ChemicalBook--->CAS DataBase List--->823202-99-9

823202-99-9

823202-99-9 Structure

823202-99-9 Structure
IdentificationBack Directory
[Name]

(2S)-beta-Alanyl-L-prolyl-2,4-diamino-N-(phenylmethyl)butanamide acetate
[CAS]

823202-99-9
[Synonyms]

SYN-AKE
Snake tripetide
Syn-Ake acetate
Serpent peptide
snake-tripeptide
Snake trippetide
SYN-AKE/Dipeptide di
(2S)-β-alanyl-L-prolyl-2
Syn-Ake, Snake trippetide
Dipeptide Diaminobutyroyl
H-β-Ala-Pro-Dab-NHBzl.2AcOH
Three peptide of snake venom
β-Ala-Pro-Dab-NHBn .2Acetate
SYN-AKE/Snake trippetide powder
Syn-AKE (β-Ala-Pro-Dab-NH-Bzl.HOAc)
4-diamino-N-(phenylmethyl)-butanamide
(2S)-beta-Alanyl-L-prolyl-2,4-diamino
H-β-Ala-Pro-Dab-NH-benzyl H-β-Ala-Pro-DabNHBz
Dipeptide diaminobutyroyl benzylamide acetate
ipeptide Diaminobutyroyl Benzylamide Diacetate
Dipeptide diaminobutyroyl benzylamide diacetat
Dipeptide Diaminobutyroyl Benzylamine Diacetate
Dipeptide Diaminobutyroyl Benzylamide Diacetate
Dipeptide Diaminobutylroyl Benzylamide Diacetate
Dipeptide Diaminobutyroyl Benzylamide Diacetate, SYN-AKE
(2S)-beta-Alanyl-L-prolyl-2,4-diamino-N-(phenylmethyl)butana
DIPEPTIDE DIAMINOBUTYROYL BENZYLAMIDE DIACETATE/Snake trippetide
(2S)-β-Alanyl-L-prolyl-2,4-diamino-N-(phenylmethyl)butanamide acetate
Dipeptide diaminobutyrylbenzylamide diacetate (snake venom tripeptide)
(2S)-beta-Alanyl-L-prolyl-2,4-diamino-N-(phenylmethyl)butanamide acetate
YN-AKE, Snake trippetide, S, Dipeptide Diaminobutyroyl Benzylamide Diacetate
(2S)-β-alanyl-L-prolyl-2,4-diamino-N-(phenylmethyl)-Butanamide, acetate (1:2)
(2S)-beta-Alanyl-L-prolyl-2,4-diamino-N-(phenylmethyl)butanamide acetate USP/EP/BP
acetic acid,(2S)-N-[(2S)-4-amino-1-(benzylamino)-1-oxobutan-2-yl]-1-(3-aminopropanoyl)pyrrolidine-2-carboxamide
H-Β-ALA-PRO-DAB-NH-BENZYLH-Β-ALA-PRO-DABNHBZ;(2S)-Β-ALANYL-L-PROLYL-2;4-DIAMINO-N-(PHENYLMETHYL)-BUTANAMIDE; DIACETATE
[EINECS(EC#)]

232-697-4
[Molecular Formula]

C19H29N5O3.2(C2H4O2)
[MDL Number]

MFCD16621119
[MOL File]

823202-99-9.mol
[Molecular Weight]

495.58
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMSO:3.0(Max Conc. mg/mL);6.0(Max Conc. mM)
Water:10.0(Max Conc. mg/mL);20.2(Max Conc. mM)
[form ]

A solid
[color ]

White to off-white
[Sequence]

{beta-Ala}-Pro-{Dab-NHBzl}
[Cosmetics Ingredients Functions]

SKIN CONDITIONING
[InChIKey]

COUXNAIGHLPOME-VAOSCPPKNA-N
[SMILES]

C(=O)(O)C.C([C@@H]1CCCN1C(=O)CCN)(=O)N[C@@H](CCN)C(=O)NCC1C=CC=CC=1 |&1:5,17,r|
Safety DataBack Directory
[Symbol(GHS) ]

Skull and Crossbones (GHS06)
GHS06
[Signal word ]

Danger
[Hazard statements ]

H311
[Precautionary statements ]

P280-P302+P352-P312-P322-P361-P363-P405-P501
Hazard InformationBack Directory
[Description]

SYN?-AKE is a small synthetic peptide that helps reduce the appearance of wrinkles and laughter lines – fast. As our skin gets older so the number of expression and laughter lines increases, along with crow’s feet and forehead wrinkles. SYN?-AKE enables the face to relax, reducing wrinkles but without losing the ability to help people express themselves. It’s fast acting, long lasting and fully reversible. New studies have now confirmed that when used earlier in time, SYN?-AKE helps delaying the appearance of wrinkles, with age-freezing effects.
[Uses]

SYN-AKE, is capable of smoothing the skin and reducing the wrinkles due to its muscle-relaxing effect.
[Application]

Syn-ake is a patented anti-aging ingredient developed by the Swedish company, Pentapharm Ltd, designed to mimic the action of snake venom. It is designed to work on relaxing the muscles in the face to reduce the appearance of wrinkles and fine lines. As a skincare ingredient, Syn-ake can be added to most formulation types, such as serums, moisturizers, or most water-based products. It is generally used as the main anti-aging ingredients but also can be formulated alongside other key ingredients to create a more diverse anti-aging product. 
[benefits]

Dipeptide diaminobutyroylbenzylamide diacetate is an antagonist of muscular nicotinic acetylcholinereceptor (nmAChR), acting in a manner similar toWaglerin 1, working for anti-wrinkle due to repeatedmovements of facial muscles.Its recommended dosage is 1~4%.
[Mechanism of action]

Dipeptide diaminobutyroyl benzylamide diacetate's effect focuses on an immediate and lasting relaxation of mimicry wrinkles by blocking the neuronal transmission on the Nicotinic Acetyhlcholin receptor. The peptide is an antagonist of the muscular nicotinic acetylcholine membrane's receptor. As the muscular nicotinic ACh receptors are blocked, the ion channel remains closed. There is no uptake of Na+ and the muscle cells stay relaxed. The transmission of nerve impulses to the muscles is inhibited and facial muscles are relaxed.    
[Biotechnological Applications]

Dipeptide diaminobutyroyl benzylamide diacetate belongs to the "Botox in a jar" type of peptides (similar to Argireline or Leuphasyl) targeting wrinkles caused by facial movements, like laughter lines or crow’s feet.
Spectrum DetailBack Directory
[Spectrum Detail]

Dipeptide diaminobutyroyl benzylamide diacetate(823202-99-9)1HNMR
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