30544-47-9
中文名称
依托芬那酯
英文名称
Etofenamate
CAS
30544-47-9
分子式
C18H18F3NO4
分子量
369.33
MOL 文件
30544-47-9.mol
更新日期
2026/01/12 11:07:14
30544-47-9 结构式
基本信息
中文别名
依托芬那酯2[[3-(三氟甲基)苯基]氨基]-2-(羟乙氧基)乙基苯甲酸酯
2-(2-羟基乙氧基)乙基 2-[3-(三氟甲基)苯胺基]苯甲酸酯
英文别名
TV-485ReuMon
TVX-485
Rheumon
Bayrogel
Etofenamate
TrauMon Gel
Ethofenamate
EtofenaMate,TV-485
EtofenamateEtofenamate
所属类别
原料药：非甾抗炎药物理化学性质
熔点25°C
沸点bp.001 130-135°
密度1.2866 (estimate)
折射率nD25 1.564
储存条件Refrigerator
溶解度Practically insoluble in water, miscible with ethanol (96 per cent) and with ethyl acetate.
酸度系数(pKa)14.32±0.10(Predicted)
形态neat
颜色Light yellow to yellow
稳定性感光
主要应用pharmaceutical (small molecule)
InChIInChI=1S/C18H18F3NO4/c19-18(20,21)13-4-3-5-14(12-13)22-16-7-2-1-6-15(16)17(24)26-11-10-25-9-8-23/h1-7,12,22-23H,8-11H2
InChIKeyXILVEPYQJIOVNB-UHFFFAOYSA-N
SMILESC(OCCOCCO)(=O)C1=CC=CC=C1NC1=CC=CC(C(F)(F)F)=C1
安全数据
警示词危险
危险性描述H301-H410
危险品运输编号UN2810 - class 6.1 - PG 3 - EHS - Toxic, liquids, organic, n.o.s., HI: all
WGK GermanyWGK 3
存储类别6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
toxic compounds or compounds which causing chronic effects
危险性类别Acute Tox. 3 Oral
Aquatic Acute 1
Aquatic Chronic 1
Aquatic Acute 1
Aquatic Chronic 1
毒性LD50 in male, female rats (mg/kg): 292, 470 orally; 140, 226 i.v.; 373, 397 i.p.; 643, 568 s.c. (Jacobi)