Identification | More | [Name]
Loxoprofen sodium | [CAS]
80382-23-6 | [Synonyms]
LOXOPROFEN SODIUM sodium 2-[4-(2-oxocyclopentyl-1-methyl)phenyl]propionate dihydrate alpha-methyl-4-((2-oxocyclopentyl)methyl)benzeneacetatesodiumsaltdihydrate benzeneaceticacid,alpha-methyl-4-((2-oxocyclopentyl)methyl)-,sodiumsalt,di cs-600 loxoprofensodium(patented-nosupply) loxoprofensodiumdihydrate sodium2-(4-(2-oxocyclopentylmethyl)phenyl)propionatedihydrate LOXOPROFEN NA MONOSODIUM2-[4-(2-OXOCYCLOPENTYLMETHYL)PHENYL]PROPANOATEDIHYDRATE(LOXOPROFENSODIUM) Benzeneacetic acid, a-methyl-4-[(2-oxocyclopentyl)methyl]-, sodium salt (9CI) CS 600 (antiinflammatory) Loxonin Sodium 2-[4-[(2-Oxocyclopentyl)methyl]phenyl]propionate 2-[p-(2-Oxocyclopentylmethyl)phenyl]propionic acid sodium salt Unastin α-Methyl-4-[(2-oxocyclopentyl)methyl]benzeneacetic acid sodium salt | [EINECS(EC#)]
1806241-263-5 | [Molecular Formula]
C15H17NaO3 | [MDL Number]
MFCD00941425 | [Molecular Weight]
268.28 | [MOL File]
80382-23-6.mol |
Hazard Information | Back Directory | [Description]
Loxoprofen sodium i s an antiinflammatory/analgesic agent useful in the management of rheumatoid arthritis and related disorders. It is converted in vivo to the corresponding trans-hydroxycyclopentane analog, through which it appears to exert its activity. | [Originator]
Sankyo (Japan) | [Uses]
anti-inflammatory | [Definition]
ChEBI: A hydrate that is the dihydrate form of loxoprofen sodium. The parent acid, loxoprofen, is a prodrug that is rapidly converted to its active trans-alcohol metabolite following oral administration. | [Brand name]
LOXONIN | [Mechanism of action]
As most NSAIDs, loxoprofen is a non-selective cyclooxygenase inhibitor, and works by reducing the synthesis of prostaglandins from arachidonic acid. | [Side effects]
Adverse effects include anorexia, nausea, vomiting, bleeding, anemia, diarrhea, and constipation. |
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