evolves highly toxic and corrosive gases when exposed to fire. Corrosive to metals and tissue. Used to make other chemicals. | [Reactivity Profile]
PHOSPHORUS OXYBROMIDE is incompatible with water, strong oxidizing agents, alcohols, bases, including amines. May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291]. | [Health Hazard]
CORROSIVE and/or TOXIC; inhalation, ingestion or contact (skin, eyes) with vapors, dusts or substance may cause severe injury, burns or death. Fire will produce irritating, corrosive and/or toxic gases. Reaction with water may generate much heat that will increase the concentration of fumes in the air. Contact with molten substance may cause severe burns to skin and eyes. Runoff from fire control or dilution water may cause pollution. | [Fire Hazard]
EXCEPT FOR ACETIC ANHYDRIDE (UN1715), THAT IS FLAMMABLE, some of these materials may burn, but none ignite readily. May ignite combustibles (wood, paper, oil, clothing, etc.). Substance will react with water (some violently), releasing corrosive and/or toxic gases and runoff. Flammable/toxic gases may accumulate in confined areas (basement, tanks, hopper/tank cars, etc.). Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated or if contaminated with water. Substance may be transported in a molten form. | [Uses]
Phosphorus(V) Oxybromide is a reagent used in the preparation of phosphoryl halide for N-protection of amino acids using group assisted purification (GAP). Phosphorus(V) Oxybromide is a brominating agent. |
| Questions And Answer | Back Directory | [Chemical properties]
It appears as colorless or pale orange crystal with irritating odor. It has a relative density of 2.822, melting temperature of 56 °C, the boiling point of 191.7 ℃ and the evaporation heat of 38 Kj/mol. It is soluble in ether, benzene, chloroform, carbon disulfide, concentrated sulfuric acid. It can be slowly hydrolyzed to phosphoric acid and HBr in water. | [Toxicity]
It has similar toxicity to the phosphorus oxychloride. It can react with water, emitting a white smoke-like, irritant and corrosive hydrogen bromide gas which has strong irritation to the eyes, mucous membranes and skin. The patients having inhaled of the vapor or smoke should be sent away from the contaminated area for rest and keeping warm. If eyes are irritated, rinse with water. Upon severe cases, send for medical treatment. Upon skin contact, first rinse with water, and then thoroughly wash with soap. If burned, go for medical treatment. Upon mistakenly administration, immediately gargle and immediately go to the hospital for treatment. | [Application]
During the chemical process, it can be used as an intermediate and used as the raw materials for manufacturing the bromine flame retardant. | [Preparation]
Phosphorus oxychloride method: take phosphorus oxychloride as raw material and aluminum trichloride as the catalyst, upon heating at about 80 ℃, introduce hydrogen bromide gas for reaction, generating tribromo phosphorus. The reaction is:
POC13 + 3HBr → POBr3 + 3HCl ↑
The produced hydrogen chloride gas during the reaction, after being absorbed by water, can produce dilute hydrochloric acid.
Phosphorus tribromide method: to a round bottom flask equipped with a reflow condenser, add the mixture of phosphorus pentabromide and phosphorus pentoxide (250 g of PBr5/about 30 g of P2O5) and heat slowly to 150 ° C. Phosphorus pentoxide is a bit more than the phosphorus pentabromide in stoichiometry. At this time, one the one hand, pay attention to expel the bromine out; on the other hand, make sure that the reaction is completed within 5h.
Then, 10 g of bromine and equivalent amount of phosphorus pentoxide were added to the melt and refluxed at 150 ° C for several hours. This is because it takes time for the intermediate product, phosphorus tribromide, to be oxidized to phosphorus pentabromide and transited to tribromonic phosphorus. The resultant was subjected to vacuum distillation under reduced pressure. After removing the initial distillate and the phosphorus tribromide contained therein, the trapping was carried out. The receiver is cooled with ice brine to generate tribromo phosphorus. Its reaction is:
3PBr5 + P2O5 → 5POBr3 | [Category]
corrosive items | [Flammability and Hazardous characteristics]
It is subject to decomposition upon coming across water, generating toxic hydrogen bromide gas. | [Storage characteristics warehouse]
ventilated, low temperature and dry; it should be stored separately from combustible product. | [Fire extinguishing agent]
Dry powder |
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