| Identification | More | [Name]
N-Benzylacetoacetamide | [CAS]
882-36-0 | [Synonyms]
ACETOACETBENZYLAMIDE
BENZYLACETOACETAMIDE
BENZYL ACETOACETIC AMIDE
N-ACETOACETYLBENZYLAMINE
N-BENZYLACETOACETAMIDE
3-oxo-n-(phenylmethyl)-butanamid
AAPCT
N-Benzyl-3-Oxo-Butanamide
ACETOACET-BENZYLAMINE
ACETOACETAMINO-BENZYLAMINE
3-Oxo-N-(phenylmethyl)butyramide
N-Benzyl-3-oxobutyramide | [EINECS(EC#)]
212-928-5 | [Molecular Formula]
C11H13NO2 | [MDL Number]
MFCD00026260 | [Molecular Weight]
191.23 | [MOL File]
882-36-0.mol |
| Questions And Answer | Back Directory | [Application]
N-Benzylacetoacetamide can be used to prepare the compound 1-acetyl-N-benzylcyclopentaneformamide: Acetylacetylbenzylamine (100.00 g, 522.93 mmol) and K2CO3 (216.50 g, 1568.79 mmol) were suspended in DMF (1 L), and 1,4-dibromobutane (169.36 g, 784.4 mmol) was added dropwise to the solution at room temperature to obtain the reaction system. The reaction system was then stirred overnight at room temperature. After the reaction was completed, the reaction mixture was concentrated under reduced pressure, the residue was diluted with water (500 mL), and extracted with ethyl acetate (500 mL x 3). The organic phases were then combined. Next, the combined organic phases were washed with saturated brine (500 mL x 3) and dried over anhydrous sodium sulfate. The mixture was then filtered, the filtrate was concentrated under reduced pressure, and the residue was purified by silica gel column chromatography (petroleum ether/ethyl acetate (v/v) = 8/1) to give the title compound as a white solid (69.50 g, 54%). |
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