| Identification | More | [Name]
2,5-Dichloropyridin-3-amine | [CAS]
78607-32-6 | [Synonyms]
2,5-DICHLORO-3-AMINOPYRIDINE
2,5-DICHLOROPYRIDIN-3-AMINE
2,5-DICHLORO-PYRIDIN-3-YLAMINE
3-AMINO-2,5-DICHLOROPYRIDINE
BUTTPARK 43\57-86
TIMTEC-BB SBB005503
2,5-Dichloro-3-pyridinamine
2,5-Dichloropyridin-3-amine, 95+%
2,5-Dichloropyridin-3-amine ,98% | [Molecular Formula]
C5H4Cl2N2 | [MDL Number]
MFCD00204157 | [Molecular Weight]
163 | [MOL File]
78607-32-6.mol |
| Chemical Properties | Back Directory | [Melting point ]
124 °C | [Boiling point ]
287.0±35.0 °C(Predicted) | [density ]
1.497±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO, Methanol | [form ]
Solid | [pka]
0.03±0.10(Predicted) | [color ]
Off-White to Pale Beige | [Sensitive ]
Air Sensitive | [Detection Methods]
HPLC | [InChI]
1S/C5H4Cl2N2/c6-3-1-4(8)5(7)9-2-3/h1-2H,8H2 | [InChIKey]
OLZPJUVEGSNIJL-UHFFFAOYSA-N | [SMILES]
Nc1cc(Cl)cnc1Cl | [CAS DataBase Reference]
78607-32-6(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S37/39:Wear suitable gloves and eye/face protection .
S36:Wear suitable protective clothing . | [RIDADR ]
UN 2811 6.1/PG 3 | [WGK Germany ]
3 | [HazardClass ]
6.1 | [HazardClass ]
IRRITANT | [PackingGroup ]
Ⅲ | [HS Code ]
29333990 | [Storage Class]
6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | [Hazard Classifications]
Acute Tox. 3 Oral
Eye Dam. 1
Skin Irrit. 2
STOT SE 3 |
| Hazard Information | Back Directory | [Chemical Properties]
Off-White to Pale Beige Solid | [Uses]
2,5-Dichloropyridin-3-amine serves as a precursor for synthesizing 6-chloro-2-(chloromethyl)thiazolo[5,4-b]pyridine and reacts with 2-(benzyloxy)acetyl chloride to form N-(2,5-dichloropyridin-3-yl)-2-chloroacetamide[1][2]. | [References]
[1]Haydon, D. J., Bennett, J. M., Brown, D., Collins, I., Galbraith, G., Lancett, P., Macdonald, R., Stokes, N. R., Chauhan, P. K., Sutariya, J. K., Nayal, N., Srivastava, A., Beanland, J., Hall, R., Henstock, V., Noula, C., Rockley, C., & Czaplewski, L. (2010). Creating an Antibacterial with in Vivo Efficacy: Synthesis and Characterization of Potent Inhibitors of the Bacterial Cell Division Protein FtsZ with Improved Pharmaceutical Properties. Journal of Medicinal Chemistry, 53(10), 3927–3936. https://doi.org/10.1021/jm9016366
[2]Ding, Z.-C., Ma, X., & Zhou, W. (2012). Convenient and Practical Synthesis of 6-Chloro-2-(chloromethyl)-thiazolo[5,4-b]pyridine. Synthetic Communications, 42(19), 2791–2796. https://doi.org/10.1080/00397911.2011.566408 |
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Alfa Aesar
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Energy Chemical
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Jia Xing Isenchem Co.,Ltd
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